Pharmacopsychiatry 2008; 41(4): 158-159
DOI: 10.1055/s-2008-1062700
Letter

© Georg Thieme Verlag KG Stuttgart · New York

Successful Treatment of Long-lasting Psychosis in a Case of 22q11.2 Deletion Syndrome

U. J. Müller 1 , 2 , A. Fellgiebel 1
  • 1Department of Psychiatry, University of Mainz, Mainz, Germany
  • 2Division of Psychiatry Research and Psychogeriatric Medicine, University of Zurich, Psychiatric University Hospital, Zürich, Switzerland
Further Information

Publication History

received 06.10.2007 revised 14.01.2008

accepted 16.01.2008

Publication Date:
23 July 2008 (online)

Introduction

The 22q11. 2 deletion syndrome (22 DS) is frequently associated with psychiatric symptoms, especially psychosis. Here we report the case of a 41-year-old woman with 22 DS and a history of undiagnosed paranoid psychotic syndrome for many years that responded well to antipsychotic therapy with quetiapine.

References

  • 1 Arinami T. Analyses of the associations between the genes of 22q11 deletion syndrome and schizophrenia.  J Hum Genet. 2006;  51 1037-1045
  • 2 Domula M, Schulze D, Felber W, Gallinat J, Lang UE. Cat eye syndrome associated with schizophrenia.  Pharmacopsychiatry. 2007;  40 38-39
  • 3 Leyhe T, Haarmeier T, Dufke A, Giedke H. Mikrodeletion 22q11.2.  Nervenarzt. 2002;  73 452-457
  • 4 Maier W, Zobel A, Rietschel M. Genetics of schizophrenia and affective disorders.  Pharmacopsychiatry. 2003;  36 ((Suppl 3)) 195-202
  • 5 Murphy KC, Jones LA, Owen MJ. High rates of schizophrenia in adults with velo-cardio-facial syndrome.  Arch Gen Psychiatry. 1999;  56 940-945

Correspondence

U. J. Müller

Division of Psychiatry Research and Psychogeriatric Medicine

University of Zurich

Psychiatric University Hospital

Lenggstrasse 31

Postfach 1931

8032 Zürich

Switzerland

Email: ulf.mueller@bli.uzh.ch

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