Skip to main content
Erschienen in:

18.04.2019 | review article

Acupuncture is effective in improving functional communication in post-stroke aphasia

A systematic review and meta-analysis of randomized controlled trials

verfasst von: Binlong Zhang, Yi Han, Xing Huang, Zhaolan Liu, Shuren Li, Jingling Chang, Ying Gao

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 9-10/2019

Einloggen, um Zugang zu erhalten

Summary

Objective

In this meta-analysis the authors evaluated the effectiveness of acupuncture in improving functional communication and language function in post-stroke aphasia (PSA) patients.

Methods

Data sources: MEDLINE, EMBASE, CENTRAL, AMED, SinoMed, CNKI, VIP, and Wanfang databases, ICTRP, ISRCTN, EUCTR, ClinicalTrials.gov, and Stroke Trials Registries. A search was carried out for randomized controlled trials (RCTs) investigating the effects of acupuncture compared with no treatment or placebo acupuncture on post-stroke aphasia (PSA). The searched records were independently screened by two authors, who extracted the data, and assessed risk of bias of the included RCTs. Data aggregation and risk of bias evaluation were conducted on Review Manager Version 5.3. The protocol was registered in the PROSPERO database (CRD42016037543).

Results

A total of 28 RCTs involving 1747 patients (883 patients in the treatment group and 864 patients in the control group) were included in the quantitative synthesis. The results demonstrated significant effects of acupuncture in improving PSA functional communication (P < 0.00001, standardized mean difference (SMD) = 1.01 [0.81, 1.20]), severity of impairment (P < 0.0001, SMD = 0.64 [0.45, 0.84]), spontaneous speech (P = 0.0002, SMD = 1.51 [0.71, 2.32]), auditory comprehension (P < 0.0001, SMD = 0.84 [0.43, 1.26]), repetition (P < 0.00001, SMD = 1.13 [0.75, 1.52]), naming (P = 0.03, SMD = 0.65 [0.08, 1.23]), reading (P < 0.0001, SMD = 1.56 [0.83, 2.29]), and writing (P = 0.009, SMD = 1.03 [0.25, 1.80]).

Conclusion

Acupuncture seems to be effective in improving PSA functional communication and language function.
Literatur
1.
Zurück zum Zitat Vos T, Abajobir AA, Abate KH, Abbafati C, Abbas KM, Abd-Allah F, GBD 2016 Disease and Injury Incidence and Prevalence Collaborators, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390:1211–59.CrossRef Vos T, Abajobir AA, Abate KH, Abbafati C, Abbas KM, Abd-Allah F, GBD 2016 Disease and Injury Incidence and Prevalence Collaborators, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390:1211–59.CrossRef
2.
Zurück zum Zitat Davis GA. Aphasiology: Disorders and clinical practice. 2nd ed. Boston: Pearson; 2006. Davis GA. Aphasiology: Disorders and clinical practice. 2nd ed. Boston: Pearson; 2006.
3.
Zurück zum Zitat Gottesman RF, Hillis AE. Predictors and assessment of cognitive dysfunction resulting from ischaemic stroke. Lancet Neurol. 2010;9:895–905.CrossRef Gottesman RF, Hillis AE. Predictors and assessment of cognitive dysfunction resulting from ischaemic stroke. Lancet Neurol. 2010;9:895–905.CrossRef
4.
Zurück zum Zitat Inatomi Y, Yonehara T, Omiya S, Hashimoto Y, Hirano T, Uchino M. Aphasia during the acute phase in ischemic stroke. Cerebrovasc Dis. 2008;25:316–23.CrossRef Inatomi Y, Yonehara T, Omiya S, Hashimoto Y, Hirano T, Uchino M. Aphasia during the acute phase in ischemic stroke. Cerebrovasc Dis. 2008;25:316–23.CrossRef
5.
Zurück zum Zitat Engelter ST, Gostynski M, Papa S, et al. Epidemiology of aphasia attributable to first ischemic stroke: Incidence, severity, fluency, etiology, and thrombolysis. Stroke. 2006;37:1379–84.CrossRef Engelter ST, Gostynski M, Papa S, et al. Epidemiology of aphasia attributable to first ischemic stroke: Incidence, severity, fluency, etiology, and thrombolysis. Stroke. 2006;37:1379–84.CrossRef
8.
Zurück zum Zitat Berthier ML, Pulvermuller F, Davila G, Casares NG, Gutierrez A. Drug therapy of post-stroke aphasia: A review of current evidence. Neuropsychol Rev. 2011;21:302–17.CrossRef Berthier ML, Pulvermuller F, Davila G, Casares NG, Gutierrez A. Drug therapy of post-stroke aphasia: A review of current evidence. Neuropsychol Rev. 2011;21:302–17.CrossRef
9.
Zurück zum Zitat Zhang S, Wu B, Liu M, et al. Acupuncture efficacy on ischemic stroke recovery: Multicenter randomized controlled trial in China. Stroke. 2015;46:1301–6.CrossRef Zhang S, Wu B, Liu M, et al. Acupuncture efficacy on ischemic stroke recovery: Multicenter randomized controlled trial in China. Stroke. 2015;46:1301–6.CrossRef
10.
Zurück zum Zitat Peng L, Zhang C, Zhou L, Zuo HX, He XK, Niu YM. Traditional manual acupuncture combined with rehabilitation therapy for shoulder hand syndrome after stroke within the Chinese healthcare system: A systematic review and meta-analysis. Clin Rehabil. 2018;32:429–39.CrossRef Peng L, Zhang C, Zhou L, Zuo HX, He XK, Niu YM. Traditional manual acupuncture combined with rehabilitation therapy for shoulder hand syndrome after stroke within the Chinese healthcare system: A systematic review and meta-analysis. Clin Rehabil. 2018;32:429–39.CrossRef
11.
Zurück zum Zitat Chang J, Gao Y, Li S, Wang J. Effect of acupuncture and speech rehabilitation on motor aphasia after stroke. Chin J Rehabil Theory Pract. 2010;16(1):58–9. Chang J, Gao Y, Li S, Wang J. Effect of acupuncture and speech rehabilitation on motor aphasia after stroke. Chin J Rehabil Theory Pract. 2010;16(1):58–9.
12.
Zurück zum Zitat Jiang H, Zhou Y, Liang X. Integrative analysis of clinical efficacy in patients with motor aphasia and its impact on the quality of the language of daily life after stroke. Chin Arch Tradit Chin Med. 2015;33:1235–7. Jiang H, Zhou Y, Liang X. Integrative analysis of clinical efficacy in patients with motor aphasia and its impact on the quality of the language of daily life after stroke. Chin Arch Tradit Chin Med. 2015;33:1235–7.
13.
Zurück zum Zitat Wang M. Combining scalp acupuncture, tongue acupuncture and language rehabilitation for post-acute-stroke aphasia. J Bethune Med Sci. 2016;14:740–1. Wang M. Combining scalp acupuncture, tongue acupuncture and language rehabilitation for post-acute-stroke aphasia. J Bethune Med Sci. 2016;14:740–1.
14.
Zurück zum Zitat Glass GV. Research, primary secondary and Meta-analysis. Educ Res. 1976;5:3–8.CrossRef Glass GV. Research, primary secondary and Meta-analysis. Educ Res. 1976;5:3–8.CrossRef
15.
Zurück zum Zitat Armstrong E, Ferguson A. Language, meaning, context, and functional communication. Aphasiology. 2010;24:480–96.CrossRef Armstrong E, Ferguson A. Language, meaning, context, and functional communication. Aphasiology. 2010;24:480–96.CrossRef
17.
Zurück zum Zitat Gialanella B. Aphasia assessment and functional outcome prediction in patients with aphasia after stroke. J Neurol. 2011;258:343–9.CrossRef Gialanella B. Aphasia assessment and functional outcome prediction in patients with aphasia after stroke. J Neurol. 2011;258:343–9.CrossRef
18.
Zurück zum Zitat Marini A, Andreetta S, del Tin S, Carlomagno S. A multi-level approach to the analysis of narrative language in aphasia. Aphasiology. 2011;25:1372–92.CrossRef Marini A, Andreetta S, del Tin S, Carlomagno S. A multi-level approach to the analysis of narrative language in aphasia. Aphasiology. 2011;25:1372–92.CrossRef
22.
Zurück zum Zitat Liu J, Song KH, You MJ, Son DS, Cho SW, Kim DH. The effect of oculo-acupuncture on recovery from ethylene glycol-induced acute renal injury in dogs. Am J Chin Med. 2007;35:241–50.CrossRef Liu J, Song KH, You MJ, Son DS, Cho SW, Kim DH. The effect of oculo-acupuncture on recovery from ethylene glycol-induced acute renal injury in dogs. Am J Chin Med. 2007;35:241–50.CrossRef
23.
Zurück zum Zitat Zhou Y. The clinical efficacy of scalp electro-acupuncture combined with aphasia (uygur) training system treating for the uygur patients with aphasia. Xinjiang: Xinjiang Medical University; 2015. Zhou Y. The clinical efficacy of scalp electro-acupuncture combined with aphasia (uygur) training system treating for the uygur patients with aphasia. Xinjiang: Xinjiang Medical University; 2015.
24.
Zurück zum Zitat Li A, Xiao W, Wang Y. A follow-up study of poststroke aphasia recovery using acupuncture and donepezfil. J New Med. 2013;44:832–5. Li A, Xiao W, Wang Y. A follow-up study of poststroke aphasia recovery using acupuncture and donepezfil. J New Med. 2013;44:832–5.
26.
Zurück zum Zitat Zhang H. Clinical treatment of apoplectic Aphemia with multi-needle puncture of scalp-points in combination with visual-listening-speech training. Chen Tzu Yen Chiu. 2007;32(3):190–4.PubMed Zhang H. Clinical treatment of apoplectic Aphemia with multi-needle puncture of scalp-points in combination with visual-listening-speech training. Chen Tzu Yen Chiu. 2007;32(3):190–4.PubMed
27.
Zurück zum Zitat Lu Q, Kang B. Clinical observation of acupuncture combined with language rehabilitation for poststroke aphasia. 2010. pp. 179–81. Lu Q, Kang B. Clinical observation of acupuncture combined with language rehabilitation for poststroke aphasia. 2010. pp. 179–81.
28.
Zurück zum Zitat Zheng Q, Yu B, Li Y. Clinical study of acupuncture with language training for aphasia after stroke. J Liaoning Univ Tcm. 2011;13(1):105–7. Zheng Q, Yu B, Li Y. Clinical study of acupuncture with language training for aphasia after stroke. J Liaoning Univ Tcm. 2011;13(1):105–7.
29.
Zurück zum Zitat Xie Z. Clinical Research of acupuncture combined head and body language rehabilitation after stroke motor aphasia. Guangzhou: Guangzhou University of Chinese Medicine; 2014. Xie Z. Clinical Research of acupuncture combined head and body language rehabilitation after stroke motor aphasia. Guangzhou: Guangzhou University of Chinese Medicine; 2014.
30.
Zurück zum Zitat Hu X, Zhou W. Clinical Observation of puncturing meridians therapy for post stroke ganglion aphasia. Lishizhen Med Materia Medica Res. 2010;21:2084–2085. Hu X, Zhou W. Clinical Observation of puncturing meridians therapy for post stroke ganglion aphasia. Lishizhen Med Materia Medica Res. 2010;21:2084–2085.
31.
Zurück zum Zitat Li Y. Clinical research on aphasia from apoplexy treated by acupuncture needling integrated with language training. Hunan: Hunan University of Chinese Medicine; 2009. Li Y. Clinical research on aphasia from apoplexy treated by acupuncture needling integrated with language training. Hunan: Hunan University of Chinese Medicine; 2009.
32.
Zurück zum Zitat Sun Q, Ji X, Cui Z. Observation on the therapeutic effect of scalp acupuncture, plum-blossom needle combined with speech rehabilitation training on aphasia of ischemic apoplexy. World J Acupunct Moxibustion. 2010;20:13–8. Sun Q, Ji X, Cui Z. Observation on the therapeutic effect of scalp acupuncture, plum-blossom needle combined with speech rehabilitation training on aphasia of ischemic apoplexy. World J Acupunct Moxibustion. 2010;20:13–8.
33.
Zurück zum Zitat Wang G, Liu L, Li L, Dong B, Wang S. Clinic observation on motor aphasia after stroke by acupuncture and psychological intervention combined with rehabilitation training. J Liaoning Univ Tcm. 2015;17:5–8.CrossRef Wang G, Liu L, Li L, Dong B, Wang S. Clinic observation on motor aphasia after stroke by acupuncture and psychological intervention combined with rehabilitation training. J Liaoning Univ Tcm. 2015;17:5–8.CrossRef
34.
Zurück zum Zitat Zhou Y, Song J, Li X, Li X. Sichong point Yinzhong Yinyang acupuncture combined with Schuell language training for aphasia after Ischemic stroke. J Clin Acupunct Moxibustion. 2015;32(7):26–8. Zhou Y, Song J, Li X, Li X. Sichong point Yinzhong Yinyang acupuncture combined with Schuell language training for aphasia after Ischemic stroke. J Clin Acupunct Moxibustion. 2015;32(7):26–8.
35.
Zurück zum Zitat Yang L, Guo Y. Clinical study of scalp electroacupuncture combined with language training on post-stroke aphasia patients. Chin J Rehabil Med. 2017;32:305–8. Yang L, Guo Y. Clinical study of scalp electroacupuncture combined with language training on post-stroke aphasia patients. Chin J Rehabil Med. 2017;32:305–8.
36.
Zurück zum Zitat Tan J, Zhang H, Han G, Ai K, Deng S. Acupuncture for aphasia: A retrospective analysis of clinical literature. Zhongguo Zhen Jiu. 2016;36:431–6.PubMed Tan J, Zhang H, Han G, Ai K, Deng S. Acupuncture for aphasia: A retrospective analysis of clinical literature. Zhongguo Zhen Jiu. 2016;36:431–6.PubMed
37.
Zurück zum Zitat Zhang Y, Fu L, Zhu Y, Xue P. Acupuncture treatment for aphasia after stroke: A systematic review. J Clin Acupunct Moxibustion. 2014;31:62–5. Zhang Y, Fu L, Zhu Y, Xue P. Acupuncture treatment for aphasia after stroke: A systematic review. J Clin Acupunct Moxibustion. 2014;31:62–5.
38.
Zurück zum Zitat Pan D. A meta analysis of acupuncture for post stroke aphasia. Shandong Med J. 2013;53:87–9. Pan D. A meta analysis of acupuncture for post stroke aphasia. Shandong Med J. 2013;53:87–9.
39.
Zurück zum Zitat Sun Y, Xue SA, Zuo Z. Acupuncture therapy on apoplectic aphasia rehabilitation. J Tradit Chin Med. 2012;32:314–21.CrossRef Sun Y, Xue SA, Zuo Z. Acupuncture therapy on apoplectic aphasia rehabilitation. J Tradit Chin Med. 2012;32:314–21.CrossRef
40.
Zurück zum Zitat Pang Y, Wu LB, Liu DH. Acupuncture therapy for apoplectic aphasia: A systematic review. Zhongguo Zhen Jiu. 2010;30:612–6.PubMed Pang Y, Wu LB, Liu DH. Acupuncture therapy for apoplectic aphasia: A systematic review. Zhongguo Zhen Jiu. 2010;30:612–6.PubMed
41.
Zurück zum Zitat Li YF, Kurabayashi Y, Zhao SH, et al. Meta analysis on acupuncture treatment of aphasia. zhen Ci Yan Jiu. 2010;35:468–73.PubMed Li YF, Kurabayashi Y, Zhao SH, et al. Meta analysis on acupuncture treatment of aphasia. zhen Ci Yan Jiu. 2010;35:468–73.PubMed
42.
Zurück zum Zitat Jiang Y, Zhou Y, Wang B, Tang S, Niu W. The efficacy of acupuncture on treating aphasia following stroke: A Meta-analysis. Xinjiang Med J. 2016;46:1237–41. Jiang Y, Zhou Y, Wang B, Tang S, Niu W. The efficacy of acupuncture on treating aphasia following stroke: A Meta-analysis. Xinjiang Med J. 2016;46:1237–41.
43.
Zurück zum Zitat Gao S. Aphasia. Beijing: Peking University Medical Press; 2005. Gao S. Aphasia. Beijing: Peking University Medical Press; 2005.
44.
Zurück zum Zitat Gao S, Zhe Y, Shi S. The research of the standardization of aphasia battery of Chinese. Chin Ment Health J. 1992;6(3):125–8. Gao S, Zhe Y, Shi S. The research of the standardization of aphasia battery of Chinese. Chin Ment Health J. 1992;6(3):125–8.
45.
Zurück zum Zitat Dong B. Study of the combination of scalp acupuncture and body acupuncture in treating acute ischemic stroke patients with Broca aphasia. Beijing: Beijing University of Chinese Medicine; 2011. Dong B. Study of the combination of scalp acupuncture and body acupuncture in treating acute ischemic stroke patients with Broca aphasia. Beijing: Beijing University of Chinese Medicine; 2011.
46.
Zurück zum Zitat Gu Y. Clinical research on acupuncture in Jinjinyuye point with speech therapy for Broca aphasia following stroke. Fujian: Fujian University of Chinese Medicine; 2009. Gu Y. Clinical research on acupuncture in Jinjinyuye point with speech therapy for Broca aphasia following stroke. Fujian: Fujian University of Chinese Medicine; 2009.
48.
Zurück zum Zitat Winstein CJ, Stein J, Arena R, et al. Guidelines for adult stroke rehabilitation and recovery: A guideline for Healthcare professionals from the American heart association/American stroke association. Stroke. 2016;47:e98–e169.CrossRef Winstein CJ, Stein J, Arena R, et al. Guidelines for adult stroke rehabilitation and recovery: A guideline for Healthcare professionals from the American heart association/American stroke association. Stroke. 2016;47:e98–e169.CrossRef
49.
Zurück zum Zitat Zhang T. Chinese guideline of stroke rehabilitation. Chin J Rehabil Theory Pract. 2012;18:301–18. Zhang T. Chinese guideline of stroke rehabilitation. Chin J Rehabil Theory Pract. 2012;18:301–18.
50.
Zurück zum Zitat Wu Q, Hu X, Wen X, Li F, Fu W. Clinical study of acupuncture treatment on motor aphasia after stroke. Technol Health Care. 2016;24(Suppl 2):691–6.CrossRef Wu Q, Hu X, Wen X, Li F, Fu W. Clinical study of acupuncture treatment on motor aphasia after stroke. Technol Health Care. 2016;24(Suppl 2):691–6.CrossRef
51.
Zurück zum Zitat Tao J, Fang Y, Wu Z, et al. Community-applied research of a traditional Chinese medicine rehabilitation scheme on Broca’s aphasia after stroke: Study protocol for a randomized controlled trial. Trials. 2014;15:290.CrossRef Tao J, Fang Y, Wu Z, et al. Community-applied research of a traditional Chinese medicine rehabilitation scheme on Broca’s aphasia after stroke: Study protocol for a randomized controlled trial. Trials. 2014;15:290.CrossRef
52.
Zurück zum Zitat Chang J, Zhang H, Tan Z, Xiao J, Li S, Gao Y. Effect of electroacupuncture in patients with post-stroke motor aphasia: Neurolinguistic and neuroimaging characteristics. Wien Klin Wochenschr. 2017;129:102–9.CrossRef Chang J, Zhang H, Tan Z, Xiao J, Li S, Gao Y. Effect of electroacupuncture in patients with post-stroke motor aphasia: Neurolinguistic and neuroimaging characteristics. Wien Klin Wochenschr. 2017;129:102–9.CrossRef
53.
Zurück zum Zitat Li G, Yang ES. An fMRI study of acupuncture-induced brain activation of aphasia stroke patients. complementary Ther Med. 2011;19(Suppl 1):S49–59.CrossRef Li G, Yang ES. An fMRI study of acupuncture-induced brain activation of aphasia stroke patients. complementary Ther Med. 2011;19(Suppl 1):S49–59.CrossRef
54.
Zurück zum Zitat Chau AC, Fai Cheung RT, Jiang X, Au-Yeung PK, Li LS. An fMRI study showing the effect of acupuncture in chronic stage stroke patients with aphasia. J Acupunct Meridian Stud. 2010;3:53–7.CrossRef Chau AC, Fai Cheung RT, Jiang X, Au-Yeung PK, Li LS. An fMRI study showing the effect of acupuncture in chronic stage stroke patients with aphasia. J Acupunct Meridian Stud. 2010;3:53–7.CrossRef
55.
Zurück zum Zitat Xian Y, Chen J. Effect of acupuncture plus language function training on language function in patients with post-stroke aphasia. J China Prescr Drug. 2016;14:1–2. Xian Y, Chen J. Effect of acupuncture plus language function training on language function in patients with post-stroke aphasia. J China Prescr Drug. 2016;14:1–2.
56.
Zurück zum Zitat Wang N, Li Y. Therapeutic observation of cluster needling at anterior oblique line of vertex-temporal plus speech training for motor aphasia after cerebral infarction. shanghai J Acu-mox. 2015;34:412–4. Wang N, Li Y. Therapeutic observation of cluster needling at anterior oblique line of vertex-temporal plus speech training for motor aphasia after cerebral infarction. shanghai J Acu-mox. 2015;34:412–4.
57.
Zurück zum Zitat Shao B. Clinical research on acupuncture in root and end and appearance and substance of kidney meridian associated with language training for Broca aphasia following the stroke. Fujian: Fujian University of Chinese Medicine; 2012. Shao B. Clinical research on acupuncture in root and end and appearance and substance of kidney meridian associated with language training for Broca aphasia following the stroke. Fujian: Fujian University of Chinese Medicine; 2012.
58.
Zurück zum Zitat Wang L, Liu S, Liu M. Post-stroke speech disorder treated with acupuncture and psychological intervention combined with rehabilitation training: A randomized controlled trial. Chin Acupunct Moxibustion. 2011;31:481–6. Wang L, Liu S, Liu M. Post-stroke speech disorder treated with acupuncture and psychological intervention combined with rehabilitation training: A randomized controlled trial. Chin Acupunct Moxibustion. 2011;31:481–6.
59.
Zurück zum Zitat Luo W, Huang H, Zhu J. Clinical research on Broca aphasia from Ischemic apoplexy treated by acupuncture Associtated with language training. Chin Arch Tradit Chin Med. 2010;29:2451–4. Luo W, Huang H, Zhu J. Clinical research on Broca aphasia from Ischemic apoplexy treated by acupuncture Associtated with language training. Chin Arch Tradit Chin Med. 2010;29:2451–4.
60.
Zurück zum Zitat Mu J, Fu L, Lu Y. Clinical observation on the Xingnao Kaiqiao acupuncture plus language rehabilitation training for motor aphasia caused by cerebral infarction: A report of 30 cases. J Tradit Chin Med. 2010;30:428–31. Mu J, Fu L, Lu Y. Clinical observation on the Xingnao Kaiqiao acupuncture plus language rehabilitation training for motor aphasia caused by cerebral infarction: A report of 30 cases. J Tradit Chin Med. 2010;30:428–31.
61.
Zurück zum Zitat Wu F, Yang W, Zhao N. Influence of Tongli acupuncture combined with speech function rehabilitation training on speech Functionon in patients with motor aphasia after cerebral infarction. Chin J Integr Med Cardio-cerebrovascular Dis. 2010;8:290–2. Wu F, Yang W, Zhao N. Influence of Tongli acupuncture combined with speech function rehabilitation training on speech Functionon in patients with motor aphasia after cerebral infarction. Chin J Integr Med Cardio-cerebrovascular Dis. 2010;8:290–2.
62.
Zurück zum Zitat Luo W, Tan J, Huang H. Clinical observation on treatment of cerebral infarction-induced broca aphasia by Tiaoshen Fuyin acupuncture therapy combined with language training. Chin Acupunct Moxibustion. 2008;28(3):171–5. Luo W, Tan J, Huang H. Clinical observation on treatment of cerebral infarction-induced broca aphasia by Tiaoshen Fuyin acupuncture therapy combined with language training. Chin Acupunct Moxibustion. 2008;28(3):171–5.
63.
Zurück zum Zitat Liu L, Guo R, Feng S. Clinical research of acupuncture combined with language rehabilitation for early stroke aphasia. Chin Arch Tradit Chin Med. 2006;24:2256–9. Liu L, Guo R, Feng S. Clinical research of acupuncture combined with language rehabilitation for early stroke aphasia. Chin Arch Tradit Chin Med. 2006;24:2256–9.
64.
Zurück zum Zitat Wang Y. Clinical research on aphasia from apoplexy treated by skull slot needling integrated with language training. Fujian: Fujian University of Chinese Medicine; 2006. Wang Y. Clinical research on aphasia from apoplexy treated by skull slot needling integrated with language training. Fujian: Fujian University of Chinese Medicine; 2006.
65.
Zurück zum Zitat Zhang B. Treating Nonfluent aphasia following stroke by scalp acupuncture with speech therapy. Fujian: Fujian University of Chinese Medicine; 2005. Zhang B. Treating Nonfluent aphasia following stroke by scalp acupuncture with speech therapy. Fujian: Fujian University of Chinese Medicine; 2005.
Metadaten
Titel
Acupuncture is effective in improving functional communication in post-stroke aphasia
A systematic review and meta-analysis of randomized controlled trials
verfasst von
Binlong Zhang
Yi Han
Xing Huang
Zhaolan Liu
Shuren Li
Jingling Chang
Ying Gao
Publikationsdatum
18.04.2019
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 9-10/2019
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-019-1478-5