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01.07.2013 | original article | Ausgabe 13-14/2013

Wiener Medizinische Wochenschrift 13-14/2013

Influence of a moderate physical activity intervention on red cell deformability in patients suffering from chronic obstructive pulmonary disease (COPD)

Zeitschrift:
Wiener Medizinische Wochenschrift > Ausgabe 13-14/2013
Autoren:
Dip Sport Sci Basit Ahmad, PhD Sport Sci Nina Ferrari, Dr. med. Georgina Montiel, Prof. Dr. Wilhelm Bloch, Dr. med. Anke Raabe-Oetker, Nina Skrobala, Prof. Dr. Klara Brixius

Summary

The present study investigates whether a moderate physical activity intervention may alter red cell deformability (RCD) of patients suffering from chronic obstructive pulmonary disease (COPD). Subjects (n = 10; age: 62 ± 4; body-mass index (BMI): 25.8 ± 7.5) performed a training regimen for 10 weeks. In the beginning of the study and after the training period, COPD patients underwent a WHO cycle ergometry test. Venous blood samples were taken before (T0), immediately after (T1) and 30 min after (T2) the intervention. RCD was measured with the laser-assisted optical rotational cell analyzer (LORCA). Significant improvements of the RCD were detected. The semi-maximal shear stress increased significantly. Acute exhaustion had no effect on RCD. Thus, the training period of 10 weeks influenced RCD.

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