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Erschienen in: Wiener Medizinische Wochenschrift 9-10/2018

10.11.2016 | review

Histopathologic pitfalls of Mohs micrographic surgery and a review of tumor histology

verfasst von: M.D, Ph.D Katlein França, M.D Yasser Alqubaisy, M.D, Ph.D Ashraf Hassanein, M.D Keyvan Nouri, M.D Torello Lotti

Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 9-10/2018

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Summary

Mohs micrographic surgery is a specialized subset of staged surgical excisions with each subsequent stage being driven largely by the histologic findings of the previous stage. Therefore, it is imperative that histologic analysis is performed in an accurate manner. Frozen section and tissue flattening is a crucial step in Mohs surgery. Frozen sections introduce certain artifacts and these artifacts must be interpreted in the correct context. Basal and squamous cell carcinomas are the most common tumors encountered in Mohs micrographic surgery, and their histopathology is also associated with certain “pitfalls”. Basal cell carcinoma should be distinguished from hair follicles, folliculocentric basaloid proliferations, poromas, nevus sebaceous, desmoplastic trichoepitheliomas, and spiradenomas, to name but a few histologic entities. Similarly, squamous cell carcinoma should be distinguished from hypertrophic actinic keratoses, pseudoepitheliomatous hyperplasia, sebaceous carcinoma, and microcystic adnexal carcinoma. In addition, there are numerous subtypes of basal cell and squamous carcinomas that the Mohs surgeon should be aware of due to differences in the biologic behavior of these tumors. This review presents a number of the common histologic pitfalls of Mohs micrographic surgery and a review of tumor histology.
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Metadaten
Titel
Histopathologic pitfalls of Mohs micrographic surgery and a review of tumor histology
verfasst von
M.D, Ph.D Katlein França
M.D Yasser Alqubaisy
M.D, Ph.D Ashraf Hassanein
M.D Keyvan Nouri
M.D Torello Lotti
Publikationsdatum
10.11.2016
Verlag
Springer Vienna
Erschienen in
Wiener Medizinische Wochenschrift / Ausgabe 9-10/2018
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X
DOI
https://doi.org/10.1007/s10354-016-0528-0