01.01.2015 | main topic
Blockade of co-stimulation in chronic inflammatory diseases
Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 1-2/2015Einloggen, um Zugang zu erhalten
Costimulatory molecules are key elements in T cell activation. Therapeutic inhibition of costimulatory pathways have been recognized as valid therapeutic strategies in the treatment of various inflammatory diseases. This article will describe their mechanisms of action and will summarize the results from clinical trials in the field of rheumatologic diseases.