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01.11.2014 | original article

Central retinal thickness measurement and observance of macular reaction using intraoperative OCT in cataract surgery before and after phacoemulsification

verfasst von: Florian Zeiler, MD, Dr. Marieh Esmaeelpour, PhD, Carl Glittenberg, MD, Prof. Susanne Binder, MD

Erschienen in: Spektrum der Augenheilkunde | Ausgabe 5/2014

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Summary

Purpose:

To demonstrate feasibility of macular cube optical coherence tomography (OCT) scanning and intraoperative central retinal thickness (CRT) measurement with a novel combination of a Carl Zeiss MeditecTM Cirrus HD-OCTTM system adapted to the optical pathway of a Zeiss OPMI VISU 200TM surgical microscope (Intra-OP-OCT) during uneventful small-incision cataract surgery.

Methods/design:

In 50 subjects, 512 × 128 high resolution macular cube scans were performed during surgery, before and immediately after intraocular lens (IOL) implantation. Interobserver variability was calculated from measurements of two observers. In four subgroups of healthy, diabetic, hypertensive and diabetic and hypertensive (both) subjects, measurement reliability and reproducibility is demonstrated.

Results:

Scans of 41 eyes (diabetes n = 11; hypertension n = 15 or both n = 26 and healthy n = 15) with sufficient quality for CRT measurement by both observers. Intra-observer precision was 1 μm, mean interobserver difference was −0.9 μm, with limits of agreement from + 15.1 to − 12.4 μm. Preoperative CRT (mean ± SD, μm) of 210 ± 30 (121–286) increased significantly by 8.2 ± 11.7 to 218 ± 27 (154–296) (p < 0.001). No significant difference was observed between the subgroups (p > 0.05).

Conclusion:

OCT scanning and CRT measurement using Intra-OP-OCT is feasible. A significant increase in CRT of 8 μm immediately after surgery was detected but no difference between the subgroups. Intra-OP-OCT offers novel, highly reproducible information about structural behaviour of the retina during small-incision cataract surgery. Intra-OP-OCT can contribute with precise measurements for better understanding of macular changes following cataract surgery, relevant in patients with macular diseases needing cataract surgery.
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Metadaten
Titel
Central retinal thickness measurement and observance of macular reaction using intraoperative OCT in cataract surgery before and after phacoemulsification
verfasst von
Florian Zeiler, MD
Dr. Marieh Esmaeelpour, PhD
Carl Glittenberg, MD
Prof. Susanne Binder, MD
Publikationsdatum
01.11.2014
Verlag
Springer Vienna
Erschienen in
Spektrum der Augenheilkunde / Ausgabe 5/2014
Print ISSN: 0930-4282
Elektronische ISSN: 1613-7523
DOI
https://doi.org/10.1007/s00717-014-0235-4