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Erschienen in: Wiener klinische Wochenschrift 5/2015

01.12.2015 | review article

Advanced therapies of skin injuries

verfasst von: Tina Maver, PhD Asst. Prof. Dr. Uroš Maver, PhD Prof. Karin Stana Kleinschek, PhD Prof. Irena Mlinarič Raščan, PhD, MD Prof. Dragica Maja Smrke

Erschienen in: Wiener klinische Wochenschrift | Sonderheft 5/2015

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Summary

The loss of tissue is still one of the most challenging problems in healthcare. Efficient laboratory expansion of skin tissue to reproduce the skins barrier function can make the difference between life and death for patients with extensive full-thickness burns, chronic wounds, or genetic disorders such as bullous conditions. This engineering has been initiated based on the acute need in the 1980s and today, tissue-engineered skin is the reality. The human skin equivalents are available not only as models for permeation and toxicity screening, but are frequently applied in vivo as clinical skin substitutes. This review aims to introduce the most important recent development in the extensive field of tissue engineering and to describe already approved, commercially available skin substitutes in clinical use.
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Metadaten
Titel
Advanced therapies of skin injuries
verfasst von
Tina Maver
PhD Asst. Prof. Dr. Uroš Maver
PhD Prof. Karin Stana Kleinschek
PhD Prof. Irena Mlinarič Raščan
PhD, MD Prof. Dragica Maja Smrke
Publikationsdatum
01.12.2015
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe Sonderheft 5/2015
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-015-0859-7