A glioblastoma multiforme patient receiving an intracavitary peptide-receptor-radionuclide-therapy with 90Y-DOTA-TOC: a case report
We present the case report of a 23-year-old female patient suffering from a glioblastoma multiforme. Neurosurgery in combination with temozolomide and fractionated external beam radiation, though a fundamental part of therapy, did not prevent progression in this patient. The tumour showed stable regression under the application of peptide-receptor-radionuclide-therapy. Receptor-mediated radionuclide therapy by locally injected 90Y-DOTA-TOC is feasible and well tolerated. This approach represents an attractive strategy for the treatment of locally recurring or progressing glioblastoma.