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Wiener klinische Wochenschrift

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28.04.2023 | original article

Physical activity levels respiratory and peripheral muscle strength and pulmonary function in young post-COVID-19 patients

A cross-sectional study

verfasst von: Musa Güneş, PT, MsC, Metehan Yana, PT, PhD, Meral Boşnak Güçlü, PT, PhD

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 9-10/2023

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Summary

Objective

Coronavirus disease 2019 (COVID-19) causes permanent problems, even mild severity. The long-term consequences of COVID-19 are still unknown. This study aimed to investigate physical activity levels, respiratory and peripheral muscle strength, and pulmonary function in the long term in young adult COVID-19 patients who recovered from mild disease.

Methods

This cross-sectional study was carried out at least 6 months after the COVID-19 diagnosis, 54 patients with COVID-19 (median age: 20 years) and 46 controls (median age: 21 years) were compared. Functional status (post-COVID-19 functional status scale), respiratory (maximum inspiratory and expiratory pressures (MIP, MEP)) and peripheral muscle strength (dynamometer), pulmonary function (Spirometry), dyspnea and fatigue (modified Borg scale), and physical activity levels (International Physical Activity Questionnaire) were evaluated. ClinicalTrial number: NCT05381714.

Results

Patients with COVID-19 measured and percent predicted MIP and MEP were statistically decreased compared with the controls (p < 0.05). Shoulder abductors muscle strength (p < 0.001) and the number of individuals with low physical activity levels were significantly higher in patients compared with controls (p = 0.048). Pulmonary function, quadriceps muscle strength, exertional dyspnea, and fatigue scores were similar in groups (p > 0.05).

Conclusion

Respiratory and peripheral muscle strength and physical activity levels are adversely affected in patients with COVID-19, even though the patients were mildly affected in the long term. Also, symptoms such as dyspnea and fatigue may persist. Therefore, these parameters should be evaluated in the long term, even in young adults who are mildly affected by COVID-19.

Vorheriger Artikel Impact of the COVID-19 pandemic on the epidemiology of severe burns

Nächster Artikel Relationship between exercise capacity and impulse oscillometry parameters after COVID-19 infections

Huang Y, Tan C, Wu J, et al. Impact of coronavirus disease 2019 on pulmonary function in early convalescence phase. Respir Res. 2020;21(1):163. https://doi.org/10.1186/s12931-020-01429-6.CrossRefPubMedPubMedCentral

Crook H, Raza S, Nowell J, Young M, Edison P. Long covid-mechanisms, risk factors, and management. BMJ. 2021;374:n1648. https://doi.org/10.1136/bmj.n1648.CrossRefPubMed

Shah W, Hillman T, Playford ED, Hishmeh L. Managing the long term effects of covid-19: summary of NICE, SIGN, and RCGP rapid guideline. BMJ. 2021;372:n136. https://doi.org/10.1136/bmj.n136.CrossRefPubMed

Trinkmann F, Müller M, Reif A, et al. Residual symptoms and lower lung function in patients recovering from SARS-CoV‑2 infection. Eur Respir J. 2021;57(2):2003002. https://doi.org/10.1183/13993003.03002-2020.CrossRefPubMedPubMedCentral

Joshee S, Vatti N, Chang C. Long-term effects of COVID-19. Mayo Clin Proc. 2022;97(3):579–99. https://doi.org/10.1016/j.mayocp.2021.12.017.CrossRefPubMed

Li M, Zhou C, Jiang J, et al. Investigations on the respiratory function in COVID-19 patients: a prospective cohort study. Biomed Res Int. 2021;2021:9928276. https://doi.org/10.1155/2021/9928276.CrossRefPubMedPubMedCentral

Wu Z, McGoogan JM. Characteristics of and important lessons from the Coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese center for disease control and prevention. JAMA. 2020;323(13):1239–42. https://doi.org/10.1001/jama.2020.2648.CrossRefPubMed

Kashif A, Chaudhry M, Fayyaz T, et al. Follow-up of COVID-19 recovered patients with mild disease. Sci Rep. 2021;11(1):13414. https://doi.org/10.1038/s41598-021-92717-8.CrossRefPubMedPubMedCentral

Blanco JR, Cobos-Ceballos MJ, Navarro F, et al. Pulmonary long-term consequences of COVID-19 infections after hospital discharge. Clin Microbiol Infect. 2021;27(6):892–6. https://doi.org/10.1016/j.cmi.2021.02.019.CrossRefPubMedPubMedCentral

10.

Boutou AK, Georgopoulou A, Pitsiou G, et al. Changes in the respiratory function of COVID-19 survivors during follow-up: a novel respiratory disorder on the rise? Int J Clin Pract. 2021;75(10):e14301. https://doi.org/10.1111/ijcp.14301.CrossRefPubMed

11.

Guler SA, Ebner L, Aubry-Beigelman C, et al. Pulmonary function and radiological features 4 months after COVID-19: first results from the national prospective observational Swiss COVID-19 lung study. Eur Respir J. 2021;57(4):2003690. https://doi.org/10.1183/13993003.03690-2020.CrossRefPubMedPubMedCentral

12.

Huang C, Huang L, Wang Y, et al. 6‑month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet. 2021;397(10270):220–32. https://doi.org/10.1016/S0140-6736(20)32656-8.CrossRefPubMedPubMedCentral

13.

Mo X, Jian W, Su Z, et al. Abnormal pulmonary function in COVID-19 patients at time of hospital discharge. Eur Respir J. 2020;55(6):2001217. https://doi.org/10.1183/13993003.01217-2020.CrossRefPubMedPubMedCentral

14.

Lund LC, Hallas J, Nielsen H, et al. Post-acute effects of SARS-CoV‑2 infection in individuals not requiring hospital admission: a Danish population-based cohort study. Lancet Infect Dis. 2021;21(10):1373–82. https://doi.org/10.1016/S1473-3099(21)00211-5.CrossRefPubMedPubMedCentral

15.

Petersen MS, Kristiansen MF, Hanusson KD, et al. Long COVID in the Faroe Islands: a longitudinal study among nonhospitalized patients. Clin Infect Dis. 2021;73(11):4058–63. https://doi.org/10.1093/cid/ciaa1792.CrossRef

16.

Stavem K, Ghanima W, Olsen MK, Gilboe HM, Einvik G. Persistent symptoms 1.5–6 months after COVID-19 in non-hospitalised subjects: a population-based cohort study. Thorax. 2021;76(4):405–7. https://doi.org/10.1136/thoraxjnl-2020-216377.CrossRefPubMed

17.

van Kessel SAM, Olde Hartman TC, Lucassen PLBJ, van Jaarsveld CHM. Post-acute and long-COVID-19 symptoms in patients with mild diseases: a systematic review. Fam Pract. 2022;39(1):159–67. https://doi.org/10.1093/fampra/cmab076.CrossRefPubMed

18.

Lund Berven L, Selvakumar J, Havdal L, et al. Inflammatory markers, pulmonary function, and clinical symptoms in acute COVID-19 among non-hospitalized adolescents and young adults. Front Immunol. 2022;13:837288. https://doi.org/10.3389/fimmu.2022.837288.CrossRefPubMedPubMedCentral

19.

Sandler CX, Wyller VBB, Moss-Morris R, et al. Long COVID and post-infective fatigue syndrome: a review. Open Forum Infect Dis. 2021;8(10):ofab440. https://doi.org/10.1093/ofid/ofab440.CrossRefPubMedPubMedCentral

20.

Klok FA, Boon GJAM, Barco S, et al. The post-COVID-19 functional status scale: a tool to measure functional status over time after COVID-19. Eur Respir J. 2020;56(1):2001494. https://doi.org/10.1183/13993003.01494-2020.CrossRefPubMedPubMedCentral

21.

Plaza M, Sevilla GGP. Respiratory muscle sequelae in young university students infected by coronavirus disease 2019: an observational study. Rev Assoc Med Bras. 2022;68(2):245–9. https://doi.org/10.1590/1806-9282.20211040.CrossRefPubMed

22.

Tanriverdi A, Savci S, Kahraman BO, Ozpelit E. Extrapulmonary features of post-COVID-19 patients: muscle function, physical activity, mood, and sleep quality. Ir J Med Sci. 2022;191(3):969–75. https://doi.org/10.1007/s11845-021-02667-3.CrossRefPubMed

23.

Zu ZY, Jiang MD, Xu PP, et al. Coronavirus disease 2019 (COVID-19): a perspective from China. Radiology. 2020;296(2):15–25. https://doi.org/10.1148/radiol.2020200490.CrossRef

24.

WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004;363(9403):157–63. https://doi.org/10.1016/S0140-6736(03)15268-3.CrossRef

25.

Çalik Kütükcü E, Çakmak A, Kinaci E, et al. Reliability and validity of the Turkish version of post-COVID-19 functional status scale. Turk J Med Sci. 2021;51(5):2304–10. https://doi.org/10.3906/sag-2105-125.CrossRefPubMedPubMedCentral

26.

Wilson RC, Jones PW. A comparison of the visual analogue scale and modified Borg scale for the measurement of dyspnoea during exercise. Clin Sci (Lond). 1989;76(3):277–82. https://doi.org/10.1042/cs0760277.CrossRefPubMed

27.

American Thoracic Society. Lung function testing: selection of reference values and interpretative strategies. Am Rev Respir Dis. 1991;144:1202–18. https://doi.org/10.1164/ajrccm/144.5.1202.CrossRef

28.

Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J. 2005;26(2):319–38. https://doi.org/10.1183/09031936.05.00034805.CrossRefPubMed

29.

Johnson JD, Theurer WM. A stepwise approach to the interpretation of pulmonary function tests. Am Fam Physician. 2014;89(5):359–66.PubMed

30.

American Thoracic Society, European Respiratory Society. ATS/ERS statement on respiratory muscle testing. Am J Respir Crit Care Med. 2002;166(4):518–624. https://doi.org/10.1164/rccm.166.4.518.CrossRef

31.

Evans JA, Whitelaw WA. The assessment of maximal respiratory mouth pressures in adults. Respir Care. 2009;54(10):1348–59.PubMed

32.

Bohannon RW. Reference values for extremity muscle strength obtained by hand-held dynamometry from adults aged 20 to 79 years. Arch Phys Med Rehabil. 1997;78(1):26–32. https://doi.org/10.1016/s0003-9993(97)90005-8.CrossRefPubMed

33.

Saglam M, Arikan H, Savci S, et al. International physical activity questionnaire: reliability and validity of the Turkish version. Percept Mot Skills. 2010;111(1):278–84. https://doi.org/10.2466/06.08.PMS.111.4.278-284.CrossRefPubMed

34.

Craig CL, Marshall AL, Sjöström M, et al. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003;35(8):1381–95. https://doi.org/10.1249/01.MSS.0000078924.61453.FB.CrossRefPubMed

35.

Çelik Z, Güzel NA, Kafa N, Köktürk N. Respiratory muscle strength in volleyball players suffered from COVID-19. Ir J Med Sci. 2021;191(5):1959–65. https://doi.org/10.1007/s11845-021-02849-z.CrossRefPubMedPubMedCentral

36.

Anastasio F, Barbuto S, Scarnecchia E, et al. Medium-term impact of COVID-19 on pulmonary function, functional capacity and quality of life. Eur Respir J. 2021;58(3):2004015. https://doi.org/10.1183/13993003.04015-2020.CrossRefPubMedPubMedCentral

37.

Börü ÜT, Bilgiç AB, Köseoğlu Toksoy C, et al. Prevalence of multiple sclerosis in a Turkish city bordering an iron and steel factory. J Clin Neurol. 2018;14(2):234–41. https://doi.org/10.3988/jcn.2018.14.2.234.CrossRefPubMedPubMedCentral

38.

Int Panis L, Provost EB, Cox B, et al. Short-term air pollution exposure decreases lung function: a repeated measures study in healthy adults. Environ Health. 2017;16(1):60. https://doi.org/10.1186/s12940-017-0271-z.CrossRefPubMedPubMedCentral

39.

Torres-Castro R, Vasconcello-Castillo L, Alsina-Restoy X, et al. Respiratory function in patients post-infection by COVID-19: a systematic review and meta-analysis. Pulmonology. 2021;27(4):328–37. https://doi.org/10.1016/j.pulmoe.2020.10.013.CrossRefPubMed

40.

Van Herck M, Goërtz YMJ, Houben-Wilke S, et al. Severe fatigue in long COVID: web-based quantitative follow-up study in members of online long COVID support groups. J Med Internet Res. 2021;23(9):e30274. https://doi.org/10.2196/30274.CrossRefPubMedPubMedCentral

41.

López-Valenciano A, Suárez-Iglesias D, Sanchez-Lastra MA, Ayán C. Impact of COVID-19 pandemic on university students’ physical activity levels: an early systematic review. Front Psychol. 2021;11:624567. https://doi.org/10.3389/fpsyg.2020.624567.CrossRefPubMedPubMedCentral

42.

Ferrandi PJ, Alway SE, Mohamed JS. The interaction between SARS-CoV‑2 and ACE2 may have consequences for skeletal muscle viral susceptibility and myopathies. J Appl Physiol. 2020;129(4):864–7. https://doi.org/10.1152/japplphysiol.00321.2020.CrossRefPubMedPubMedCentral

43.

Paneroni M, Simonelli C, Saleri M, et al. Muscle strength and physical performance in patients without previous disabilities recovering from COVID-19 pneumonia. Am J Phys Med Rehabil. 2021;100(2):105–9. https://doi.org/10.1097/PHM.0000000000001641.CrossRefPubMed

44.

Jimeno-Almazán A, Pallarés JG, Buendía-Romero Á, et al. Post-COVID-19 syndrome and the potential benefits of exercise. Int J Environ Res Public Health. 2021;18(10):5329. https://doi.org/10.3390/ijerph18105329.CrossRefPubMedPubMedCentral

45.

Jimeno-Almazán A, Buendía-Romero Á, Martínez-Cava A, et al. Effects of a concurrent training, respiratory muscle exercise, and self-management recommendations on recovery from post-COVID-19 conditions: the RECOVE trial. J Appl Physiol. 2023;134(1):95–104. https://doi.org/10.1152/japplphysiol.00489.2022.CrossRefPubMed

46.

Jimeno-Almazán A, Franco-López F, Buendía-Romero Á, et al. Rehabilitation for post-COVID-19 condition through a supervised exercise intervention: a randomized controlled trial. Scand J Med Sci Sports. 2022;32(12):1791–801. https://doi.org/10.1111/sms.14240.CrossRefPubMed

47.

Hasenoehrl T, Palma S, Huber DF, Kastl S, Steiner M, Jordakieva G, Crevenna R. Post-COVID: effects of physical exercise on functional status and work ability in health care personnel. Disabil Rehabil. 2022; https://doi.org/10.1080/09638288.2022.2111467.CrossRefPubMed

Titel: Physical activity levels respiratory and peripheral muscle strength and pulmonary function in young post-COVID-19 patients
A cross-sectional study
verfasst von: Musa Güneş, PT, MsC
Metehan Yana, PT, PhD
Meral Boşnak Güçlü, PT, PhD
Publikationsdatum: 28.04.2023
Verlag: Springer Vienna
Erschienen in: Wiener klinische Wochenschrift / Ausgabe 9-10/2023
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI: https://doi.org/10.1007/s00508-023-02204-5

Springer Medizin Österreich

Summary

Objective

Methods

Results

Conclusion

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