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13.01.2023 | case report

Ovarian yolk sac tumor in a premenarchal girl

verfasst von: MD Antonio Ivan Miletić, MD, PhD med. sc., PhD hum. sc. Prof. Dubravko Habek, MD Filip Medić, MD Matija Prka, MD, PhD Sanja Berić Lerotić, MD, PhD Prof. Fabijan Knežević

Erschienen in: Wiener Medizinische Wochenschrift

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Summary

Yolk sac tumors are highly malignant and commonly affect the ovaries, with a median age of occurrence of 23 years. We describe the case of an ovarian yolk sac tumor in a 12-year-old premenarchal girl suffering from Hashimoto’s thyroiditis and chronic spontaneous urticaria, which presented as a rapidly growing solid cystic formation in the hypogastrium with an extreme increase in alpha fetoprotein (52,778 mg/ml). After ultrasound and MRI imaging, fertility-sparing staging surgery was performed, and the diagnosis of an ovarian yolk sac tumor with positive malignant cells in ascites was confirmed. The specificity of this case is the tumor classification into stage IC3 according to the FIGO and stage III according to the Children’s Oncology Group criteria. The postoperative course was complicated by a pelvic abscess and a subcutaneous suture rejection reaction. Our case may incite further research on the relationship between autoimmunity and yolk sac tumors.
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Metadaten
Titel
Ovarian yolk sac tumor in a premenarchal girl
verfasst von
MD Antonio Ivan Miletić
MD, PhD med. sc., PhD hum. sc. Prof. Dubravko Habek
MD Filip Medić
MD Matija Prka
MD, PhD Sanja Berić Lerotić
MD, PhD Prof. Fabijan Knežević
Publikationsdatum
13.01.2023
Verlag
Springer Vienna
Erschienen in
Wiener Medizinische Wochenschrift
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X
DOI
https://doi.org/10.1007/s10354-022-00996-1