Skip to main content
main-content

Tipp

Weitere Artikel dieser Ausgabe durch Wischen aufrufen

01.05.2014 | short review | Ausgabe 2/2014

memo - Magazine of European Medical Oncology 2/2014

Treatment results and follow-up after definitive radio-chemotherapy in anal cancer: when to perform biopsies?

Zeitschrift:
memo - Magazine of European Medical Oncology > Ausgabe 2/2014
Autoren:
PD Dr. med. Martina Becker-Schiebe, Wolfgang Hoffmann

Abstract

Management of anal cancer shifted from radical surgical procedures to sphincter-preserving approaches by combined radio-chemotherapy (RCT). Several randomized trials investigated the most appropriate chemotherapy schedule, radiation doses, and treatment techniques. RCT employing 5-fluorouracil (5-FU)/mitomycin C (MMC) remains the standard treatment. Cisplatin was proposed as an alternative drug but failed to improve outcome when given instead of MMC or during maintenance chemotherapy. Currently, studies are ongoing that investigate staging procedures like PET-CT and diagnostic workup processes in treatment follow-up.
This review focuses on treatment results of definitive RCT and factors related to treatment failure. Subsequent follow-up recommendations and the timing of invasive follow-up biopsies are discussed.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 2/2014

memo - Magazine of European Medical Oncology 2/2014 Zur Ausgabe