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Erschienen in: Wiener klinische Wochenschrift 13-14/2021

27.05.2021 | short report

Flavonifractor plautii bloodstream infection in an asplenic patient with infectious colitis

verfasst von: Izabella Karpat, Mario Karolyi, Erich Pawelka, Tamara Seitz, Franz Thaller, Christoph Wenisch

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 13-14/2021

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Summary

Background

Flavonifractor plautii is a gram-positive, strictly anaerobic, rod-shaped bacterium. It belongs to the family of Clostridiales, is frequently found in the human gut microbiome and is rarely isolated in other human specimens.

Clinical presentation

We report a case of a bloodstream infection with Flavonifractor plautii following infectious colitis in a 24-year-old asplenic woman with beta thalassemia. The patient presented to our department with diarrhea, fever, and lower abdominal pain for over 1 month. F. plautii was the only organism isolated from blood cultures.

Results

The antimicrobial resistance pattern showed in vitro sensitivity to all antimicrobials used for treatment; however, in vivo treatment with amoxicillin and clavulanic acid failed. After switching to meropenem and metronidazole the patient rapidly recovered.

Conclusion

Asplenia and a damaged intestinal wall might have favored the bloodstream infection. We found similarities in attributes of the affected patients and in treatment patterns between our case and the only three other published case reports.
Literatur
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Metadaten
Titel
Flavonifractor plautii bloodstream infection in an asplenic patient with infectious colitis
verfasst von
Izabella Karpat
Mario Karolyi
Erich Pawelka
Tamara Seitz
Franz Thaller
Christoph Wenisch
Publikationsdatum
27.05.2021
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 13-14/2021
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-021-01877-0

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