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Erschienen in: Wiener Medizinische Wochenschrift 1-2/2015

01.01.2015 | main topic

Biological agents in psoriatic arthritis

verfasst von: MD Roland Kocijan, MD Christian Muschitz, MD Jürgen Rech

Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 1-2/2015

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Summary

Anti-tumor necrosis factors (TNFs) are effective drugs for the treatment of psoriatic arthritis (PsA) regarding reduction of pain and inflammation, enthesitis, dactylitis, as well as psoriatic skin and nail disease. Moreover, radiographic progression in PsA is decelerated. The efficacy of anti-TNFs seems to be independent of synthetic disease-modifying anti-rheumatic drugs, suggesting only a minor role of combination therapy in PsA. Anti-TNFs are generally well tolerated in patients with PsA. Adverse events are similar to those reported in patients with rheumatoid arthritis. Ustekinumab, a recently approved IL-12/IL-23-antibody is another promising biological agent in the treatment of PsA.

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Metadaten
Titel
Biological agents in psoriatic arthritis
verfasst von
MD Roland Kocijan
MD Christian Muschitz
MD Jürgen Rech
Publikationsdatum
01.01.2015
Verlag
Springer Vienna
Erschienen in
Wiener Medizinische Wochenschrift / Ausgabe 1-2/2015
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X
DOI
https://doi.org/10.1007/s10354-014-0300-2