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Pharmacopsychiatry 2009; 42(2): 79-81
DOI: 10.1055/s-0028-1103290
Letter

© Georg Thieme Verlag KG Stuttgart · New York

Cardiac Left Bundle Branch Block and Pancytopenia in Anorexia Nervosa: Higher Risk with Mirtazapine and Pantoprazole? Case Report

A. Walder 1 , P. Baumann 2
  • 1Sanatorium Kilchberg Psychiatrische Privatklinik, Kilchberg, Switzerland
  • 2Département de Psychiatrie, Centre Hospitalier Universitaire Vaudois (DP-CHUV), Prilly-Lausanne, Switzerland
Further Information

Publication History

received 11.06.2008

accepted 06.10.2008

Publication Date:
23 March 2009 (online)

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A 36-year-old female patient suffering from anorexia nervosa of the restricting type, depression, symptoms of gastro-esophageal reflux and several cardiac abnormalities including left branch block was treated with mirtazapine and pantoprazole. Several hematological abnormalities appeared, i.e., a pancytopenia including a severe leukopenia (neutropenia), erythrocytopenia and a thrombocytopenia, which almost resumed upon discontinuation of medication. This situation of low nutrition represents probably an important risk factor for the development of severe hematological disturbances and cardiac alterations, including left branch block and it complicates pharmacotherapeutic interventions.

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Correspondence

Dr. A. Walder

Sanatorium Kilchberg Psychiatrische Privatklinik

Alte Landstraße 70-84

8802 Kilchberg

Switzerland

Phone: +41/44/716 42 62

Fax: +41/44/716 43 43

Email: a.walder@sanatorium-kilchberg.ch

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