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Erschienen in:

03.04.2023 | original article

Assessment of diaphragmatic function by ultrasonography in patients with systemic sclerosis and its relation to clinical parameters

A case-control study

verfasst von: Hazal Yakut, PT, PhD, Gamze Yalcinkaya, PT, PhD, Seher Ozyurek, PT, PhD, Sevgi Ozalevli, PT, PhD, Yesim Salik Sengul, PT, PhD, Merih Birlik, MD, PhD

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 19-20/2023

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Summary

Background

Diaphragmatic function can be affected in many diseases and disorders. Although systemic sclerosis (SSc) is a serious connective tissue disease that affects not only the skin but also the pulmonary and musculoskeletal systems, there is insufficient information about diaphragm function.

Aims

To compare the diaphragmatic parameters by ultrasonography (USG) in patients with SSc and healthy individuals and examine the relationship between these parameters and clinical features in patients with SSc.

Methods

This study included 13 patients with SSc and 15 healthy individuals. Muscle thickness (in deep inspiration T_ins and at the end of calm expiration T_exp), changes in thickness (∆T), and thickening fraction at deep breathing were evaluated by USG. Skin thickness, pulmonary function tests, respiratory muscle strength, and the perception of dyspnea were measured as clinical features.

Results

The results of T_exp, T_ins, and ∆T were similar in both groups (p > 0.05), albeit patients in the SSc group had less thickening fraction compared to the control group (79.9 ± 36.7 cm and 103.8 ± 20.6 cm, respectively, p < 0.05). The T_ins, ∆T, and thickening fraction of the diaphragm were associated with skin thickness, pulmonary function test parameters, and respiratory muscle strength (p < 0.05). Besides, there was significant correlation between muscle thickening fraction and perception of dyspnea (p < 0.05).

Conclusion

These results confirm that diaphragm thickness and contractility can be affected in patients with SSc. Therefore, ultrasonographic evaluation of the diaphragm can play a complementary role to pulmonary function test and respiratory muscle strength measurement in the diagnosis and follow-up of patients with SSc.

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Titel: Assessment of diaphragmatic function by ultrasonography in patients with systemic sclerosis and its relation to clinical parameters
A case-control study
verfasst von: Hazal Yakut, PT, PhD
Gamze Yalcinkaya, PT, PhD
Seher Ozyurek, PT, PhD
Sevgi Ozalevli, PT, PhD
Yesim Salik Sengul, PT, PhD
Merih Birlik, MD, PhD
Publikationsdatum: 03.04.2023
Verlag: Springer Vienna
Erschienen in: Wiener klinische Wochenschrift / Ausgabe 19-20/2023
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI: https://doi.org/10.1007/s00508-023-02163-x

Springer Medizin Österreich

Summary

Background

Aims

Methods

Results

Conclusion

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