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Erschienen in: Wiener klinische Wochenschrift 11-12/2014

01.06.2014 | original article

Is a complete blood cell count useful in determining the prognosis of pulmonary embolism?

verfasst von: Assist. Prof. Hadice Selimoglu Sen, Assist. Prof. Ozlem Abakay, Assoc. Prof. Abdullah Cetin Tanrikulu, Assist. Prof. Cengizhan Sezgi, Assist. Prof. Mahsuk Taylan, Assoc. Prof. Abdurrahman Abakay, Assist. Prof. Halide Kaya, Prof. Abdurrahman Senyigit

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 11-12/2014

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Summary

Background

Pulmonary embolism (PE) is the third cardiovascular cause of hospital admission, following acute coronary syndrome and stroke. Despite high-tech diagnostic methods and new treatment modalities, PEs continue to have a high mortality rate within the first 3 months. This study was designed to assess the additional prognostic value of a complete blood cell count, renal function markers, C-reactive protein, and simplified pulmonary embolism severity index (sPESI) scoring system in PE 100-day mortality.

Materials and methods

The study retrospectively enrolled 208 consecutive patients who were hospitalized with the diagnosis of an acute PE. The patients’ demographic characteristics and clinical and laboratory parameters were recorded from the hospital electronic database and patient’s case notes. The primary end point of the study was an adverse 100-day outcome, defined as death from any cause.

Results

The all-cause mortality in the first 100 days was 14.42 %. The mean age was 57.87 ± 18.17 (range: 16–93) years. We included 79 (38 %) male and 129 (62 %) female individuals. Red cell distribution width (RDW) and sPESI were found to be statistically significant predictors of PE mortality by multivariate regression analysis. On multivariate regression analysis, RDW was associated with a 4.08-fold (95 % confidence interval: 1.229–13.335, P = 0.021) increase in PE mortality.

Conclusion

The results of this study demonstrated that RDW and sPESI may be a useful guide in predicting 100-day mortality. The elevated RDW may alert physicians to possible poor prognosis.
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Metadaten
Titel
Is a complete blood cell count useful in determining the prognosis of pulmonary embolism?
verfasst von
Assist. Prof. Hadice Selimoglu Sen
Assist. Prof. Ozlem Abakay
Assoc. Prof. Abdullah Cetin Tanrikulu
Assist. Prof. Cengizhan Sezgi
Assist. Prof. Mahsuk Taylan
Assoc. Prof. Abdurrahman Abakay
Assist. Prof. Halide Kaya
Prof. Abdurrahman Senyigit
Publikationsdatum
01.06.2014
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 11-12/2014
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-014-0537-1