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Erschienen in: Wiener klinische Wochenschrift 3-4/2014

01.02.2014 | original article

The role of intraoperative ultrasound in breast-conserving surgery of nonpalpable breast cancer

verfasst von: MD Nina Čas Sikošek, MD Andraž Dovnik, MD, PhD Darja Arko, MD, PhD Iztok Takač

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 3-4/2014

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Summary

Objective

This retrospective study was undertaken to evaluate the role of intraoperative ultrasound in breast-conserving surgery of nonpalpable breast cancer.

Methods

The data about 125 patients with preoperatively diagnosed breast cancer operated with the help of intraoperative ultrasound between January 2009 and December 2012 were retrospectively analyzed.

Results

The mean volume of the excised tissue was 42.1 cm3 (± 22.0 cm3). Immediate re-excision after ultrasound examination of the excised tissue was performed in 27 patients (21.6 %). Secondary procedure owing to positive histological margins was necessary only in four patients (3.2 %).

Conclusions

Intraoperative ultrasound offers some advantages in comparison with other localization techniques for nonpalpable breast cancer surgery.

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Literatur
1.
Zurück zum Zitat Harlow SP, Krag DN, Ames SE, Weaver DL. Intraoperative ultrasound localization to guide surgical excision of nonpalpable breast carcinoma. J Am Coll Surg. 1999;189:241–6. PubMedCrossRef Harlow SP, Krag DN, Ames SE, Weaver DL. Intraoperative ultrasound localization to guide surgical excision of nonpalpable breast carcinoma. J Am Coll Surg. 1999;189:241–6. PubMedCrossRef
2.
Zurück zum Zitat Tafra L, Essner R, Brenner RJ, Giuliano AE. Nonpalpable versus palpable invasive breast tumors treated with breast-conserving surgical management. Am Surg. 1996;62:395–9. PubMed Tafra L, Essner R, Brenner RJ, Giuliano AE. Nonpalpable versus palpable invasive breast tumors treated with breast-conserving surgical management. Am Surg. 1996;62:395–9. PubMed
4.
Zurück zum Zitat Mannell A. Breast-conserving therapy in breast cancer patients—a 12-year experience. S Afr J Surg. 2005;43:28–30. PubMed Mannell A. Breast-conserving therapy in breast cancer patients—a 12-year experience. S Afr J Surg. 2005;43:28–30. PubMed
5.
Zurück zum Zitat Fortunato L, Penteriani R, Farina M, Vitelli CE, Piro FR. Intraoperative ultrasound is an effective and preferable technique to localize non-palpable breast tumors. Eur J Surg Oncol. 2008;34:1289–92. PubMedCrossRef Fortunato L, Penteriani R, Farina M, Vitelli CE, Piro FR. Intraoperative ultrasound is an effective and preferable technique to localize non-palpable breast tumors. Eur J Surg Oncol. 2008;34:1289–92. PubMedCrossRef
6.
Zurück zum Zitat Bouton ME, Wilhelmson KL, Komenaka IK. Intraoperative ultrasound can facilitate the wire guided breast procedure for mammographic abnormalities. Am Surg. 2011;77:640–6. PubMed Bouton ME, Wilhelmson KL, Komenaka IK. Intraoperative ultrasound can facilitate the wire guided breast procedure for mammographic abnormalities. Am Surg. 2011;77:640–6. PubMed
7.
Zurück zum Zitat Abrahamson PE, Dunlap LA, Amamoo MA, Schell MJ, Braeuning MP, Pisano ED. Factors predicting successful needle-localized breast biopsy. Acad Radiol. 2003;10:601–6. PubMedCrossRef Abrahamson PE, Dunlap LA, Amamoo MA, Schell MJ, Braeuning MP, Pisano ED. Factors predicting successful needle-localized breast biopsy. Acad Radiol. 2003;10:601–6. PubMedCrossRef
8.
Zurück zum Zitat De Cicco C, Pizzamiglio, Trifirò G, et al. Radioguided occult lesion localisation (ROLL) and surgical biopsy in breast cancer. Technical aspects. Q J Nucl Med. 2002;46:145–51. PubMed De Cicco C, Pizzamiglio, Trifirò G, et al. Radioguided occult lesion localisation (ROLL) and surgical biopsy in breast cancer. Technical aspects. Q J Nucl Med. 2002;46:145–51. PubMed
9.
Zurück zum Zitat Medina-Franco H, Abarca-Pérez L, García-Alvarez MN, Ulloa-Gómez JL, Romero-Trejo C, Sepúlveda-Méndez J. Radioguided occult lesion localization (ROLL) versus wire-guided lumpectomy for non-palpable breast lesions: a randomized prospective evaluation. J Surg Oncol. 2008;97:108–11. PubMedCrossRef Medina-Franco H, Abarca-Pérez L, García-Alvarez MN, Ulloa-Gómez JL, Romero-Trejo C, Sepúlveda-Méndez J. Radioguided occult lesion localization (ROLL) versus wire-guided lumpectomy for non-palpable breast lesions: a randomized prospective evaluation. J Surg Oncol. 2008;97:108–11. PubMedCrossRef
10.
Zurück zum Zitat Pilkington Woll JP, Cortés Romera M, García Vicente AM, et al. Impact of radioguided occult lesion localization on the correct excision of malignant breast lesions: effect of histology and tumor size. Ann Nucl Med. 2011;25:197–203. Pilkington Woll JP, Cortés Romera M, García Vicente AM, et al. Impact of radioguided occult lesion localization on the correct excision of malignant breast lesions: effect of histology and tumor size. Ann Nucl Med. 2011;25:197–203.
11.
12.
Zurück zum Zitat Barentsz MW, van Dalen T, Gobardhan PD, et al. Intraoperative ultrasound guidance for excision of non-palpable invasive breast cancer: a hospital-based series and an overview of the literature. Breast Cancer Res Treat. 2012;135:209–19. PubMedCrossRef Barentsz MW, van Dalen T, Gobardhan PD, et al. Intraoperative ultrasound guidance for excision of non-palpable invasive breast cancer: a hospital-based series and an overview of the literature. Breast Cancer Res Treat. 2012;135:209–19. PubMedCrossRef
13.
Zurück zum Zitat Yu CC, Chiang KC, Kuo WL, Shen SC, Lo YF, Chen SC. Low re-excision rate for positive margins in patients treated with ultrasound-guided breast-conserving surgery. [published online ahead of print January 17, 2013]. Breast. doi:10.1016/j.breast.2012.12.019. Yu CC, Chiang KC, Kuo WL, Shen SC, Lo YF, Chen SC. Low re-excision rate for positive margins in patients treated with ultrasound-guided breast-conserving surgery. [published online ahead of print January 17, 2013]. Breast. doi:10.1016/j.breast.2012.12.019.
14.
Zurück zum Zitat Krekel NM, Zonderhuis BM, Stockmann HB, et al. A comparison of three methods for nonpalpable breast cancer excision. Eur J Surg Oncol. 2011;37:109–15. PubMedCrossRef Krekel NM, Zonderhuis BM, Stockmann HB, et al. A comparison of three methods for nonpalpable breast cancer excision. Eur J Surg Oncol. 2011;37:109–15. PubMedCrossRef
15.
Zurück zum Zitat Haid A, Knauer M, Dunzinger S, et al. Intra-operative sonography: a valuable aid during breast-conserving surgery for occult breast cancer. Ann Surg Oncol. 2007;14:3090–101. PubMedCrossRef Haid A, Knauer M, Dunzinger S, et al. Intra-operative sonography: a valuable aid during breast-conserving surgery for occult breast cancer. Ann Surg Oncol. 2007;14:3090–101. PubMedCrossRef
16.
Zurück zum Zitat Park CC, Mitsumori M, Nixon A, et al. Outcome at 8 years after breast-conserving surgery and radiation therapy for invasive breast cancer: influence of margin status and systemic therapy on local recurrence. J Clin Oncol. 2000;18:1668–75. PubMed Park CC, Mitsumori M, Nixon A, et al. Outcome at 8 years after breast-conserving surgery and radiation therapy for invasive breast cancer: influence of margin status and systemic therapy on local recurrence. J Clin Oncol. 2000;18:1668–75. PubMed
17.
Zurück zum Zitat Corsetti V, Ferrari A, Ghirardi M, et al. Role of ultrasonography in detecting mammographically occult breast carcinoma in women with dense breasts. Radiol Med. 2006;111:440–8. PubMedCrossRef Corsetti V, Ferrari A, Ghirardi M, et al. Role of ultrasonography in detecting mammographically occult breast carcinoma in women with dense breasts. Radiol Med. 2006;111:440–8. PubMedCrossRef
18.
Zurück zum Zitat Shin HC, Han W, Moon HG, et al. Nomogram for predicting positive resection margins after breast-conserving surgery. Breast Cancer Res Treat. 2012;13:1115–23. CrossRef Shin HC, Han W, Moon HG, et al. Nomogram for predicting positive resection margins after breast-conserving surgery. Breast Cancer Res Treat. 2012;13:1115–23. CrossRef
19.
Zurück zum Zitat Menes TS, Tartter PI, Bleiweiss I, Godbold JH, Estabrook A, Smith SR. The consequence of multiple re-excisions to obtain clear lumpectomy margins in breast cancer patients. Ann Surg Oncol. 2005;12:881–5. PubMedCrossRef Menes TS, Tartter PI, Bleiweiss I, Godbold JH, Estabrook A, Smith SR. The consequence of multiple re-excisions to obtain clear lumpectomy margins in breast cancer patients. Ann Surg Oncol. 2005;12:881–5. PubMedCrossRef
20.
Zurück zum Zitat Cochrane RA, Valasiadou P, Wilson AR, Al-Ghazal SK, Macmillan RD. Cosmesis and satisfaction after breast-conserving surgery correlates with the percentage of breast volume excised. Br J Surg. 2003;90:1505–9. PubMedCrossRef Cochrane RA, Valasiadou P, Wilson AR, Al-Ghazal SK, Macmillan RD. Cosmesis and satisfaction after breast-conserving surgery correlates with the percentage of breast volume excised. Br J Surg. 2003;90:1505–9. PubMedCrossRef
21.
Zurück zum Zitat Rahusen FD, Bremers AJ, Fabry HF, van Amerongen AH, Boom RP, Meijer S. Ultrasound-guided lumpectomy of nonpalpable breast cancer versus wire-guided resection: a randomized clinical trial. Ann Surg Oncol. 2002;9:994–8. PubMedCrossRef Rahusen FD, Bremers AJ, Fabry HF, van Amerongen AH, Boom RP, Meijer S. Ultrasound-guided lumpectomy of nonpalpable breast cancer versus wire-guided resection: a randomized clinical trial. Ann Surg Oncol. 2002;9:994–8. PubMedCrossRef
22.
Zurück zum Zitat Snider HC Jr, Morrison DG. Intraoperative ultrasound localization of nonpalpable breast lesions. Ann Surg Oncol. 1999;6:308–14. PubMedCrossRef Snider HC Jr, Morrison DG. Intraoperative ultrasound localization of nonpalpable breast lesions. Ann Surg Oncol. 1999;6:308–14. PubMedCrossRef
23.
Zurück zum Zitat Zgajnar J, Hocevar M, Frkovic-Grazio S, Hertl K, Schweiger E, Besic N. Radioguided occult lesion localization (ROLL) of the nonpalpable breast lesions. Neoplasma 2004;51:385–9. PubMed Zgajnar J, Hocevar M, Frkovic-Grazio S, Hertl K, Schweiger E, Besic N. Radioguided occult lesion localization (ROLL) of the nonpalpable breast lesions. Neoplasma 2004;51:385–9. PubMed
24.
Zurück zum Zitat Besic N, Kramaric A, Podnar B, et al. Factors correlated to successful surgical treatment of 181 non-palpable invasive breast carcinomas. Breast. 2009;18:294–8. PubMedCrossRef Besic N, Kramaric A, Podnar B, et al. Factors correlated to successful surgical treatment of 181 non-palpable invasive breast carcinomas. Breast. 2009;18:294–8. PubMedCrossRef
25.
Zurück zum Zitat Bennett IC, Greenslade J, Chiam H. Intraoperative ultrasound-guided excision of nonpalpable breast lesions. World J Surg. 2005;29:369–74. PubMedCrossRef Bennett IC, Greenslade J, Chiam H. Intraoperative ultrasound-guided excision of nonpalpable breast lesions. World J Surg. 2005;29:369–74. PubMedCrossRef
26.
Zurück zum Zitat Ngô C, Pollet AG, Laperrelle J, et al. Intraoperative ultrasound localization of nonpalpable breast cancers. Ann Surg Oncol. 2007;14:2485–9. PubMedCrossRef Ngô C, Pollet AG, Laperrelle J, et al. Intraoperative ultrasound localization of nonpalpable breast cancers. Ann Surg Oncol. 2007;14:2485–9. PubMedCrossRef
27.
Zurück zum Zitat Ramos M, Díaz JC, Ramos T, et al. Ultrasound-guided excision combined with intraoperative assessment of gross macroscopic margins decreases the rate of reoperations for non-palpable invasive breast cancer [published online ahead of print October 27, 2012]. Breast. doi:10.1016/j.breast.2012.10.006. Ramos M, Díaz JC, Ramos T, et al. Ultrasound-guided excision combined with intraoperative assessment of gross macroscopic margins decreases the rate of reoperations for non-palpable invasive breast cancer [published online ahead of print October 27, 2012]. Breast. doi:10.1016/j.breast.2012.10.006.
28.
Zurück zum Zitat Fisher CS, Mushawah FA, Cyr AE, Gao F, Margenthaler JA. Ultrasound-guided lumpectomy for palpable breast cancers. Ann Surg Oncol. 2011;18:3198–203. PubMedCrossRef Fisher CS, Mushawah FA, Cyr AE, Gao F, Margenthaler JA. Ultrasound-guided lumpectomy for palpable breast cancers. Ann Surg Oncol. 2011;18:3198–203. PubMedCrossRef
29.
Zurück zum Zitat Moore MM, Whitney LA, Cerilli L, et al. Intraoperative ultrasound is associated with clear lumpectomy margins for palpable infiltrating ductal breast cancer. Ann Surg. 2001;233:761–8. PubMedCentralPubMedCrossRef Moore MM, Whitney LA, Cerilli L, et al. Intraoperative ultrasound is associated with clear lumpectomy margins for palpable infiltrating ductal breast cancer. Ann Surg. 2001;233:761–8. PubMedCentralPubMedCrossRef
30.
Zurück zum Zitat Davis KM, Hsu CH, Bouton ME, Wilhelmson KL, Komenaka IK. Intraoperative ultrasound can decrease the re-excision lumpectomy rate in patients with palpable breast cancers. Am Surg. 2011;77:720–5. PubMed Davis KM, Hsu CH, Bouton ME, Wilhelmson KL, Komenaka IK. Intraoperative ultrasound can decrease the re-excision lumpectomy rate in patients with palpable breast cancers. Am Surg. 2011;77:720–5. PubMed
31.
Zurück zum Zitat Olsha O, Shemesh D, Carmon M, et al. Resection margins in ultrasound-guided breast-conserving surgery. Ann Surg Oncol. 2011;18:447–52. PubMedCrossRef Olsha O, Shemesh D, Carmon M, et al. Resection margins in ultrasound-guided breast-conserving surgery. Ann Surg Oncol. 2011;18:447–52. PubMedCrossRef
32.
Zurück zum Zitat Krekel NM, Haloua MH, Lopes Cardozo AM, et al. Intraoperative ultrasound guidance for palpable breast cancer excision (COBALT trial): a multicentre, randomised controlled trial. Lancet Oncol. 2013;14:48–54. PubMedCrossRef Krekel NM, Haloua MH, Lopes Cardozo AM, et al. Intraoperative ultrasound guidance for palpable breast cancer excision (COBALT trial): a multicentre, randomised controlled trial. Lancet Oncol. 2013;14:48–54. PubMedCrossRef
33.
Zurück zum Zitat Krekel NM, Zonderhuis BM, Schreurs HW, et al. Ultrasound-guided breast-sparing surgery to improve cosmetic outcomes and quality of life. A prospective multicentre randomised controlled clinical trial comparing ultrasound-guided surgery to traditional palpation-guided surgery (COBALT trial). BMC Surg. 2011;16:11–8. Krekel NM, Zonderhuis BM, Schreurs HW, et al. Ultrasound-guided breast-sparing surgery to improve cosmetic outcomes and quality of life. A prospective multicentre randomised controlled clinical trial comparing ultrasound-guided surgery to traditional palpation-guided surgery (COBALT trial). BMC Surg. 2011;16:11–8.
Metadaten
Titel
The role of intraoperative ultrasound in breast-conserving surgery of nonpalpable breast cancer
verfasst von
MD Nina Čas Sikošek
MD Andraž Dovnik
MD, PhD Darja Arko
MD, PhD Iztok Takač
Publikationsdatum
01.02.2014
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 3-4/2014
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-013-0470-8