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19.04.2017 | original article

The emergence of vancomycin-resistant Staphylococcus aureus in an intensive care unit in Kerman, Iran

verfasst von: Yasser Fasihi, Fereshteh Saffari, Shahla Mansouri, Dr. Davood Kalantar-Neyestanaki

Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 3-4/2018

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Summary

Methicillin-resistant Staphylococcus aureus (MRSA) is a global threat to public health. This study is the first report of the emergence of vancomycin-resistant MRSA in Kerman, Iran. During a period of 15 months, a total of 205 clinical isolates of S. aureus were collected from three university hospitals affiliated with the Kerman University of Medical Science, Kerman, Iran. Screening of methicillin and vancomycin resistance was carried out by phenotypic methods. The resistance and virulence genes of vancomycin-resistant isolates were detected by polymerase chain reaction (PCR). Staphylococcal cassette chromosome mec (SCCmec) and spa typing were used for molecular typing of vancomycin-resistant isolates. Two S. aureus isolates were considered vancomycin-resistant by phenotypic and genotypic methods. Both isolates showed a minimum inhibitory concentration (MIC) ≥ 64 µg/ml and belonged to SCCmec III and spa type t030. Finding vancomycin-resistant S. aureus (VRSA) isolates represents a serious problem. More stringent infection control policies are recommended to prevent transmission of such life-threatening isolates in the hospital setting.
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Metadaten
Titel
The emergence of vancomycin-resistant Staphylococcus aureus in an intensive care unit in Kerman, Iran
verfasst von
Yasser Fasihi
Fereshteh Saffari
Shahla Mansouri
Dr. Davood Kalantar-Neyestanaki
Publikationsdatum
19.04.2017
Verlag
Springer Vienna
Erschienen in
Wiener Medizinische Wochenschrift / Ausgabe 3-4/2018
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X
DOI
https://doi.org/10.1007/s10354-017-0562-6

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