In this article we summarize our personal non-small cell lung cancer (NSCLC) highlights of the virtual ASCO 2020 meeting, covering developments in early and advanced-stage NSCLC. Until recently early stage NSCLC patients were treated independently …

Monoclonal gammopathy of renal significance (MGRS) encompasses a group of kidney disorders in which a monoclonal immunoglobulin secreted by a B cell or plasma cell clone causes renal damage, without meeting hematological criteria for malignancy.

Multiple myeloma (MM) is a cytogenetically heterogeneous and incurable plasma cell disease characterized by clonal proliferation of malignant plasma cells [ 1 ]. It accounts for approximately 10% of all hematological malignancies [ 2 ]. MM is …

The aim of this short review is to summarize “clinical practice changing” abstracts about genitourinary cancers from this year’s ASCO Annual Meeting. The phase 3 JAVELIN Bladder 100 trial showed astonishing overall survival (OS) data up to 22 …

Pharmacological anticancer therapy in elderly people has to account for pharmacokinetic aspects in view of age-related changes in organ function and disease-related alterations. Age-related changes in organ function might still be physiological …

Acute lymphoblastic leukemia (ALL) is a malignant disease of the bone marrow in which early lymphoid precursors proliferate and replace the normal hematopoietic cells, resulting in a marked decrease in normal blood cell production [ 1 ]. ALL …

Physical activity and exercise can have numerous positive effects on various disease- and therapy-related symptoms across the continuum of cancer disease. These include an improvement in quality of life, physical function, aerobic fitness, muscle …

Comorbidity is common among cancer patients and increases with age. Comorbid conditions potentially affect treatment, therapy outcomes, and survival of people with cancer. This short review aims at presenting the prevalence of comorbidities, to …

Chronic lymphocytic leukemia (CLL) is a B-cell malignancy characterized by clonal expansion and accumulation of mature B‑lymphocytes in peripheral blood, bone marrow, and secondary lymphoid tissues [ 1 ]. CLL is highly heterogeneous where some …

Treatment of patients with light-chain amyloidosis (AL amyloidosis) has changed over the last 20 years, and early mortality rates have decreased with prolongation of survival. However, many patients are not cured with conventional therapy.

Delirium is commonly seen in palliative care. It usually develops over a short period of time and is characterized by a disturbance of attention and awareness. As delirium is associated with increased mortality, prevention and early identification …

Geriatric assessments, nutritional counseling and monitoring of muscle health before and during therapy are of high clinical significance in the management of elderly cancer patients. Criteria, data and cut-offs characterizing cancer-related …

Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant hematological condition arising from B‑cells, characterized by the presence of monoclonal immunoglobulin production, also known as paraprotein. It is found in up to 3% of …

Raising awareness of the necessity to adapt cancer therapy to the individual needs and resources of elderly cancer patients is the mission for geriatric oncology in the 21st century. Since its beginnings around the turn of the millennium [ 1 ] …

This article is a brief overview of drugs, which are of use in the treatment of constipation and diarrhoea in palliative care. Whereas most of the drugs mentioned are widely used and known, the aspect of gastrointestinal symptoms as side effect of …