10.02.2022 | main topic
Natalizumab treatment during pregnancy in multiple sclerosis—clinical and bioethical aspects of an ongoing debate
Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 15-16/2022
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Background
Natalizumab is an approved treatment for relapsing remitting multiple sclerosis; however, its safety during pregnancy is not formally proven.
Case presentation
We report a woman with multiple sclerosis being treated with natalizumab before pregnancy. After withdrawal of natalizumab, she suffered a severe, disabling rebound. In agreement with the patient, natalizumab was restarted during pregnancy. Our patient improved substantially and gave birth to a healthy boy.
Conclusion
Use of natalizumab during pregnancy may be an option in highly active multiple sclerosis.
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