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Onkologie 30. Juni 2011

Adjuvant chemotherapy in colon carcinoma stages II and III

Adjuvant chemotherapy significantly improves disease-free survival and overall survival in colon cancer. Ongoing clinical trials are evaluating the addition of targeted therapies to standard regimen and the influence of gene expression signature as prognostic and predictive markers for the use of adjuvant chemotherapy. This review will summarize adjuvant therapeutic approaches in stages III and II colon cancer as well as therapeutic options in elderly patients and future developments in the adjuvant setting of colon cancer.

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