Skip to main content
SpringerLink
Log in

Der frühe vorzeitige Blasensprung

  • Living reference work entry
  • Latest version View entry history
  • First Online:
Die Geburtshilfe

Part of the book series: Springer Reference Medizin ((SRM))

  • 157 Accesses

Zusammenfassung

Der frühe vorzeitige Blasensprung („preterm premature rupture of membranes“, PPROM, Blasensprung vor 37+0 SSW) betrifft ca. 3 % aller Schwangeren. Ein wesentlicher Risikofaktor ist der Z. n. PPROM. Die Diagnose eines PPROM lässt sich in den meisten Fällen durch eine Spekulumuntersuchung stellen. Bei Unsicherheiten können biochemische Testverfahren eingesetzt werden. Über 50 % aller Patientinnen mit PPROM werden nach einer Woche entbunden. Es besteht die Gefahr der aszendierenden, maternalen Infektion, die in der Folge ein „fetal inflammatory response syndrome“ (FIRS) hervorrufen kann. Bei einem PPROM zwischen 24+0 und 33+6 SSW oder zwischen 22+0 und 23+6 SSW, falls eine Maximaltherapie gewünscht wird, wird ein exspektatives Vorgehen angestrebt. Es erfolgt die antenatale Steroidgabe. Vor 32 SSW kann Magnesium zur fetalen Neuroprotektion appliziert werden. Bei V. a. intrauterine Infektion ist die umgehende Entbindung zu indizieren. Auch im Zeitraum von 34+0 bis 36+6 SSW ist, wie neuere Studien zeigen, ein exspektatives Vorgehen möglich.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

Literatur

  • Abramowicz JS, Sherer DM, Warsof SL, Levy DL (1992) Fetoplacental and uteroplacental Doppler blood flow velocity analysis in premature rupture of membranes. Am J Perinatol 9(5–6):353–356

    Article  CAS  PubMed  Google Scholar 

  • ACOG-Practice-Bulletin (2018) ACOG Practice Bulletin No. 188: prelabor rupture of membranes. Obstet Gynecol 131(1):e14

    Google Scholar 

  • ACOG-Practice-Bulletin (2020) Prelabor rupture of membranes: ACOG Practice Bulletin summary, number 217. Obstet Gynecol 135(3):739–743

    Article  Google Scholar 

  • Alexander JM, Mercer BM, Miodovnik M, Thurnau GR, Goldenberg RL, Das AF, Meis PJ, Moawad AH, Iams JD, VanDorsten JP, Paul RH, Dombrowski MP, Roberts JM, McNellis D (2000) The impact of digital cervical examination on expectantly managed preterm rupture of membranes. Am J Obstet Gynecol 183(4):1003–1007

    Article  CAS  PubMed  Google Scholar 

  • Al-Mandeel H, Alhindi MY, Sauve R (2013) Effects of intentional delivery on maternal and neonatal outcomes in pregnancies with preterm prelabour rupture of membranes between 28 and 34 weeks of gestation: a systematic review and meta-analysis. J Matern Fetal Neonatal Med 26(1):83–89

    Article  PubMed  Google Scholar 

  • Ananth CV, Oyelese Y, Srinivas N, Yeo L, Vintzileos AM (2004) Preterm premature rupture of membranes, intrauterine infection, and oligohydramnios: risk factors for placental abruption. Obstet Gynecol 104(1):71–77

    Article  PubMed  Google Scholar 

  • Asrat T, Lewis DF, Garite TJ, Major CA, Nageotte MP, Towers CV, Montgomery DM, Dorchester WA (1991) Rate of recurrence of preterm premature rupture of membranes in consecutive pregnancies. Am J Obstet Gynecol 165(4 Pt 1):1111–1115

    Article  CAS  PubMed  Google Scholar 

  • AWMF LL 015–025 (2020) Prävention und Therapie der Frühgeburt. https://www.awmf.org/uploads/tx_szleitlinien/015-025l_S2k_Praevention-Therapie_Fruehgeburt_2020-02.pdf. Zugegriffen am 13.07.2022

  • Beydoun SN, Yasin SY (1986) Premature rupture of the membranes before 28 weeks: conservative management. Am J Obstet Gynecol 155(3):471–479

    Article  CAS  PubMed  Google Scholar 

  • BirkedalHansen H (1995) Proteolytic remodeling of extracellular matrix. Curr Opin Cell Biol 7(5):728–735

    Article  CAS  Google Scholar 

  • Blanco JD, Gibbs RS, Malherbe H, StricklandCholmley M, St Clair PJ, Castaneda YS (1983) A controlled study of genital mycoplasmas in amniotic fluid from patients with intra-amniotic infection. J Infect Dis 147(4):650–653

    Article  CAS  PubMed  Google Scholar 

  • Blott M, Greenough A (1988) Neonatal outcome after prolonged rupture of the membranes starting in the second trimester. Arch Dis Child 63(10):1146–1150

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Bond DM, Middleton P, Levett KM, van der Ham DP, Crowther CA, Buchanan SL, Morris J (2017) Planned early birth versus expectant management for women with preterm prelabour rupture of membranes prior to 37 weeks’ gestation for improving pregnancy outcome. Cochrane Database Syst Rev 2017(3):CD004735

    PubMed Central  Google Scholar 

  • Borgida AF, Mills AA, Feldman DM, Rodis JF, Egan JF (2000) Outcome of pregnancies complicated by ruptured membranes after genetic amniocentesis. Am J Obstet Gynecol 183(4):937–939

    Article  CAS  PubMed  Google Scholar 

  • Carroll SG, Papaioannou S, Nicolaides KH (1995) Doppler studies of the placental and fetal circulation in pregnancies with preterm prelabor amniorrhexis. Ultrasound Obstet Gynecol 5(3):184–188

    Article  CAS  PubMed  Google Scholar 

  • Chatzakis C, Papatheodorou S, Sarafidis K, Dinas K, Makrydimas G, Sotiriadis A (2020) Effect on perinatal outcome of prophylactic antibiotics in preterm prelabor rupture of membranes: network meta-analysis of randomized controlled trials. Ultrasound Obstet Gynecol 55(1):20–31

    Article  CAS  PubMed  Google Scholar 

  • Committee-Opinion (2017) Committee Opinion No. 713: antenatal corticosteroid therapy for fetal maturation. Obstet Gynecol 130(2):e102–e109

    Article  Google Scholar 

  • Crowley AE, Grivell RM, Dodd JM (2016) Sealing procedures for preterm prelabour rupture of membranes. Cochrane Database Syst Rev 2016(7):CD010218

    PubMed Central  Google Scholar 

  • Devaud YR, Züger S, Zimmermann R, Ehrbar M, Ochsenbein-Kölble N (2019) Minimally invasive surgical device for precise application of bioadhesives to prevent iPPROM. Fetal Diagn Ther 45(2):102–110

    Article  PubMed  Google Scholar 

  • Devlieger R, Millar LK, BryantGreenwood G, Lewi L, Deprest JA (2006) Fetal membrane healing after spontaneous and iatrogenic membrane rupture: a review of current evidence. Am J Obstet Gynecol 195(6):1512–1520

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dudley J, Malcolm G, Ellwood D (1991) Amniocentesis in the management of preterm premature rupture of the membranes. Aust N Z J Obstet Gynaecol 31(4):331–336

    Article  CAS  PubMed  Google Scholar 

  • Edwards SE, Grobman WA, Lappen JR, Winter C, Fox R, Lenguerrand E, Draycott T (2015) Modified obstetric early warning scoring systems (MOEWS): validating the diagnostic performance for severe sepsis in women with chorioamnionitis. Am J Obstet Gynecol 212(4):536.e538

    Article  Google Scholar 

  • Embryotox (2020) Embryotox. www.embryotox.de. Zugegriffen am 06.04.2020

  • Garite TJ, Freeman RK (1982) Chorioamnionitis in the preterm gestation. Obstet Gynecol 59(5):539–545

    CAS  PubMed  Google Scholar 

  • GBA (2021) Richtlinie des Gemeinsamen Bundesausschusses über Maßnahmen zur Qualitätssicherung der Versorgung von Früh- und Reifgeborenen gemäß § 136 Absatz 1 Nummer 2 SGB V in Verbindung mit § 92 Abs. 1 Satz 2 Nr. 13 SGB V. https://www.g-ba.de/downloads/62-492-2537/QFR-RL_2021-04-01_iK-2021-04-01.pdf. Zugegriffen am 20.07.2021

  • Gibbs RS, Blanco JD, St Clair PJ, Castaneda YS (1982) Quantitative bacteriology of amniotic fluid from women with clinical intraamniotic infection at term. J Infect Dis 145(1):1–8

    Article  CAS  PubMed  Google Scholar 

  • Gibbs RS, Blanco JD, St. Clair PJ, Castaneda YS (1983) Mycoplasma hominis and intrauterine infection in late pregnancy. Sex Transm Dis 10(4 Suppl):303–306

    CAS  PubMed  Google Scholar 

  • Gibbs RS, Blanco JD, Lipscomb K, St Clair PJ (1985) Asymptomatic parturient women with high-virulence bacteria in the amniotic fluid. Am J Obstet Gynecol 152(6 Pt 1):650–654

    Article  CAS  PubMed  Google Scholar 

  • Gilstrap LC, Cox SM (1989) Acute chorioamnionitis. Obstet Gynecol Clin N Am 16(2):373–379

    Article  Google Scholar 

  • Gomez R, Romero R, Ghezzi F, Yoon BH, Mazor M, Berry SM (1998) The fetal inflammatory response syndrome. Am J Obstet Gynecol 179(1):194–202

    Article  CAS  PubMed  Google Scholar 

  • Ham DP van der, van der Heyden JL, Opmeer BC, Mulder AL, Moonen RM, van Beek JH, Franssen MT, Bloemenkamp KW, Sikkema JM, de Groot CJ, Porath M, Kwee A, Woiski MD, Duvekot JH, Akerboom BM, van Loon AJ, de Leeuw JW, Willekes C, Mol BW, Nijhuis JG (2012a) Management of late-preterm premature rupture of membranes: the PPROMEXIL-2 trial. Am J Obstet Gynecol 207(4):276.e271–210

    Google Scholar 

  • Ham DP van der, Vijgen SM, Nijhuis JG, van Beek JJ, Opmeer BC, Mulder AL, Moonen R, Groenewout M, van Pampus MG, Mantel GD, Bloemenkamp KW, van Wijngaarden WJ, Sikkema M, Haak MC, Pernet PJ, Porath M, Molkenboer JF, Kuppens S, Kwee A, Kars ME, Woiski M, Weinans MJ, Wildschut HI, Akerboom BM, Mol BW, Willekes C, PPROMEXIL trial group (2012b) Induction of labor versus expectant management in women with preterm prelabor rupture of membranes between 34 and 37 weeks: a randomized controlled trial. PLoS Med 9(4):e1001208

    Google Scholar 

  • Hauth JC, Gilstrap LC, Hankins GDV, Connor KD (1985) Term maternal and neonatal complications of acute chorioamnionitis. Obstet Gynecol 66(1):59–62

    CAS  PubMed  Google Scholar 

  • Heyden JL van der (2014) Preterm prelabor rupture of membranes: different gestational ages, different problems, Thesis 2014

    Google Scholar 

  • Hibbard JU, Wilkins I, Sun L, Gregory K, Haberman S, Hoffman M, Kominiarek MA, Reddy U, Bailit J, Branch DW, Burkman R, Gonzalez Quintero VH, Hatjis CG, Landy H, Ramirez M, VanVeldhuisen P, Troendle J, Zhang J (2010) Respiratory morbidity in late preterm births. JAMA 304(4):419–425

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Higgins RD, Saade G, Polin RA, Grobman WA, Buhimschi IA, Watterberg K, Silver RM, Raju TN, Participants CW (2016) Evaluation and management of women and newborns with a maternal diagnosis of chorioamnionitis: summary of a workshop. Obstet Gynecol 127(3):426–436

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Hofer N, Kothari R, Morris N, Muller W, Resch B (2013) The fetal inflammatory response syndrome is a risk factor for morbidity in preterm neonates. Am J Obstet Gynecol 209(6):542.e511

    Article  Google Scholar 

  • Hofmeyr GJ, Eke AC, Lawrie TA (2014) Amnioinfusion for third trimester preterm premature rupture of membranes. Cochrane Database Syst Rev (3):Cd000942

    Google Scholar 

  • Kacerovsky M, Musilova I, Hornychova H, Kutova R, Pliskova L, Kostal M, Jacobsson B (2014) Bedside assessment of amniotic fluid interleukin-6 in preterm prelabor rupture of membranes. Am J Obstet Gynecol 211(4):385.e389

    Article  Google Scholar 

  • Kenyon S, Boulvain M, Neilson JP (2010) Antibiotics for preterm rupture of membranes. Cochrane Database Syst Rev (8):Cd001058

    Google Scholar 

  • Kenyon S, Boulvain M, Neilson JP (2013) Antibiotics for preterm rupture of membranes. Cochrane Database Syst Rev (12):Cd001058

    Google Scholar 

  • Kumar D, Moore RM, Mercer BM, Mansour JM, Redline RW, Moore JJ (2016) The physiology of fetal membrane weakening and rupture: insights gained from the determination of physical properties revisited. Placenta 42:59–73

    Article  CAS  PubMed  Google Scholar 

  • Kunze M, Klar M, Morfeld CA, Thorns B, Schild RL, Markfeld-Erol F, Rasenack R, Proempeler H, Hentschel R, Schaefer WR (2016) Cytokines in noninvasively obtained amniotic fluid as predictors of fetal inflammatory response syndrome. Am J Obstet Gynecol 215(1):96.e98

    Article  Google Scholar 

  • Leo MV, Skurnick JH, Ganesh VV, Adhate A, Apuzzio JJ (1992) Clinical chorioamnionitis is not predicted by umbilical artery Doppler velocimetry in patients with premature rupture of membranes. Obstet Gynecol 79(6):916–918

    CAS  PubMed  Google Scholar 

  • Lewis DF, Adair CD, Weeks JW, Barrilleaux PS, Edwards MS, Garite TJ (1999) A randomized clinical trial of daily nonstress testing versus biophysical profile in the management of preterm premature rupture of membranes. Am J Obstet Gynecol 181(6):1495–1499

    Article  CAS  PubMed  Google Scholar 

  • Lewis DF, Robichaux AG, Jaekle RK, Salas A, Canzoneri BJ, Horton K, Jaekle L, Stedman C (2007) Expectant management of preterm premature rupture of membranes and nonvertex presentation: what are the risks? Am J Obstet Gynecol 196(6):6

    Article  Google Scholar 

  • Mackeen AD, Seibel-Seamon J, Muhammad J, Baxter JK, Berghella V (2014) Tocolytics for preterm premature rupture of membranes. Cochrane Database Syst Rev (2):Cd007062

    Google Scholar 

  • Maged AM, Kamel HH, Sanad AS, Mahram AE, AbdAllah AA, Elkhateeb R, Bhaa HA, Hussein EA, Essam A, Ibrahim S (2021) The value of amniopatch in pregnancies associated with spontaneous preterm premature rupture of fetal membranes: a randomized controlled trial. J Matern Fetal Neonatal Med 34(2):267–273

    Article  CAS  PubMed  Google Scholar 

  • Major CA, de Veciana M, Lewis DF, Morgan MA (1995) Preterm premature rupture of membranes and abruptio placentae: is there an association between these pregnancy complications? Am J Obstet Gynecol 172(2 Pt 1):672–676

    Article  CAS  PubMed  Google Scholar 

  • Mark SP, Croughan-Minihane MS, Kilpatrick SJ (2000) Chorioamnionitis and uterine function. Obstet Gynecol 95(6 Pt 1):909–912

    PubMed  Google Scholar 

  • Melamed N, Hadar E, Ben-Haroush A, Kaplan B, Yogev Y (2009) Factors affecting the duration of the latency period in preterm premature rupture of membranes. J Matern Fetal Neonatal Med 22(11):1051–1056

    Article  PubMed  Google Scholar 

  • Mercer BM (2005) Preterm premature rupture of the membranes: current approaches to evaluation and management. Obstet Gynecol Clin N Am 32(3):411–428

    Article  Google Scholar 

  • Mercer BM, Miodovnik M, Thurnau GR, Goldenberg RL, Das AF, Ramsey RD, Rabello YA, Meis PJ, Moawad AH, Iams JD, van Dorsten JP, Paul RH, Bottoms SF, Merenstein G, Thom EA, Roberts JM, McNellis D (1997) Antibiotic therapy for reduction of infant morbidity after preterm premature rupture of the membranes. A randomized controlled trial. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. JAMA 278(12):989–995

    Article  CAS  PubMed  Google Scholar 

  • Mercer BM, Goldenberg RL, Moawad AH, Meis PJ, Iams JD, Das AF, Caritis SN, Miodovnik M, Menard MK, Thurnau GR, Dombrowski MP, Roberts JM, McNellis D (1999) The preterm prediction study: effect of gestational age and cause of preterm birth on subsequent obstetric outcome. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Am J Obstet Gynecol 181(5 Pt 1):1216–1221

    Article  CAS  PubMed  Google Scholar 

  • Mercer BM, Rabello YA, Thurnau GR, Miodovnik M, Goldenberg RL, Das AF, Meis PJ, Moawad AH, Iams JD, van Dorsten JP, Dombrowski MP, Roberts JM, McNellis D, Network N-M (2006) The NICHD-MFMU antibiotic treatment of preterm PROM study: impact of initial amniotic fluid volume on pregnancy outcome. Am J Obstet Gynecol 194(2):438–445

    Article  PubMed  Google Scholar 

  • Morris JM, Roberts CL, Bowen JR, Patterson JA, Bond DM, Algert CS, Thornton JG, Crowther CA (2016) Immediate delivery compared with expectant management after preterm pre-labour rupture of the membranes close to term (PPROMT trial): a randomised controlled trial. Lancet 387(10017):444–452

    Article  PubMed  Google Scholar 

  • Munson LA, Graham A, Koos BJ, Valenzuela GJ (1985) Is there a need for digital examination in patients with spontaneous rupture of the membranes? Am J Obstet Gynecol 153(5):562–563

    Article  CAS  PubMed  Google Scholar 

  • Musilova I, Bestvina T, Hudeckova M, Michalec I, Cobo T, Jacobsson B, Kacerovsky M (2016) Vaginal fluid interleukin-6 concentrations as a point-of-care test is of value in women with preterm prelabor rupture of membranes. Am J Obstet Gynecol 215(5):619.e612

    Article  Google Scholar 

  • Musilova I, Kacerovsky M, Stepan M, Bestvina T, Pliskova L, Zednikova B, Jacobsson B (2017) Maternal serum C-reactive protein concentration and intra-amniotic inflammation in women with preterm prelabor rupture of membranes. PLoS ONE 12(8):e0182731

    Article  PubMed  PubMed Central  Google Scholar 

  • Newton ER, Schroeder BC, Knape KG, Bennett BL (1995) Epidural analgesia and uterine function. Obstet Gynecol 85(5 Pt 1):749–755

    Article  CAS  PubMed  Google Scholar 

  • Obstetric-Care-Consensus (2017) Obstetric Care Consensus no. 6 summary: periviable birth. Obstet Gynecol 130(4):926–928

    Article  Google Scholar 

  • Palacio M, Kuhnert M, Berger R, Larios CL, Marcellin L (2014) Meta-analysis of studies on biochemical marker tests for the diagnosis of premature rupture of membranes: comparison of performance indexes. BMC Pregnancy Childbirth 14:183

    Article  PubMed  PubMed Central  Google Scholar 

  • Pappas A, Kendrick DE, Shankaran S, Stoll BJ, Bell EF, Laptook AR, Walsh MC, Das A, Hale EC, Newman NS, Higgins RD (2014) Chorioamnionitis and early childhood outcomes among extremely low-gestational-age neonates. JAMA Pediatr 168(2):137–147

    Article  PubMed  PubMed Central  Google Scholar 

  • Parry S, Strauss JF 3rd (1998) Premature rupture of the fetal membranes. N Engl J Med 338(10):663–670

    Article  CAS  PubMed  Google Scholar 

  • Pergialiotis V, Bellos I, Fanaki M, Antsaklis A, Loutradis D, Daskalakis G (2020) The impact of residual oligohydramnios following preterm premature rupture of membranes on adverse pregnancy outcomes: a meta-analysis. Am J Obstet Gynecol 222(6):628–630

    Google Scholar 

  • Quist-Nelson J, Parker P, Mokhtari N, Di Sarno R, Saccone G, Berghella V (2018a) Progestogens in singleton gestations with preterm prelabor rupture of membranes: a systematic review and metaanalysis of randomized controlled trials. Am J Obstet Gynecol 219(4):346–355.e342

    Article  CAS  PubMed  Google Scholar 

  • Quist-Nelson J, de Ruigh AA, Seidler AL, van der Ham DP, Willekes C, Berghella V, Pajkrt E, Patterson J, Espinoza D, Morris J, Mol B, Askie L, Preterm Premature Rupture of Membranes Meta-analysis (PPROMM) Collaboration (2018b) Immediate delivery compared with expectant management in late preterm prelabor rupture of membranes: an individual participant data meta-analysis. Obstet Gynecol 131(2):269–279

    Article  PubMed  Google Scholar 

  • Raju TN (2013) Moderately preterm, late preterm and early term infants: research needs. Clin Perinatol 40(4):791–797

    Article  PubMed  Google Scholar 

  • Ramsauer B, Vidaeff AC, Hosli I, Park JS, Strauss A, Khodjaeva Z, de la Cruz AA, Martinez-Astorquiza T, Horovitz J, Coatleven F, Helmer H (2013) The diagnosis of rupture of fetal membranes (ROM): a meta-analysis. J Perinat Med 41(3):233–240

    Article  CAS  PubMed  Google Scholar 

  • Rotschild A, Ling EW, Puterman ML, Farquharson D (1990) Neonatal outcome after prolonged preterm rupture of the membranes. Am J Obstet Gynecol 162(1):46–52

    Article  CAS  PubMed  Google Scholar 

  • Rouse DJ, Landon M, Leveno KJ, Leindecker S, Varner MW, Caritis SN, O’Sullivan MJ, Wapner RJ, Meis PJ, Miodovnik M, Sorokin Y, Moawad AH, Mabie W, Conway D, Gabbe SG, Spong CY, National Institute of Child Health and Human Development, Maternal-Fetal Medicine Units Network (2004) The Maternal-Fetal Medicine Units cesarean registry: chorioamnionitis at term and its duration-relationship to outcomes. Am J Obstet Gynecol 191(1):211–216

    Article  PubMed  Google Scholar 

  • Satin AJ, Maberry MC, Leveno KJ, Sherman ML, Kline DM (1992) Chorioamnionitis: a harbinger of dystocia. Obstet Gynecol 79(6):913–915

    CAS  PubMed  Google Scholar 

  • Schmitz T, Sentilhes L, Lorthe E, Gallot D, Madar H, Doret-Dion M, Beucher G, Charlier C, Cazanave C, Delorme P, Garabédian C, Azria E, Tessier V, Sénat MV, Kayem G (2019) Preterm premature rupture of the membranes: guidelines for clinical practice from the French College of Gynaecologists and Obstetricians (CNGOF). Eur J Obstet Gynecol Reprod Biol 236:1–6

    Article  PubMed  Google Scholar 

  • Shinjo A, Otsuki K, Sawada M, Ota H, Tokunaka M, Oba T, Matsuoka R, Okai T (2012) Retrospective cohort study: a comparison of two different management strategies in patients with preterm premature rupture of membranes. Arch Gynecol Obstet 286(2):337–345

    Article  PubMed  Google Scholar 

  • Silver RK, Gibbs RS, Castillo M (1986) Effect of amniotic fluid bacteria on the course of labor in nulliparous women at term. Obstet Gynecol 68(5):587–592

    CAS  PubMed  Google Scholar 

  • Simhan HN, Canavan TP (2005) Preterm premature rupture of membranes: diagnosis, evaluation and management strategies. BJOG 112(Suppl 1):32–37

    Article  PubMed  Google Scholar 

  • Soraisham AS, Singhal N, McMillan DD, Sauve RS, Lee SK, Network CN (2009) A multicenter study on the clinical outcome of chorioamnionitis in preterm infants. Am J Obstet Gynecol 200(4):372.e376

    Article  Google Scholar 

  • Tajik P, van der Ham DP, Zafarmand MH, Hof MH, Morris J, Franssen MT, de Groot CJ, Duvekot JJ, Oudijk MA, Willekes C, Bloemenkamp KW, Porath M, Woiski M, Akerboom BM, Sikkema JM, Nij Bijvank B, Mulder AL, Bossuyt PM, Mol BW (2014) Using vaginal Group B Streptococcus colonisation in women with preterm premature rupture of membranes to guide the decision for immediate delivery: a secondary analysis of the PPROMEXIL trials. BJOG 121(10):1263–1272; discussion 1273

    Article  CAS  PubMed  Google Scholar 

  • Teeffelen AS van, van der Ham DP, Oei SG, Porath MM, Willekes C, Mol BW (2010) The accuracy of clinical parameters in the prediction of perinatal pulmonary hypoplasia secondary to midtrimester prelabour rupture of fetal membranes: a meta-analysis. Eur J Obstet Gynecol Reprod Biol 148(1):3–12

    Google Scholar 

  • Teeffelen AS van, Van Der Heijden J, Oei SG, Porath MM, Willekes C, Opmeer B, Mol BW (2012) Accuracy of imaging parameters in the prediction of lethal pulmonary hypoplasia secondary to mid-trimester prelabor rupture of fetal membranes: a systematic review and meta-analysis. Ultrasound Obstet Gynecol 39(5):495–499

    Google Scholar 

  • Thomson AJ (2019) Care of women presenting with suspected preterm prelabour rupture of membranes from 24(+0) weeks of gestation: green-top guideline no. 73. BJOG 126(9):e152–e166

    Article  CAS  PubMed  Google Scholar 

  • Tita AT, Andrews WW (2010) Diagnosis and management of clinical chorioamnionitis. Clin Perinatol 37(2):339–354

    Article  PubMed  PubMed Central  Google Scholar 

  • Vintzileos AM, Campbell WA, Nochimson DJ, Weinbaum PJ (1987) Preterm premature rupture of the membranes: a risk factor for the development of abruptio placentae. Am J Obstet Gynecol 156(5):1235–1238

    Article  CAS  PubMed  Google Scholar 

  • Waters TP, Mercer BM (2009) The management of preterm premature rupture of the membranes near the limit of fetal viability. Am J Obstet Gynecol 201(3):230–240

    Article  PubMed  Google Scholar 

  • Wolf MF, Sgayer I, Miron D, Krencel A, Sheffer VF, Idriss SS, Sammour RN, Peleg D, Shachar IB, Rechnitzer H, Bornstein J (2020) A novel extended prophylactic antibiotic regimen in preterm pre-labor rupture of membranes: a randomized trial. Int J Infect Dis 96:254–259

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Frauenklinik, Marienhaus klinikum, Neuwied, Deutschland

    Richard Berger

  2. Universitätsklinik für Frauenheilkunde, Klinische Abteilung für Geburtshilfe und feto-maternale Medizin, Universitätsklinikum AKH Wien, Wien, Österreich

    Herbert Kiss

  3. Abt. Frauenheilkunde und Geburtshilfe, Klinikum Wels-Grieskirchen, Wels, Österreich

    Klaus Reisenberger

Authors
  1. Richard Berger
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Herbert Kiss
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Klaus Reisenberger
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Richard Berger .

Editor information

Editors and Affiliations

  1. Frauenklinik, Medizinische Hochschule Hannover, Hannover, Niedersachsen, Deutschland

    Constantin von Kaisenberg

  2. Klinische Abteilung für Geburtshilfe, Medizinische Universität Graz, Graz, Steiermark, Österreich

    Philipp Klaritsch

  3. Geburtshilfe, Universitätsspital Basel, Basel Universitätsspital, Basel Stadt, Schweiz

    Irene Hösli-Krais

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Berger, R., Kiss, H., Reisenberger, K. (2022). Der frühe vorzeitige Blasensprung. In: von Kaisenberg, C., Klaritsch, P., Hösli-Krais, I. (eds) Die Geburtshilfe. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44369-9_16-3

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-44369-9_16-3

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-44369-9

  • Online ISBN: 978-3-662-44369-9

  • eBook Packages: Springer Referenz Medizin

Publish with us

Policies and ethics

Chapter history

  1. Latest

    Der frühe vorzeitige Blasensprung
    Published:
    25 September 2022

    DOI: https://doi.org/10.1007/978-3-662-44369-9_16-3

  2. Der frühe vorzeitige Blasensprung
    Published:
    12 August 2022

    DOI: https://doi.org/10.1007/978-3-662-44369-9_16-2

  3. Original

    Früher vorzeitiger Blasensprung
    Published:
    11 March 2015

    DOI: https://doi.org/10.1007/978-3-662-44369-9_16-1

Search

Navigation