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Erschienen in: Wiener klinische Wochenschrift 21-22/2013

01.11.2013 | original article

Spectrum of pathogens of in-patient children and youths with community acquired pneumonia: a 3 year survey of a community hospital in Vienna, Austria

verfasst von: MD Herbert Kurz, MD Hubert Göpfrich, PhD Klaus Huber, MD Walter Krugluger, MD Friederike Asbott, PhD Leila Wabnegger, MD Petra Apfalter, MD Christian Sebesta

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 21-22/2013

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Summary

Background

No actual data are available on the epidemiology and morbidity of community acquired pneumonia (CAP) in youths and children in Vienna, Austria.

Objective

The objective was to determine the epidemiology of CAP and morbidity of children hospitalized due to CAP in a tertiary care facility.

Methods

During three winter seasons youths and children hospitalized due to CAP were enrolled. Testing for viral and bacterial pathogens of pneumonia was performed in a routine clinical setting. Blood cultures were performed; respiratory viruses, Mycoplasma pneumoniae and Chlamydia pneumoniae were searched for by an established Real Time polymerase chain reaction (PCR) panel. Clinical signs and indices of inflammation were documented.

Results

Out of 279 children and youths with CAP a causative agent could be detected in 190 (68 %). Viruses and bacteria were diagnosed in 107 (57 %) and 58 patients (30 %), respectively. Co-infection was found in 20 patients (10 %), Mycoplasma pneumoniae or Clamydia pneumoniae in 16 cases (8 %).
In seven patients blood cultures were positive. C-reactive protein (CRP) was significantly higher in children with positive Streptococcus pneumoniae antigen (SPAG) than with viral infection and/or co-infection. Clinical parameters showed no statistically significant differences. C. pneumoniae and M. pneumoniae were only diagnosed in children and youths with 5 years and older.

Conclusions

Testing for pathogens in CAP in clinical routine achieves a high recovery rate. Blood cultures are rarely helpful, but the molecular testing for viruses seemed to be helpful to establish the diagnosis.

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Metadaten
Titel
Spectrum of pathogens of in-patient children and youths with community acquired pneumonia: a 3 year survey of a community hospital in Vienna, Austria
verfasst von
MD Herbert Kurz
MD Hubert Göpfrich
PhD Klaus Huber
MD Walter Krugluger
MD Friederike Asbott
PhD Leila Wabnegger
MD Petra Apfalter
MD Christian Sebesta
Publikationsdatum
01.11.2013
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 21-22/2013
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-013-0426-z