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Erschienen in: Wiener klinische Wochenschrift 13-14/2014

01.07.2014 | original article

May mean platelet volume levels be a predictor in the diagnosis of pelvic inflammatory disease?

verfasst von: Assist. Prof. Dr. Adnan Incebiyik, Ahmet Seker, Mehmet Vural, Nese Gul Hilali, Aysun Camuzcuoglu, Hakan Camuzcuoglu

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 13-14/2014

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Summary

Background

Our aim in this study was to investigate whether mean platelet volume (MPV) value could be used as an early marker to predict pelvic inflammatory disease (PID).

Methods

Overall, 44 patients with PID and 44 healthy women were included in the study. The control group consisted of 44 women who applied to the clinic for a routine gynaecological check-up, without chronic disease or a history of medication use. Owing to the fact that it would affect thrombocyte function, women who have the following conditions were excluded from the study: women who were taking anticoagulant therapy, oral contraceptives, nonsteroid anti-inflammatory medications and who had chronic diseases. The leukocyte count, platelet count, neutrophil ratio and MPV values were collected from PID and the control group. C reactive protein values of patients with PID were also noted.

Results

MPV values in patients with PID were lower than those in the control group. This reduction in MPV is statistically significant when the PID patient group is compared with the control group (p < 0.001). A negative correlation was discovered between platelet count and MPV values (p = 0.019, r = − 0.425). Receiver-operating curve analysis pointed out that MPV has greater area under curve value than neutrophil rate, leukocyte and platelet count (0.73, 0.64, 0.72 and 0.49 respectively).

Conclusion

Since the MPV value was significantly decreased in patients with PID, it may serve as an additional and even more valuable marker than leukocyte count in the diagnosis of PID.
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Metadaten
Titel
May mean platelet volume levels be a predictor in the diagnosis of pelvic inflammatory disease?
verfasst von
Assist. Prof. Dr. Adnan Incebiyik
Ahmet Seker
Mehmet Vural
Nese Gul Hilali
Aysun Camuzcuoglu
Hakan Camuzcuoglu
Publikationsdatum
01.07.2014
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 13-14/2014
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-014-0560-2