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Onkologie 31. August 2010

A glioblastoma multiforme patient receiving an intracavitary peptide-receptor-radionuclide-therapy with 90Y-DOTA-TOC: a case report

We present the case report of a 23-year-old female patient suffering from a glioblastoma multiforme. Neurosurgery in combination with temozolomide and fractionated external beam radiation, though a fundamental part of therapy, did not prevent progression in this patient. The tumour showed stable regression under the application of peptide-receptor-radionuclide-therapy. Receptor-mediated radionuclide therapy by locally injected 90Y-DOTA-TOC is feasible and well tolerated. This approach represents an attractive strategy for the treatment of locally recurring or progressing glioblastoma.

D. Putzer, M. Gabriel, E. Donnemiller, H. Kostron, G. Stockhammer, I. J. Virgolini, memo - Magazine of European Medical Oncology 3/2010

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