Predicting drug sensitivity by 3D cell culture models
- 01.04.2015
- review
Erschienen in:
- Verfasst von
- Arno Amann, MD
- Gabriele Gamerith, MD
- Julia M. Huber, PhD
- Marit Zwierzina, MD
- Wolfgang Hilbe, MD
- Heinz Zwierzina, MD
- Erschienen in
- memo - Magazine of European Medical Oncology | Ausgabe 1/2015
Abstract
Because of recent failures of novel drugs in phase II and III trials innovative in vitro models are needed that may predict drug efficacy in patients. Although, numerous modifications of traditional cell culture and animal models were undertaken significant improvements in cell culture- based drug development have not been achieved. Three-dimensional (3D) cell culture may represents an modern alternative to bridge the gap between 2D cell cultures and animal models.
Anzeige
- Titel
- Predicting drug sensitivity by 3D cell culture models
- Verfasst von
-
Arno Amann, MD
Gabriele Gamerith, MD
Julia M. Huber, PhD
Marit Zwierzina, MD
Wolfgang Hilbe, MD
Heinz Zwierzina, MD
- Publikationsdatum
- 01.04.2015
- Verlag
- Springer Vienna
- Erschienen in
-
memo - Magazine of European Medical Oncology / Ausgabe 1/2015
Print ISSN: 1865-5041
Elektronische ISSN: 1865-5076 - DOI
- https://doi.org/10.1007/s12254-015-0196-6
Dieser Inhalt ist nur sichtbar, wenn du eingeloggt bist und die entsprechende Berechtigung hast.