Rectal Meckel’s diverticulum

 

 Permissions and Reprints

A 39-year-old woman presented for colon cancer screening colonoscopy. She had no abdominal complaints. The entire colonoscopy was normal, except that the standard retroflexed view in the rectum demonstrated a 2-cm diverticulum without raised margins 5 cm from the anal verge ([Fig. 1 a, b]).

Fig. 1 a, b Retroflexed endoscopic views of the rectal Meckel’s diverticulum.

Endoscopically the mucosa appeared fairly edematous, but without malignant characteristics. The histological examination of the biopsies obtained revealed rectal mucosa abutting ectopic gastric mucosa without Helicobacter pylori ([Fig. 2]).

Fig. 2 Histological section shows rectal mucosa abutting ectopic gastric mucosa (hematoxylin and eosin staining, × 100).

The technetium Tc 99 m pertechnetate scan was negative. Follow-up sigmoidoscopy performed 3 months later showed an unchanged diverticulum. Again, histological examination demonstrated ectopic gastric mucosa. As the patient remained asymptomatic, to date no surgical resection or further endoscopic screening has been performed.

Heterotopic gastric mucosa can be observed anywhere along the human gastrointestinal tract. It is rarely seen in the rectum: only about 30 cases have been reported since the first description in 1939 [1]. In the clinical setting, gastric heterotopia typically presents as either an ulcerative lesion or abnormal mucosa in the rectum [2]. The origin of gastric mucosa in the rectum is believed to be failure of developmental descent of the embryonic hindgut. The occurrence of gastric heterotopia within a hindgut developmental anomaly such as rectal duplication is exceptional [3]. In clinical practice, a so-called rectal Meckel’s diverticulum may present with acute profuse rectal bleeding, especially in children and young adults [4]. In these cases surgical resection is advised. In patients with peptic ulceration, treatment with H₂-blockers or proton pump inhibitors should be prescribed first. A rectal Meckel’s diverticulum may also be asymptomatic, as it was in our patient. We choose not to perform preventive resection or regular endoscopic screening, so long as the course is uneventful.

Endoscopy_UCTN_Code_CCL_1AD_2AJ

References

• 1 Ewell G H, Jackson R H. Aberrant gastric mucosa in the rectum with ulceration and hemorrhage.  World J Surg. 1939;  38 641-643
  PubMedGoogle Scholar
• 2 Garmendia M, Aparicio J R, Martínez J. et al . Heterotopic gastric mucosa in the rectum.  Gastrointest Endosc. 2007;  65 921
  CrossrefPubMedGoogle Scholar
• 3 Stockman J M, Young V T, Jenkins A L. Duplication of the rectum containing gastric mucosa.  JAMA. 1960;  173 1223-1225
  PubMedGoogle Scholar
• 4 Forshaw J F, Dhia D, Cole S. et al . Rectal Meckel’s diverticulum: an unusual cause of rectal bleeding.  Int J Colorectal Dis. 2006;  21 485-487
  CrossrefPubMedGoogle Scholar

Nanne K. H. de BoerMD, PhD 

Department of Gastroenterology and Hepatology
Kennemer Gasthuis

PO Box 417
2000 AK
Haarlem
The Netherlands

Email: KHN.deBoer@vumc.nl