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Erschienen in: Wiener klinische Wochenschrift 11-12/2014

01.06.2014 | case report

Liver hepatotoxicity associated with pantoprazole: a rare case report

verfasst von: Dr. Mehmet Aslan, Yilmaz Celik, Sevdegul Karadas, Sehmus Olmez, Adem Cifci

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 11-12/2014

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Summary

Hepatotoxicity may occasionally develop over the course of treatment with proton pump inhibitors (PPIs). Although skin reactions, interstitial nephritis, pancytopenia, anaphylaxis, and generalized edema have been reported to be associated with PPIs, hepatotoxicity associated with oral pantoprazole is very rare. In this report, we present a case of hepatotoxicity in a 35-year-old man who received pantoprazole (40 mg/day) for acute gastritis. One week after discontinuation of pantoprazole, his liver function began to improve, and the patient gradually fully recovered. Although this toxicity occurs only infrequently, pantoprazole should be considered as a rare hepatotoxic agent in the literature.
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Metadaten
Titel
Liver hepatotoxicity associated with pantoprazole: a rare case report
verfasst von
Dr. Mehmet Aslan
Yilmaz Celik
Sevdegul Karadas
Sehmus Olmez
Adem Cifci
Publikationsdatum
01.06.2014
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 11-12/2014
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-014-0535-3