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European Surgery OnlineFirst articles

18.03.2019 | review

Diagnosis and treatment of microvascular invasion in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) ranks among the most common malignancies worldwide [ 1 ]. Hepatectomy and liver transplantation (LT) are the most important HCC treatments [ 2 ]. The 5-year recurrence rate were as high as 70% and 35%, respectively [ …

MD, PhD Rui-Sheng Ke, MD, PhD Qiu-cheng Cai, MD Yong-tai Chen, MD Li-Zhi Lv, MD, PhD Yi Jiang

13.03.2019 | main topic Open Access

Minimally invasive pancreatic surgery—where are we going?

Minimally invasive pancreatic surgery (MIPS) was introduced in the mid-1990s by Gagner and co-workers, who reported laparoscopic pancreatoduodenectomy, enucleation, and distal pancreatectomy [ 1 , 2 ]. Despite these early reports, further …

MD, PhD Mushegh A. Sahakyan, MD, PhD Knut Jørgen Labori, MD Florian Primavesi, MD, PhD Kjetil Søreide, MD, FRCS FEBS PD Stefan Stättner, MD, PhD Bjørn Edwin

12.03.2019 | main topic Open Access

Integrating radiation oncology into the management of pancreatic cancer

Although some improvements have been made in recent years, the prognosis of pancreatic ductal adenocarcinoma remains poor. Surgical resection followed by adjuvant systemic therapy is the only curative treatment option in early stage disease. The …

Robert Jäger, Rocco Weigel, Britta Forthuber, Ute Ganswindt

05.03.2019 | main topic Open Access

Molecular biology in pancreatic ductal adenocarcinoma: implications for future diagnostics and therapy

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal of all cancers with mortality almost equal to the incidence of the disease [ 1 ]. PDAC is refractory to almost all current therapies. Despite being a devastating disease, only …

MD, PhD Kjetil Søreide, MD Florian Primavesi, MD, PhD Knut J. Labori, MSc Martin M. Watson, MD PD Dr. Stefan Stättner

01.03.2019 | original article

Systematic review and meta-analysis on the treatment of diffuse esophageal spasm

Diffuse esophageal spasm (DES) is a rare condition with an annual incidence of 0.2/100,000, occurring in some 3–5% of esophageal motility disorder (OMD) cases [ 1 , 2 ]. It is more likely to occur in patients over the age of 50 years and should be …

Harry Vercoe, MD Mubashir Mulla, FRCS Wyn G. Lewis, FRCS Antonio Foliaki, FRCS David S. Y. Chan

25.02.2019 | original article

Effect of fast-track surgery on inflammatory response and immune function in patients with laparoscopic distal gastrectomy

Fast-track surgery (FTS) is also known as enhanced recovery after surgery (ERAS); FTS has been applied to gastric cancer surgery for nearly 10 years and mainly adopts various active and effective measures during the perioperative period to reduce …

Qiang Hu, Tianzhu He, Yuanshui Sun, Fengyong Wang, Jinfeng Wu

13.02.2019 | case report

Laparoscopic Heller myotomy after Roux-en-Y gastric bypass

Achalasia is a rare primary esophageal motility disorder characterized by loss of physiological esophageal body peristalsis and lack of relaxation of the lower esophageal sphincter (LES). Dysphagia, regurgitation, chest pain, cough, and weight …

MD Alberto Aiolfi, MD Stefania Tornese, MD Lavinia Barbieri, MD Valerio Panizzo, MD Giancarlo Micheletto, MD Davide Bona

30.01.2019 | original article

Outcomes after thoracic endovascular aortic repair in patients with traumatic thoracic aortic injuries—a single-centre retrospective review

Blunt traumatic thoracic aortic injury (BTAI) caused by motor vehicle accidents and less commonly by other blunt thoracic trauma constitutes a surgical emergency. These injuries are often attended with high mortality rates. Two main treatment …

Nkhabe Chinyepi, Mpapho Joseph Motsumi, Nadraj Naidoo

29.01.2019 | review Open Access

A review of online platforms in training and surgical education

In surgical education, the use of technology has evolved during the past three decades. Audio cassettes constituted a modest technical starting point that quickly evolved into video tapes and films of operative procedures [ 1 – 3 ]. A technological …

MBChB, MHPE, MFSTEd, FHEA, MD Dr. Michael El Boghdady, PhD Assoc. Prof. Béatrice Marianne Ewalds-Kvist, MBChB, PhD, FRCS Dr. Afshin Alijani

24.01.2019 | original article

Changes in liver function tests after laparoscopic cholecystectomy with low- and high-pressure pneumoperitoneum

Pneumoperitoneum is one of the key elements in laparoscopic surgery that provides visual clarity and space for safe and effective surgery. However, it can cause intraoperative adverse respiratory, cardiovascular, hepatic, and renal effects [ 1 ].

Zagor Zagorac, MD, PhD Rastko Zivic, Miljan Milanovic, Berislav Vekic, Branislav Dakovic, Zoran Bukumiric, Dragan Radovanovic

15.01.2019 | short communication

Rumination syndrome after esophagectomy

Two female patients, aged 51 and 59 years, were referred to our tertiary-care esophageal center for refractory food regurgitation after esophagectomy and gastric conduit replacement performed in 2007 and 2012, respectively. Indications for …

MD Daniele Bernardi, MD Emanuele Asti, MD Lavinia Barbieri, MD, FACS Luigi Bonavina

10.12.2018 | original article

Does giving pasireotide to patients undergoing pancreaticoduodenectomy always pay for itself?

The rate of postoperative complications following pancreaticoduodenectomy can be as high as 50% [ 1 ]. Postoperative pancreatic fistula is the most common postoperative complication and also the leading cause of postoperative mortality following …

MD Fang Yuan, PhD Amiram Gafni, PhD Chu-Shu Gu, MD MSc Pablo E. Serrano

25.07.2018 | case report

Biliary intraepithelial neoplasia in liver parenchyma of the caudate lobe: honeycomb appearance

The concept of biliary intraepithelial neoplasia BilIN was established in 2005, and a consensus was reached on the terminology in 2007 [ 1 , 2 ]. In the 2010 revision of the WHO classification of tumors, BilIN and IPNB (intra-papillary neoplasm of …

M.D. Tokio Higaki, M.D. Shintaro Yamazaki, M.D. Masahiko Sugitani, M.D. Tadatoshi Takayama