Semin Respir Crit Care Med 2002; 23(3): 267-274
DOI: 10.1055/s-2002-33035
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Respiratory Complications of Poliomyelitis and Multiple Sclerosis

Ian J. Morales, Peter C. Gay
  • Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota
Further Information

Publication History

Publication Date:
02 August 2002 (online)

ABSTRACT

Years after suffering from poliomyelitis and completely recuperating from any of its acute complications, patients can develop postpolio syndrome (PPS), thought to be caused by progressive neuronal loss. The symptoms and manifestations of PPS vary in intensity and distribution, but many patients have respiratory involvement and will require a pulmonary evaluation for new or increased dyspnea, fatigue, or symptoms suggestive of sleep-related disordered breathing. The diagnosis, evaluation, and management of this complex problem are discussed in the first part of this article. In the second part, pulmonary complications of multiple sclerosis are described. This common neurological disease affects young adults and often requires evaluation by a pulmonologist. This review centers on the acute respiratory manifestations of multiple sclerosis and also describes the chronic effects.

REFERENCES

  • 1 Linderholm H, Werneman H. On respiratory regulation in poliomyelitis convalescents.  Acta Med Scand Suppl . 1956;  316 135-157
  • 2 Mulder D W, Rosenbaum R A, Layton Jr D D. Late progression of poliomyelitis or forme fruste amyotrophic lateral sclerosis?.  Mayo Clin Proc . 1972;  47 756-761
  • 3 Cashman N R, Maselli R, Wollmann R L. Late denervation in patients with antecedent paralytic poliomyelitis.  N Engl J Med . 1987;  317 7-12
  • 4 McComas A J, Quartly C, Griggs R C. Early and late losses of motor units after poliomyelitis.  Brain . 1997;  120 1415-1421
  • 5 Halstead L S, Rossi C D. New problems in old polio patients: results of a survey of 539 polio survivors.  Orthopedics . 1985;  8 845-850
  • 6 Windebank A J, Litchy W J, Daube J R. Late effects of paralytic poliomyelitis in Olmsted County, Minnesota.  Neurology . 1991;  41 501-507
  • 7 Ramlow J, Alexander M, LaPorte R. Epidemiology of the postpolio syndrome.  Am J Epidemiol . 1992;  136 769-786
  • 8 Ivanyi B, Nollet F, Redekop W K. Late onset polio sequelae: disabilities and handicaps in a population-based cohort of the 1956 poliomyelitis outbreak in the Netherlands.  Arch Phys Med Rehabil . 1999;  80 687-690
  • 9 Jubelt B, Agre J C. Characteristics and management of postpolio syndrome.  JAMA . 2000;  284 412-414
  • 10 Klingman J, Chui H, Corgiat M, Perry J. Functional recovery: a major risk factor for the development of postpoliomyelitis muscular atrophy.  Arch Neurol . 1988;  45 645-647
  • 11 Dean E, Ross J, Road J D. Pulmonary function in individuals with a history of poliomyelitis.  Chest . 1991;  100 118-123
  • 12 Halstead L S. Assessment and differential diagnosis for the postpolio syndrome.  Orthopedics . 1991;  14 1209-1217
  • 13 Blomstrand A, Bake B. Postpolio lung function.  Scand J Rehabil Med . 1992;  24 43-49
  • 14 Lin M C, Liaw M Y, Chen W J. Pulmonary function and spinal characteristics: their relationships in persons with idiopathic and postpoliomyelitic scoliosis.  Arch Phys Med Rehabil . 2001;  82 335-341
  • 15 Fischer D A. Poliomyelitis: late respiratory complications and management.  Orthopedics . 1985;  8 891-894
  • 16 Bach J R, Alba A S, Bohatiuk G. Mouth intermittent positive pressure ventilation in the management of postpolio respiratory insufficiency.  Chest . 1987;  91 859-864
  • 17 Midgren B. Lung function and clinical outcome in postpolio patients: a prospective cohort study during 11 years.  Eur Respir J . 1997;  10 146-149
  • 18 Borg K, Kaijser L. Lung function in patients with prior poliomyelitis.  Clin Physiol . 1990;  10 201-212
  • 19 Howard R S, Wiles C M, Spencer G T. The late sequelae of poliomyelitis.  Q J Med . 1988;  66 219-232
  • 20 Bach J R, Alba A S. Pulmonary dysfunction and sleep-disordered breathing as postpolio sequelae: evaluation and management.  Orthopedics . 1991;  14 1329-1337
  • 21 Hsu A A, Staats B A. ``Postpolio'' sequelae and sleep-related disordered breathing.  Mayo Clin Proc . 1998;  73 216-224
  • 22 Sawicka E H, Branthwaite M A. Respiration during sleep in kyphoscoliosis.  Thorax . 1987;  42 801-808
  • 23 Knobil K, Becker F S, Harper P. Dyspnea in a patient years after severe poliomyelitis. The role of cardiopulmonary exercise testing.  Chest . 1994;  105 777-781
  • 24 Elliott M W, Simonds A K. Nocturnal assisted ventilation using bilevel positive airway pressure: the effect of expiratory positive airway pressure.  Eur Respir J . 1995;  8 436-440
  • 25 Bach J R, Alba A S. Intermittent abdominal pressure ventilator in a regimen of noninvasive ventilatory support.  Chest . 1991;  99 630-636
  • 26 Baydur A, Layne E, Aral H. Long-term noninvasive ventilation in the community for patients with musculoskeletal disorders: 46-year experience and review.  Thorax . 2000;  55 4-11
  • 27 Simonds A K, Elliot M W. Outcome of domiciliary nasal intermittent positive pressure ventilation in restrictive and obstructive disorders.  Thorax . 1995;  50 604-609
  • 28 Kang S, Bach J R. Maximum insufflation capacity.  Chest . 2000;  118 61-65
  • 29 Bach J R, Rajaraman R, Ballanger F. Neuromuscular ventilatory insufficiency: effect of home mechanical ventilator use v oxygen therapy on pneumonia and hospitalization rates.  Am J Phys Med Rehabil . 1998;  77 8-19
  • 30 Ernstoff B, Wetterqvist H, Kvist H, Grimby G. Endurance training effects on individuals with postpoliomyelitis.  Arch Phys Med Rehabil . 1996;  77 843-848
  • 31 Agre J C, Rodriguez A A, Franke T M. Strength, endurance, and work capacity after muscle strengthening exercise in postpolio subjects.  Arch Phys Med Rehabil . 1997;  78 681-686
  • 32 Agre J C, Rodriguez A A. Muscular function in late polio and the role of exercise in postpolio patients.  NeuroRehabilitation . 1997;  8 107-118
  • 33 Kriz J L, Jones D R, Speier J L. Cardiorespiratory responses to upper extremity aerobic training by postpolio subjects.  Arch Phys Med Rehabil . 1992;  73 49-54
  • 34 Stanghelle J K, Festvåg L V. Postpolio syndrome: a 5-year followup.  Spinal Cord . 1997;  35 503-508
  • 35 Hauser S L, Goodkin D E. Multiple sclerosis and other demyelinating diseases. In: Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL, eds. Harrison's Principles of Internal Medicine 15th ed. New York, NY: McGraw-Hill; 2001: 2452-2461
  • 36 Victor M, Ropper A H. Principles of Neurology. 7th ed. New York, NY: McGraw-Hill; 2001
  • 37 Anderson D W, Ellenberg J H, Leventhal C M. Revised estimate of the prevalence of multiple slerosis in the United States.  Ann Neurol . 1992;  31 333-336
  • 38 Hopkins R S, Indian R W, Pinnow E, Conomy J. Multiple sclerosis in Galion, Ohio: prevalence and results of a case-control study.  Neuroepidemiology . 1991;  10 192-199
  • 39 Compston A, Ebers G, Lassmann H. McAlpine's Multiple Sclerosis.  3rd ed. London: Churchill Livingston; 1998
  • 40 Carter J L, Noseworthy J H. Ventilatory dysfunction in multiple sclerosis patients.  Clin Chest Med . 1994;  15 693-703
  • 41 Rizvi S S, Ishikawa S, Faling L J. Defect in automatic respiration in a case of multiple sclerosis.  Am J Med . 1974;  56 433-436
  • 42 Newsom-Davis J. Autonomous breathing: report of a case.  Arch Neurol . 1974;  30 480
  • 43 Mochizuki A, Yamanouchi H, Murata M. Medullary lesion revealed by MRI in a case of MS with respiratory arrest.  Neuroradiology . 1988;  30 574-576
  • 44 Cooper C B, Trend P St J, Wiles C M. Severe diaphragm weakness in multiple sclerosis.  Thorax . 1985;  40 633-634
  • 45 Kuwahira I, Kondo T, Ohta Y, Yamabayashi H. Acute respiratory failure in multiple sclerosis.  Chest . 1990;  97 246-248
  • 46 Howard R S, Wiles C M, Hirsch N P. Respiratory involvement in multiple sclerosis.  Brain . 1992;  115 479-494
  • 47 Simon R P, Gean-Marton A D, Sander J E. Medullary lesion inducing pulmonary edema: a magnetic resonance imaging study.  Ann Neurol . 1991;  30 727-730
  • 48 Poser C M, Paty D W, Scheinberg L. New diagnostic criteria for multiple sclerosis: guidelines for research protocols.  Ann Neurol . 1983;  13 227-231
  • 49 Smeltzer S C, Skurnick J H, Troiano R. Respiratory function in multiple sclerosis: utility of clinical assessment of respiratory muscle function.  Chest . 1992;  101 479-484
  • 50 Buyse B, Demedts M, Meekers J. Respiratory dysfunction in multiple sclerosis: a prospective analysis of 60 patients.  Eur Respir J . 1997;  10 139-145
  • 51 Foglio K, Clini E, Facchetti D. Respiratory muscle function and exercise capacity in multiple sclerosis.  Eur Respir J . 1994;  7 23-28
  • 52 Anonymous. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis, I: Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. The IFNB Multiple Sclerosis Study Group [see comments].  Neurology . 1993;  43 655-666
    >