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Cognitive Functioning in Schizophrenia: Leveraging the RDoC Framework

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  • © 2023

Overview

Editors:
  1. Deanna M. Barch

    1. Departments of Psychological and Brain Sciences, Psychiatry, and Radiology, Washington University, Saint Louis, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Jared W. Young

    1. Department of Psychiatry, University of California San Diego, La Jolla, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Equips readers to handle the complexity of cognitive dysfunction in schizophrenia
  • Reviews key recent research revealing mechanisms and potential biomarkers
  • Offers a translational perspective revealing approaches toward treatment development

Part of the book series: Current Topics in Behavioral Neurosciences (CTBN, volume 63)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xii
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  2. The MATRICS Consensus Cognitive Battery: An Update

    • Keith H. Nuechterlein, Michael F. Green, Robert S. Kern
    Pages 1-18

  3. Cognitive [Computational] Neuroscience Test Reliability and Clinical Applications for Serious Mental Illness (CNTRaCS) Consortium: Progress and Future Directions

    • Deanna M. Barch, Megan Ann Boudewyn, Cameron C. Carter, Molly Erickson, Michael J. Frank, James M. Gold et al.
    Pages 19-60

  4. Attention in Schizophrenia

    • Steven J. Luck, James M. Gold
    Pages 61-78

  5. Perceptual Functioning

    • Anne Giersch, Vincent Laprévote
    Pages 79-113

  6. Episodic Memory and Schizophrenia: From Characterization of Relational Memory Impairments to Neuroimaging Biomarkers

    • Delphine Raucher-Chéné, Katie M. Lavigne, Martin Lepage
    Pages 115-136

  7. Working Memory in People with Schizophrenia

    • James M. Gold, Steven J. Luck
    Pages 137-152

  8. Targeting Frontal Gamma Activity with Neurofeedback to Improve Working Memory in Schizophrenia

    • I-Wei Shu, Eric L. Granholm, Fiza Singh
    Pages 153-172

  9. Cognitive Dysfunction as a Risk Factor for Psychosis

    • Nicole R. Karcher, Jaisal Merchant, Jacob Pine, Can Misel Kilciksiz
    Pages 173-203

  10. Environmental Risk Factors and Cognitive Outcomes in Psychosis: Pre-, Perinatal, and Early Life Adversity

    • Emily Lipner, Kathleen J. O’Brien, Madeline R. Pike, Arielle Ered, Lauren M. Ellman
    Pages 205-240

  11. Developmental Manipulation-Induced Changes in Cognitive Functioning

    • Sahith Kaki, Holly DeRosa, Brian Timmerman, Susanne Brummelte, Richard G. Hunter, Amanda C. Kentner
    Pages 241-289

  12. Genetic Influences on Cognitive Dysfunction in Schizophrenia

    • Tiffany A. Greenwood
    Pages 291-314

  13. Using Nonhuman Primate Models to Reverse-Engineer Prefrontal Circuit Failure Underlying Cognitive Deficits in Schizophrenia

    • Mathew V. Chafee
    Pages 315-362

  14. Olfactory Dysfunction in Schizophrenia: Evaluating Olfactory Abilities Across Species

    • Taitum O. Cothren, Christopher J. Evonko, David A. MacQueen
    Pages 363-392

  15. Cholinergic Functioning, Cognition, and Anticholinergic Medication Burden in Schizophrenia

    • Yash B. Joshi
    Pages 393-406

  16. An Update on Treatment of Cognitive Impairment Associated with Schizophrenia

    • William P. Horan, Lauren T. Catalano, Michael F. Green
    Pages 407-436

  17. The Relationship Between Cannabis, Cognition, and Schizophrenia: It’s Complicated

    • Hakan Kayir, Jessica Ruffolo, Patrick McCunn, Jibran Y. Khokhar
    Pages 437-461

  18. Sex Differences in Cognition in Schizophrenia: What We Know and What We Do Not Know

    • Hyun Bin Freeman, Junghee Lee
    Pages 463-474

  19. Rethinking Immunity and Cognition in Clinical High Risk for Psychosis

    • Siân Lowri Griffiths, Rachel Upthegrove, Fabiana Corsi-Zuelli, Bill Deakin
    Pages 475-497
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Keywords

About this book

This book highlights recent research investigating psychological and neural mechanisms contributing to dysfunctional cognition in people with schizophrenia. The work on cognition in schizophrenia from the past 20 years is highlighted, and emphasis throughout the book is placed on utilizing the Research Domain Criterion framework. Thus, the book also covers animals work relevant to schizophrenia that assesses behaviors utilizing the same framework, enabling mechanistic studies and highlighting potential biomarkers of function. The book also includes important areas of research in the field of cognitive function in schizophrenia that have received less attention, such as cognitive side-effects of current treatments and olfactory-based cognition. Altogether, the book provides a translational perspective of the most-up-to-date research on cognition in schizophrenia to-date, but with identification of novel directions for research initiatives..

Editors and Affiliations

  • Departments of Psychological and Brain Sciences, Psychiatry, and Radiology, Washington University, Saint Louis, USA

    Deanna M. Barch

  • Department of Psychiatry, University of California San Diego, La Jolla, USA

    Jared W. Young

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