CC BY 4.0 · TH Open 2021; 05(02): e195-e199
DOI: 10.1055/s-0041-1728791
Case Report

Myocardial Infarction with Nonobstructive Coronary Arteries: A Diagnostic Challenge

1   National Cardiothoracic Centre, Korle Bu Teaching Hospital, Korle Bu, Accra, Ghana
› Author Affiliations

Abstract

Myocardial infarction with nonobstructive coronary arteries (MINOCA) is a significant cause of cardiovascular morbidity, especially among non-white women younger than 55 years. It is a working diagnosis that warrants further investigation due to its varied underlying pathophysiologic mechanisms. Investigations may be hampered by unavailability of testing modalities, cost, and the expertise to carry out the tests, as they are highly specialized. Clinical history is therefore important, especially in developing countries, to predict potential causes and institute empirical treatment without the luxury of tests. Some physicians are also unaware of this phenomenon and may dismiss symptoms as functional when a coronary angiogram shows nonobstructed coronary arteries, potentially resulting in patients suffering symptoms for longer and incurring extra cost. Most importantly, it leaves them at risk of major adverse cardiovascular events. This article presents a patient with atrial fibrillation who was diagnosed with MINOCA and highlights the diagnostic challenges in evaluating MINOCA.



Publication History

Received: 06 December 2020

Accepted: 01 February 2021

Article published online:
16 June 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Marpuri R, Joung S, Gadh A. et al. Case report: assessment and management of myocardial infarction and non-obstructive coronary arteries (MINOCA): the role of microvascular coronary vasospasm. Cardiovasc Diagn Ther 2019; 9 (04) 400-405
  • 2 Gue YX, Kanji R, Gati S, Gorog DA. MI with non-obstructive coronary artery presenting with STEMI: a review of incidence, aetiology, assessment and treatment. Eur Cardiol 2020; 15: e20
  • 3 Gasior P, Desperak A, Gierlotka M. et al. Clinical characteristics, treatments, and outcomes of patients with myocardial infarction with non-obstructive coronary arteries (MINOCA): results from a multicenter national registry. J Clin Med 2020; 9 (09) 2779
  • 4 Vranken NPA, Pustjens TFS, Kolkman E. et al. MINOCA: the caveat of absence of coronary obstruction in myocardial infarction. Int J Cardiol Heart Vasc 2020; 29: 100572
  • 5 Pasupathy S, Tavella R, McRae S, Beltrame JF. Myocardial infarction with non-obstructive coronary arteries - diagnosis and management. Eur Cardiol 2015; 10 (02) 79-82
  • 6 Abdu FA, Mohammed AQ, Liu L, Xu Y, Che W. Myocardial infarction with nonobstructive coronary arteries (MINOCA): a review of the current position. Cardiology 2020; 145 (09) 543-552
  • 7 Vidal-Perez R, Abou Jokh Casas C, Agra-Bermejo RM. et al. Myocardial infarction with non-obstructive coronary arteries: a comprehensive review and future research directions. World J Cardiol 2019; 11 (12) 305-315
  • 8 Pasupathy S, Tavella R, Beltrame JF. The what, when, who, why, how and where of myocardial infarction with non-obstructive coronary arteries (MINOCA). Circ J 2016; 80 (01) 11-16
  • 9 Pacheco Claudio C, Quesada O, Pepine CJ, Noel Bairey Merz C. Why names matter for women: MINOCA/INOCA (myocardial infarction/ischemia and no obstructive coronary artery disease). Clin Cardiol 2018; 41 (02) 185-193
  • 10 Ruddox V, Sandven I, Munkhaugen J, Skattebu J, Edvardsen T, Otterstad JE. Atrial fibrillation and the risk for myocardial infarction, all-cause mortality and heart failure: a systematic review and meta-analysis. Eur J Prev Cardiol 2017; 24 (14) 1555-1566
  • 11 Baumgartner H, Falk V, Bax JJ. et al. ESC/EACTS Guidelines for the management of valvular heart disease. Eur Heart J 2017; 38 (36) 2739-2791
  • 12 Collet JP, Thiele H, Barbato E. et al. ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 2020; ehaa575 Available at: https://doi.org/10.1093/eurheartj/ehaa575