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Erschienen in: Wiener klinische Wochenschrift 5/2015

01.12.2015 | original article

Gender-related differences in patients with ST-elevation myocardial infarction

verfasst von: MD, PhD, FESC Prof. Andreja Sinkovič, Stud. med. Nejc Piko, Stud. med. Matevž Privšek, MD Dr. med. Andrej Markota

Erschienen in: Wiener klinische Wochenschrift | Sonderheft 5/2015

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Summary

Background

A decade ago women with ST-elevation myocardial infarction (STEMI) were significantly older than men, with more comorbidities, less likely treated by primary percutaneous coronary intervention (PPCI) and their prognosis was worse. The progress in treatment led to increased survival after STEMI. Our aim was to evaluate the possible current differences between the genders in treatments, mortality and the changes in women over time in STEMI population.

Methods

We retrospectively evaluated 307 STEMI patients (224 men, 83 women), admitted between October 1, 2011 and December 31, 2012 and a historic group of 523 STEMI patients from 2008 to 2009 (361 men, 162 women). Reperfusion strategy was PPCI, combined with aspirin and clopidogrel or prasugrel or ticagrelor and a heparin with glycoprotein receptor IIb/IIIa antagonist or bivalirudin. Between the genders and in women over time we compared clinical data, the use and time to PPCI, in-hospital complications, 30-day and 6-month mortality.

Results

STEMI patients in recent years were treated by PPCI in 94.5 %. Their 30-day mortality was 10.4 % and 6-month mortality 14.7 %. Between the genders we observed mostly nonsignificant differences (age, comorbidities, treatments, in-hospital complications, 30-day and 6-month mortality). Over the last years in women mean age significantly decreased, the use of PPCI significantly increased, the incidence of heart failure and bleedings decreased significantly, but mortalities nonsignificantly.

Conclusion

Women still account for 1/4 of STEMI population, but the gap between the genders in presentation, treatments and outcome in STEMI population is decreasing.
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Metadaten
Titel
Gender-related differences in patients with ST-elevation myocardial infarction
verfasst von
MD, PhD, FESC Prof. Andreja Sinkovič
Stud. med. Nejc Piko
Stud. med. Matevž Privšek
MD Dr. med. Andrej Markota
Publikationsdatum
01.12.2015
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe Sonderheft 5/2015
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-015-0809-4