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Erschienen in: Wiener klinische Wochenschrift Education 3-4/2015

01.12.2015

Therapie der Hepatitis C Virusinfektion

verfasst von: Clarissa Freissmuth, Peter Ferenci, Ao. Univ. Prof. Dr. Harald Hofer

Erschienen in: Wiener klinische Wochenschrift Education | Ausgabe 3-4/2015

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Die Therapie der chronischen Hepatitis C hat in den letzten Jahren große Weiterentwicklungen erfahren. Mittels antiviraler Therapie kann die chronische Virusinfektion mittlerweile in der überwiegenden Mehrzahl der Patienten dauerhaft ausgeheilt werden. Langjährige Säulen der antiviralen Therapie wie Interferon, Steuerung der Therapiedauer nach initialem Ansprechen („response guided therapy“), Bestimmung des IL-28B Genotyps oder die Durchführung einer Leberbiopsie sind mit der Verfügbarkeit von neuen direkt antiviral wirksamen Substanzen zunehmend in den Hintergrund geraten. Mit der Zulassung der direkt antiviralen Substanzen kam es auch zu einer deutlichen Erweiterung des Spektrums der Behandlung von Patienten mit chronischer Hepatitis C, da auch Patienten mit fortgeschrittener Lebererkrankung oder Kontraindikationen gegen Interferon überaus wirkungsvoll und sicher therapiert werden können.
Die Therapie der chronischen Hepatitis C hat in den letzten Jahren große Fortschritte gemacht
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Metadaten
Titel
Therapie der Hepatitis C Virusinfektion
verfasst von
Clarissa Freissmuth
Peter Ferenci
Ao. Univ. Prof. Dr. Harald Hofer
Publikationsdatum
01.12.2015
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift Education / Ausgabe 3-4/2015
Print ISSN: 1863-3579
Elektronische ISSN: 1863-3765
DOI
https://doi.org/10.1007/s11812-015-0072-7