Am J Perinatol 2011; 28(3): 195-200
DOI: 10.1055/s-0030-1266156
© Thieme Medical Publishers

Mode of Delivery and Outcomes in Very Low-Birth-Weight Infants in the Vertex Presentation

Danielle E. Durie1 , Anthony C. Sciscione2 , Matthew K. Hoffman2 , Amy B. Mackley3 , David A. Paul3
  • 1Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York
  • 2Department of Obstetrics and Gynecology, Section of Neonatology, Christiana Care Health System, Newark, Delaware
  • 3Department of Pediatrics, Section of Neonatology, Christiana Care Health System, Newark, Delaware
Further Information

Publication History

Publication Date:
03 September 2010 (online)

ABSTRACT

We sought to determine the relationship between mode of delivery and neonatal outcomes in infants <1500 g in a vertex presentation. This was a retrospective cohort study of singleton, vertex-presenting infants weighing <1500 g in a level III neonatal intensive care unit between July 1993 and July 2006. Infants were divided into vaginal or cesarean delivery, and outcomes were compared with univariable and multivariable analysis. Of the 937 infants that met inclusion criteria, 402 (42.9%) underwent cesarean delivery. After controlling for potential confounding variables, there was no increased odds of death (odds ratio [OR] = 1.6: 95% confidence interval [CI] 0.8 to 3.0), severe intraventricular hemorrhage (IVH; OR = 1.2: 95% CI 0.7 to 1.2), necrotizing enterocolitis (OR = 0.82: 95% CI 0.35 to 1.9), or sepsis (OR = 0.79: 95% CI 0.44 to 13) in the vaginally delivered group compared with the cesarean group. In a post hoc analysis, this study had 80% power to detect an absolute difference in death or severe IVH of 6% between study groups, with an α of 0.05. In our population of very low-birth-weight infants, there was no association between mode of delivery and neonatal outcomes.

REFERENCES

  • 1 Gravenhorst J B, Schrueder A, Veen S et al.. Breech delivery in very preterm and very low birthweight infants in The Netherlands.  BJOG. 1993;  100 411-415
  • 2 Jain L, Ferre C, Vidyasagar D. Cesarean delivery of the breech very-low-birth-weight infant: does it make a difference?.  J Matern Fetal Med. 1998;  7 28-31
  • 3 Suidan J S, Sayegh R A. Delivery of the low birthweight and the very low birthweight breech: cesarean section or vaginal delivery?.  J Perinat Med. 1989;  17 145-149
  • 4 Görbe E, Chasen S, Harmath A, Patkós P, Papp Z. Very-low-birthweight breech infants: short-term outcome by method of delivery.  J Matern Fetal Med. 1997;  6 155-158
  • 5 Jonas H A, Lumley J M. The effect of mode of delivery on neonatal mortality in very low birthweight infants born in Victoria, Australia: caesarean section is associated with increased survival in breech-presenting, but not vertex-presenting, infants.  Paediatr Perinat Epidemiol. 1997;  11 181-199
  • 6 Bottoms S F, Paul R H, Iams J D National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units et al. Obstetric determinants of neonatal survival: influence of willingness to perform cesarean delivery on survival of extremely low-birth-weight infants.  Am J Obstet Gynecol. 1997;  176 960-966
  • 7 Deulofeut R, Sola A, Lee B, Buchter S, Rahman M, Rogido M. The impact of vaginal delivery in premature infants weighing less than 1,251 grams.  Obstet Gynecol. 2005;  105 525-531
  • 8 Ment L R, Oh W, Ehrenkranz R A, Philip A GS, Duncan C C, Makuch R W. Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infants.  Am J Obstet Gynecol. 1995;  172 795-800
  • 9 Meirowitz N B, Ananth C V, Smulian J C, Vintzileos A M. Effect of labor on infant morbidity and mortality with preterm premature rupture of membranes: United States population-based study.  Obstet Gynecol. 2001;  97 494-498
  • 10 Paul D A, Sciscione A, Leef K H, Stefano J L. Caesarean delivery and outcome in very low birthweight infants.  Aust N Z J Obstet Gynaecol. 2002;  42 41-45
  • 11 Kitchen W, Ford G W, Doyle L W et al.. Cesarean section or vaginal delivery at 24 to 28 weeks' gestation: comparison of survival and neonatal and two-year morbidity.  Obstet Gynecol. 1985;  66 149-157
  • 12 Malloy M H, Onstad L, Wright E. National Institute of Child Health and Human Development Neonatal Research Network . The effect of cesarean delivery on birth outcome in very low birth weight infants.  Obstet Gynecol. 1991;  77 498-503
  • 13 Kato E H, Yamada H, Matsumoto Y, Hattori S, Makinoda S, Fujimoto S. Relation between perinatal factors and outcome of very low birth weight infants.  J Perinat Med. 1996;  24 677-686
  • 14 Riskin A, Riskin-Mashiah S, Lusky A, Reichman B. Israel Neonatal Network . The relationship between delivery mode and mortality in very low birthweight singleton vertex-presenting infants.  BJOG. 2004;  111 1365-1371
  • 15 Wylie B J, Davidson L L, Batra M, Reed S D. Method of delivery and neonatal outcome in very low-birthweight vertex-presenting fetuses.  Am J Obstet Gynecol. 2008;  198 640 e1-e7 discussion e1-e4
  • 16 Anderson G D, Bada H S, Sibai B M et al.. The relationship between labor and route of delivery in the preterm infant.  Am J Obstet Gynecol. 1988;  158 (6 Pt 1) 1382-1390
  • 17 Anderson G D, Bada H S, Shaver D C et al.. The effect of cesarean section on intraventricular hemorrhage in the preterm infant.  Am J Obstet Gynecol. 1992;  166 1091-1099 discussion 1099-1101
  • 18 Wadhawan R, Vohr B R, Fanaroff A A et al.. Does labor influence neonatal and neurodevelopmental outcomes of extremely-low-birth-weight infants who are born by cesarean delivery?.  Am J Obstet Gynecol. 2003;  189 501-506
  • 19 Lee H C, Gould J B. Survival rates and mode of delivery for vertex preterm infants according to small- or appropriate-for-gestational-age status.  Pediatrics. 2006;  118 1836-1844
  • 20 Grant A, Glazener C M. Elective cesarean delivery versus expectant management for delivery of the small baby.  Cochrane Database Syst Rev. 2007;  4
  • 21 Costakos D T, Love L A, Kirby R S. The computerized perinatal database: are the data reliable?.  Am J Perinatol. 1998;  15 453-459
  • 22 Papile L A, Burstein J, Burstein R, Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm.  J Pediatr. 1978;  92 529-534
  • 23 Walsh M C, Kliegman R M. Necrotizing enterocolitis: treatment based on staging criteria.  Pediatr Clin North Am. 1986;  33 179-201
  • 24 Ballard J L, Khoury J C, Wedig K, Wang L, Eilers-Walsman B L, Lipp R. New Ballard Score, expanded to include extremely premature infants.  J Pediatr. 1991;  119 417-423
  • 25 Lubchenco L O, Hansman C, Boyd E. Intrauterine growth in length and head circumference as estimated from live births at gestational ages from 26 to 42 weeks.  Pediatrics. 1966;  37 403-408
  • 26 ACOG Committee on Obstetric Practice . ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002, American College of Obstetricians and Gynecologists.  Int J Gynaecol Obstet. 2002;  77 67-75
  • 27 Fanaroff A A, Stoll B J, Wright L L NICHD Neonatal Research Network et al. Trends in neonatal morbidity and mortality for very low birthweight infants.  Am J Obstet Gynecol. 2007;  196 147 e1-e8
  • 28 Lee H C, Gould J B. Survival advantage associated with cesarean delivery in very low birth weight vertex neonates.  Obstet Gynecol. 2006;  107 97-105
  • 29 Kirby R S. Invited commentary: using vital statistics databases for perinatal epidemiology: does the quality go in before the name goes on?.  Am J Epidemiol. 2001;  154 889-890
  • 30 Lydon-Rochelle M T, Holt V L, Cárdenas V et al.. The reporting of pre-existing maternal medical conditions and complications of pregnancy on birth certificates and in hospital discharge data.  Am J Obstet Gynecol. 2005;  193 125-134
  • 31 Adams M. Validity of birth certificate data for the outcome of the previous pregnancy, Georgia, 1980–1995.  Am J Epidemiol. 2001;  154 883-888

Danielle DurieM.D. M.P.H. 

Department of Obstetrics and Gynecology, University of Rochester Medical Center

601 Elmwood Avenue, Box 668, Rochester, NY 14642

Email: danielledurie@gmail.com

    >