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Erschienen in: Wiener Medizinische Wochenschrift 1-2/2015

01.01.2015 | main topic

Anti-TNFs in axial spondyloarthritis

verfasst von: MD Roland Kocijan, MD Christian Muschitz, MD Jürgen Rech

Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 1-2/2015

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Summary

Since there is no evidence regarding the efficacy of conventional synthetic disease modifying anti-rheumatic drugs in the improvement of axial spondyloarthritis (SpA), anti-tumor necrosis factors (anti-TNFs) are recommended if nonsteroidal anti-inflammatory drugs fail, or in case of high disease activity. Anti-TNFs show encouraging data regarding pain reduction, improved mobility and quality of life in both ankylosing spondylitis and non-radiographic axial spondyloarthritis. However, withdrawal of anti-TNF therapy leads to relapse of disease activity in SpA. Moreover, osteoproliferation does not seem to be influenced by anti-TNFs.

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Metadaten
Titel
Anti-TNFs in axial spondyloarthritis
verfasst von
MD Roland Kocijan
MD Christian Muschitz
MD Jürgen Rech
Publikationsdatum
01.01.2015
Verlag
Springer Vienna
Erschienen in
Wiener Medizinische Wochenschrift / Ausgabe 1-2/2015
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X
DOI
https://doi.org/10.1007/s10354-014-0338-1