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01.10.2016 | original article

The seroprevalence of both hepatitis B and hepatitis C at the first-step health organizations and the difference between the urban and rural areas

verfasst von: Dr. Fatma Kalem, Şerife Yüksekkaya, Metin Başaranoğlu, MD, PhD

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 19-20/2016

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Summary

Background

Hepatitis B virus (HBV) and hepatitis C virus (HCV) are very important infectious agents for public health. The aim of this retrospective study was to assess the seroprevalence of hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (anti-HBs) and anti-HCV test results of patients who admitted to first-step health organizations in central and peripheral districts of Konya, the central region of Turkey during the period 2005–2010.

Methods

In this study, HBsAg, anti-HBs and anti-HCV screening test results of patients who admitted to first-step health organizations in Konya during the period 2005–2010 were retrospectively investigated from the laboratory records. This study was approved by the Konya Health Directorate. All screening tests were performed on the automatic third-generation enzyme-linked immunosorbent assay (MEIA). This immunoassay method was carried out according to the instructions of the manufacturer. Borderline and positive results were retested.

Results

Konya is the largest city of Turkey in terms of surface area and one of the economically developed cities. For HBsAg, anti-HBs and anti-HCV screening, whole test results of 5 years are given in Table 1 and Figure 1. The differences between the urban and rural for HBsAg (p = 0.062 > 0.05) and anti-HCV(p = 0.874 > 0.05) were not statistically significant. Among the markers only for anti-HBs, the difference between the urban and rural was statistically significant (P = 0.042 < 0.05). Of them, 4.15 % were positive for HBsAg, 36.46 % were positive for anti-HBs and 1.16 % were positive for anti-HCV.

Conclusion

In this study, Konya has been evaluated as two regions: central and peripheral. Our study showed us that distribution of the diseases vary from one region to another. We consider that difference in social diversity is one of the factors. These infections are major health problems. So the results of immunodiagnostic tests for HBsAg, anti-HBs and anti-HCV will be useful for guiding control actions and for new preventive strategies.
Literatur
1.
Zurück zum Zitat Alencar Ximenes RA, Pereira LMB, Martelli CMT, Merchán-Hamann E, et al. Methodology of a nationwide cross-sectional survey of prevalence and epidemiological patterns of hepatitis A, B and C infection in Brazil. Cad Saúde Pública, Rio de Janeiro. 2010;26(9):1693–704. Alencar Ximenes RA, Pereira LMB, Martelli CMT, Merchán-Hamann E, et al. Methodology of a nationwide cross-sectional survey of prevalence and epidemiological patterns of hepatitis A, B and C infection in Brazil. Cad Saúde Pública, Rio de Janeiro. 2010;26(9):1693–704.
2.
Zurück zum Zitat Wang YB, Chen EQ, Cui YL, et al. Seroprevalence of hepatitis B virus markers in individuals for physical examination in West China Hospital, China. Eur Rev Med Pharmacol Sci. 2011;15(6):592–6.PubMed Wang YB, Chen EQ, Cui YL, et al. Seroprevalence of hepatitis B virus markers in individuals for physical examination in West China Hospital, China. Eur Rev Med Pharmacol Sci. 2011;15(6):592–6.PubMed
3.
Zurück zum Zitat Zhang H, Li Q, Sun J, Wang C, Gu Q. Seroprevalence and risk factors for hepatitis B infection in an adult population in Northeast China. Int J Med Sci. 2011;8:321–31.CrossRefPubMedPubMedCentral Zhang H, Li Q, Sun J, Wang C, Gu Q. Seroprevalence and risk factors for hepatitis B infection in an adult population in Northeast China. Int J Med Sci. 2011;8:321–31.CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Acar A, Kemahli S, Altunay H, et al. HBV, HCV and HIV seroprevalence among blood donors in Istanbul, Turkey: how effective are the changes in the national blood transfusion policies?. Braz J Infect Dis. 2010;14(1):41–4.CrossRefPubMed Acar A, Kemahli S, Altunay H, et al. HBV, HCV and HIV seroprevalence among blood donors in Istanbul, Turkey: how effective are the changes in the national blood transfusion policies?. Braz J Infect Dis. 2010;14(1):41–4.CrossRefPubMed
6.
Zurück zum Zitat Tonial GC, Passos AM, Livramento L, et al. Hepatitis B marker seroprevalence and vaccination coverage in adolescents in the City of Itajaí, State of Santa Catarina, Southern Brazil, in 2008. Rev Soc Bras Med Trop. 2011:44(4):416–9.CrossRefPubMed Tonial GC, Passos AM, Livramento L, et al. Hepatitis B marker seroprevalence and vaccination coverage in adolescents in the City of Itajaí, State of Santa Catarina, Southern Brazil, in 2008. Rev Soc Bras Med Trop. 2011:44(4):416–9.CrossRefPubMed
7.
Zurück zum Zitat Voigt AR, Neto MS, Spada C, Treitinger A. Seroprevalence of hepatitis B and hepatitis C markers among children and adolescents in the south Brazilian region—metropolitan area of Florianópolis, Santa Catarina. Braz J Infect Dis. 2010;14(1):60–5.PubMed Voigt AR, Neto MS, Spada C, Treitinger A. Seroprevalence of hepatitis B and hepatitis C markers among children and adolescents in the south Brazilian region—metropolitan area of Florianópolis, Santa Catarina. Braz J Infect Dis. 2010;14(1):60–5.PubMed
9.
Zurück zum Zitat Weinbaum CM, Mast EE, Ward JW. Recommendations for identification and public health management of persons with chronic hepatitis B virus infection. Hepatology. 2009;49:35–44.CrossRef Weinbaum CM, Mast EE, Ward JW. Recommendations for identification and public health management of persons with chronic hepatitis B virus infection. Hepatology. 2009;49:35–44.CrossRef
10.
Zurück zum Zitat Liaw YF. Management of patients with chronic hepatitis B. J Gastroenterol Hepatol. 2002;17:406–8.CrossRefPubMed Liaw YF. Management of patients with chronic hepatitis B. J Gastroenterol Hepatol. 2002;17:406–8.CrossRefPubMed
11.
Zurück zum Zitat Chang MH. Hepatitis B virus infection. Semin Fetal Neonatal Med. 2007;12:160–7. 2002;3:382–8.CrossRefPubMed Chang MH. Hepatitis B virus infection. Semin Fetal Neonatal Med. 2007;12:160–7. 2002;3:382–8.CrossRefPubMed
12.
Zurück zum Zitat Özdemir M, Baykan M. Kan merkezimize başvuran gönüllü donörlerde hepatit B, hepatit C ve HIV seroprevalansı. Selçuk Tıp Derg. 2005;21(1):1–4. Özdemir M, Baykan M. Kan merkezimize başvuran gönüllü donörlerde hepatit B, hepatit C ve HIV seroprevalansı. Selçuk Tıp Derg. 2005;21(1):1–4.
13.
Zurück zum Zitat Kaya S, Arıdoğan BC, Adiloğlu AK, Demirci M. Isparta bölgesi kan donörlerinde HBsAg ve anti-HCV seroprevalansı. S.D.Ü. Tıp Fak Derg. 2005;12:36–8. Kaya S, Arıdoğan BC, Adiloğlu AK, Demirci M. Isparta bölgesi kan donörlerinde HBsAg ve anti-HCV seroprevalansı. S.D.Ü. Tıp Fak Derg. 2005;12:36–8.
14.
Zurück zum Zitat Sakarya S, Tuncer G, Yaşa H, Çiçek C, Kadıköylü G, Yükselen V. Aydın bölgesindeki kan donörlerinde HBsAg ve anti-HCV seroprevalansı ve yaş ve cinsiyetle ilişkisi. KLİMİK Derg 2001;1:22–4. (8) Sakarya S, Tuncer G, Yaşa H, Çiçek C, Kadıköylü G, Yükselen V. Aydın bölgesindeki kan donörlerinde HBsAg ve anti-HCV seroprevalansı ve yaş ve cinsiyetle ilişkisi. KLİMİK Derg 2001;1:22–4. (8)
15.
Zurück zum Zitat Dilek İ, Demir C, Bay A, Akdeniz H, Öner AF. Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. Turk J Hematol. 2007;24:4–7. Dilek İ, Demir C, Bay A, Akdeniz H, Öner AF. Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. Turk J Hematol. 2007;24:4–7.
16.
Zurück zum Zitat Keskinler DÜ. Erzurum Kızılay Kan Merkezi’ne başvuran kan donörlerinin HBV ve HCV yönünden serolojik değerlendirilmesi. İnönü Üniversitesi Tıp Fakültesi Dergisi. 2003;10:195–8. Keskinler DÜ. Erzurum Kızılay Kan Merkezi’ne başvuran kan donörlerinin HBV ve HCV yönünden serolojik değerlendirilmesi. İnönü Üniversitesi Tıp Fakültesi Dergisi. 2003;10:195–8.
17.
Zurück zum Zitat Otağ F, Köksel T. Mersin Tıp Fakültesi Araştırma ve Uygulama Hastanesi Kan Merkezi donörlerinin infeksiyon etkenleri tarama sonuçlarının değerlendirilmesi. MEÜ Tıp Fak Derg. 2002;3:382–8. Otağ F, Köksel T. Mersin Tıp Fakültesi Araştırma ve Uygulama Hastanesi Kan Merkezi donörlerinin infeksiyon etkenleri tarama sonuçlarının değerlendirilmesi. MEÜ Tıp Fak Derg. 2002;3:382–8.
18.
Zurück zum Zitat Temiz H, Gül K. Kan vericilerinin HBsAg, anti-HCV, anti-HIV ve VDRLtest sonuçlarının değerlendirilmesi. Turk J Infect. 2008;22(2):79–82. Temiz H, Gül K. Kan vericilerinin HBsAg, anti-HCV, anti-HIV ve VDRLtest sonuçlarının değerlendirilmesi. Turk J Infect. 2008;22(2):79–82.
19.
Zurück zum Zitat Demiraslan H, Aksöz S. Adıyaman İli Kan Vericilerindeki HBsAg ve Anti- HCV Sıklığının Değerlendirilmesi. Viral Hepatit Dergisi. 2008;13(1):23–6. Demiraslan H, Aksöz S. Adıyaman İli Kan Vericilerindeki HBsAg ve Anti- HCV Sıklığının Değerlendirilmesi. Viral Hepatit Dergisi. 2008;13(1):23–6.
20.
Zurück zum Zitat Turan H, Şerefhanoğlu K, Kanat-Unler G, Arslan H. Konya İlinde Kan Donorlerinde HBsAg ve Anti-HCV Seroprevalansı ve Yaş ve Cinsiyetle İlişkisİ. Klimik Dergisi. 2011;24(1):36–9.CrossRef Turan H, Şerefhanoğlu K, Kanat-Unler G, Arslan H. Konya İlinde Kan Donorlerinde HBsAg ve Anti-HCV Seroprevalansı ve Yaş ve Cinsiyetle İlişkisİ. Klimik Dergisi. 2011;24(1):36–9.CrossRef
21.
Zurück zum Zitat Bhattacharya P, Chandra PC, Datta S, et al. Significant increase in HBV, HCV, HIV and syphilis infections among blood donors in West Bengal, Eastern India 2004–2005: exploratory screening reveals high frequency of occult HBV infection. World J Gastroenterol. 2007;13(27):3730–3.CrossRefPubMedPubMedCentral Bhattacharya P, Chandra PC, Datta S, et al. Significant increase in HBV, HCV, HIV and syphilis infections among blood donors in West Bengal, Eastern India 2004–2005: exploratory screening reveals high frequency of occult HBV infection. World J Gastroenterol. 2007;13(27):3730–3.CrossRefPubMedPubMedCentral
22.
Zurück zum Zitat Gheorghe L, Csiki I, Iacob S, Gheorghe C. The prevalence and risk factors of hepatitis B virus infection in an adult population in Romania: a nationwide survey. Eur J Gastroenterol Hepatol. 2012;10. [Epub ahead of print] Gheorghe L, Csiki I, Iacob S, Gheorghe C. The prevalence and risk factors of hepatitis B virus infection in an adult population in Romania: a nationwide survey. Eur J Gastroenterol Hepatol. 2012;10. [Epub ahead of print]
23.
Zurück zum Zitat Guzelant A, Kurtoğlu MG, Kaya M, Keşli R, Baysal B. Kan vericilerinde ve bir ağız-diş sağlığı merkezi calışanlarında hepatit B, hepatit C ve HIV seroprevalansı ile vericilerde risk faktorlerinin araştırılması. İnfeks Derg. 2008;22(4):189–95. Guzelant A, Kurtoğlu MG, Kaya M, Keşli R, Baysal B. Kan vericilerinde ve bir ağız-diş sağlığı merkezi calışanlarında hepatit B, hepatit C ve HIV seroprevalansı ile vericilerde risk faktorlerinin araştırılması. İnfeks Derg. 2008;22(4):189–95.
24.
Zurück zum Zitat Majori S, Baldo V, Tommasi I, Malizia M, Floreani A, Monteiro G, et al. Hepatitis A, B, and C infection in a community of sub Saharan Immigrants Living in Verona (Italy). J Travel Med. 2008;15(5):323–7.CrossRefPubMed Majori S, Baldo V, Tommasi I, Malizia M, Floreani A, Monteiro G, et al. Hepatitis A, B, and C infection in a community of sub Saharan Immigrants Living in Verona (Italy). J Travel Med. 2008;15(5):323–7.CrossRefPubMed
25.
Zurück zum Zitat Vasilopoulou VA, Hadjichristodoulou C. Migration and viral hepatitis. Viral Hepat. 2008;16:18–9. Vasilopoulou VA, Hadjichristodoulou C. Migration and viral hepatitis. Viral Hepat. 2008;16:18–9.
26.
Zurück zum Zitat El Beltagy KE, Al Balawi IA, Almuneef M, Memish ZA. Prevalence of hepatitis B virus markers among blood donors in a tertiary hospital in Tabuk, northwestern Saudi Arabia. Int J Infect Dis. 2008;12(5):495–9.CrossRefPubMed El Beltagy KE, Al Balawi IA, Almuneef M, Memish ZA. Prevalence of hepatitis B virus markers among blood donors in a tertiary hospital in Tabuk, northwestern Saudi Arabia. Int J Infect Dis. 2008;12(5):495–9.CrossRefPubMed
Metadaten
Titel
The seroprevalence of both hepatitis B and hepatitis C at the first-step health organizations and the difference between the urban and rural areas
verfasst von
Dr. Fatma Kalem
Şerife Yüksekkaya
Metin Başaranoğlu, MD, PhD
Publikationsdatum
01.10.2016
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 19-20/2016
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-015-0745-3

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