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01.04.2015 | case report | Ausgabe 1/2015

memo - Magazine of European Medical Oncology 1/2015

High-dose chemotherapy and autologous hematopoietic stem cell transplantation in a myeloma patient with terminal renal failure and hepatitis C with high viral load

Zeitschrift:
memo - Magazine of European Medical Oncology > Ausgabe 1/2015
Autoren:
Priv. Doz. Dr. Niklas Zojer, Michael Gschwantler, Wolfgang Hilbe

Abstract

We report on a patient with multiple myeloma and light-chain induced renal failure, diagnosed with hepatitis C and high viral load in the pre-transplant period. We show that the new hepatitis C virus directed drugs daclatasvir and sofosbuvir can be safely applied concomitantly to high-dose therapy with autologous hematopoietic stem cell transplantation. Liver enzymes remained in the normal range during the transplant and in the post-transplant period.

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