Ayurveda bei onkologischen Erkrankungen

 

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Summary

In der Onkologie kann Ayurveda eine komplementärmedizinische Rolle spielen. Ayurveda betrachtet den Körper als selbstregulierendes Milieu, gesteuert durch funktionelle Prinzipien (v. a. Dosha, Agni) und physiologische Strukturen (v. a. Dhatu, Mala, Srotas). Krebserkrankungen werden im Ayurveda als Systemerkrankungen verstanden. So sind in die Ätiopathogenese onkologischer Erkrankungen zumeist alle 3 Dosha involviert.

Die supportive Ayurveda-Behandlung von Krebs kann je nach vorliegender Fragestellung Ursachenvermeidung oder Prävention, spezielle körperliche Reinigungsverfahren (Pancakarma), Stoffwechselkorrekturmaßnahmen, Immunmodulation, Geweberegeneration (Rasayana) sowie psychomentale Stärkung durch Meditation, therapeutisches Yoga und Manualtherapie umfassen. Die Grenzen der komplementäronkologischen Ayurveda-Behandlung in Deutschland liegen vor allem in der Verfügbarkeit seriöser Versorgungsangebote und -sicherer Phytotherapeutika sowie in dem finanziellen Aufwand, da Krankenversicherungsträger die Kosten dieser Therapien in der Regel nicht übernehmen. Wissenschaftliche Evidenz entsprechend EbM ist noch sehr limitiert, jedoch existiert ein breites, über mehrere Jahrtausende systematisiertes, erfahrungsmedizinisches Wissen. In der Praxis zeigt sich, dass Ayurveda eine sinnvolle Ergänzung zur konventionellen Krebsbehandlung sein kann, vor allem wenn es darum geht, die onkospezifische Lebensqualität zu verbessern und Nebenwirkungen zu verringern.

Publication History

Article published online:
16 May 2024

© 2024. Thieme. All rights reserved.

© Karl F. Haug Verlag in MVS Medizinverlage Stuttgart GmbH & Co.
KG

• Literatur

• 1 Kessler C, Michalsen A. The role of whole medical systems in global medicine. Forsch Komplementmed 2012; 19 (02) 65-66 DOI: 10.1159/000338294.
  CrossrefPubMedGoogle Scholar
• 2 Ranade S. Ayurveda: Wesen und Methodik; 16 Tabellen. Stuttgart: Thieme; 2004
  Google Scholar
• 3 Lad V. Lehrbuch des Ayurveda. Die Grundprinzipien. Kandern: Narayana; 2012
  Google Scholar
• 4 World Health Organization. WHO benchmarks for the training of ayurveda (2022). Im Internet. https://iris.who.int/bitstream/handle/10665/351480/9789240042711-eng.pdf?sequence=1 Stand: 15.04.2024
  Google Scholar
• 5 World Health Organization. WHO benchmarks for the practice of ayurveda (2022). Im Internet. https://iris.who.int/bitstream/handle/10665/351475/9789240042674-eng.pdf?sequence=1 Stand: 15.04.2024
  Google Scholar
• 6 World Health Organization. WHO global centre for traditional medicine (2020). Im Internet. https://www.who.int/initiatives/who-global-centre-for-traditional-medicine Stand: 15.04.2024
  Google Scholar
• 7 Central Council for Research on Ayurvedic Sciences. LOI between OCCAM-NCI and CCRAS-India (2020). Im Internet. https://www.energy.gov/sites/prod/files/US-India%20ST%20Agreement.pdf Stand: 15.04.2024
  Google Scholar
• 8 Government of India. National health profile (2022). Im Internet. https://cbhidghs.mohfw.gov.in/WriteReadData/l892s/94203846761680514146.pdf Stand: 15.04.2024
  Google Scholar
• 9 Keßler CH. Ayurveda, Yoga, Meditation – Traditionelle Indische Medizin und ihr Bezug zu den fünf Säulen der Naturheilkunde [Habilitationsschrift]. Berlin: Charité; 2020
  Google Scholar
• 10 Mao JJ, Pillai GG, Andrade CJ. et al Integrative oncology: Addressing the global challenges of cancer prevention and treatment. CA Cancer J Clin 2022; 72 (02) 144-164 DOI: 10.3322/caac.21706.
  CrossrefPubMedGoogle Scholar
• 11 Broom A, Nayar K, Tovey P. et al Indian cancer patients’ use of traditional, complementary and alternative medicine (TCAM) and delays in presentation to hospital. Oman Med J 2009; 24 (02) 99-102 DOI: 10.5001/omj.2009.24.
  CrossrefPubMedGoogle Scholar
• 12 Kumar D, Goel NK, Pandey AK. et al Complementary and alternative medicine use among the cancer patients in northern india. South Asian J Cancer 2016; 05 (01) 8-11 DOI: 10.4103/2278-330X.179689.
  Article in Thieme ConnectPubMedGoogle Scholar
• 13 Shetty N, Rai PR, Shetty A. Study of the use of traditional, complementary, and alternative medicine in Indian cancer patients. IJMPO 2019; 40 (03) 365-368 DOI: 10.4103/ijmpo.ijmpo_200_17.
  Article in Thieme ConnectGoogle Scholar
• 14 Lim EJ, Vardy JL, Oh BS. A scoping review on models of integrative medicine: What is known from the existing literature?. J Altern Complement Med 2017; 23 (01) 8-17 DOI: 10.1089/acm.2016.0263.
  CrossrefPubMedGoogle Scholar
• 15 Deshmukh V, Kulkarni A, Bhargava S. et al Effectiveness of combinations of ayurvedic drugs in alleviating drug toxicity and improving quality of life of cancer patients treated with chemotherapy. Support Care Cancer 2014; 22 (11) 3007-3015 DOI: 10.1007/s00520-014-2294-0.
  CrossrefPubMedGoogle Scholar
• 16 Palliyaguru DL, Singh SV, Kensler TW. Withania somnifera: From prevention to treatment of cancer. Mol Nutr Food Res 2016; 60 (06) 1342-1353 DOI: 10.1002/mnfr.201500756.
  CrossrefPubMedGoogle Scholar
• 17 Giordano A, Tommonaro G. Curcumin and cancer. Nutrients 2019; 11 (10) 2376 DOI: 10.3390/nu11102376.
  CrossrefPubMedGoogle Scholar
• 18 Gundeti MS, Dedge A, Dave P. Ayurveda and plant-based interventions for cancer management: A systematic review. J Drug Res Ayurvedic Sci 2017; 02 (02) 64-80 DOI: 10.5005/JP-JOURNALS-10059-0009.
  CrossrefGoogle Scholar
• 19 Tomeh MA, Hadianamrei R, Zhao X. A review of curcumin and its derivatives as anticancer agents. Int J Mol Sci 2019; 20 (05) 1033 DOI: 10.3390/ijms20051033.
  CrossrefPubMedGoogle Scholar
• 20 Ryan Wolf J, Heckler CE, Guido JJ. et al Oral curcumin for radiation dermatitis: A URCC NCORP study of 686 breast cancer patients. Support Care Cancer 2018; 26 (05) 1543-1552 DOI: 10.1007/s00520-017-3957-4.
  CrossrefPubMedGoogle Scholar
• 21 Hejazi J, Rastmanesh R, Molana H. et al Effect of curcumin supplementation during radiotherapy on oxidative status of patients with prostate cancer: A double blinded, randomized, placebo-controlled study. Nutrition and Cancer 2016; 68 (01) 77-85 DOI: 10.1080/01635581.2016.1115527.
  CrossrefPubMedGoogle Scholar
• 22 Ide H, Tokiwa S, Sakamaki K. et al Combined inhibitory effects of soy isoflavones and curcumin on the production of prostate-specific antigen. Prostate 2010; 70 (10) 1127-1133 DOI: 10.1002/pros.21147.
  CrossrefPubMedGoogle Scholar
• 23 Saggam A, Tillu G, Dixit S. et al Withania somnifera (L.) dunal: A potential therapeutic adjuvant in cancer. J Ethnopharmaco 2020; 255: 112759 DOI: 10.1016/j.jep.2020.112759.
  CrossrefPubMedGoogle Scholar
• 24 CAM-Cancer Consortium, Kompetenznetz Komplementärmedizin in der Onkologie – KOKON. Kurkumin (05/2022). Im Internet. https://www.onkopedia.com/de/onkopedia/guidelines/kurkumin/@@guideline/html/index.html Stand: 15.04.2024
  Google Scholar
• 25 Hübner M, Keßler C. Aryurveda. In: Matthes H, Schad F, Hofheinz R-D, Hrsg. Integrative Onkologie: DIN Beratungsmanual für Ärzte und Apotheker. Stuttgart: Wissenschaftliche Verlagsgesellschaft; 2022: 76
  Google Scholar
• 26 Gupta SN, Stapelfeldt E. Ayurveda-Medizin: Kaya-cikitsa-Therapiekonzepte für innere Erkrankungen. Stuttgart: Thieme; 2023
  Google Scholar
• 27 Sharma RK, Dash VB. Caraka Samhita. Vol 1. Varanasi: Chowkhamba Sanskrit Series Office; 2018
  Google Scholar
• 28 Murthy KRS. Sushruta Samhita. Vol 1–3. Varanasi: Chaukhambha Orientalia; 2016
  Google Scholar
• 29 Murthy K. Vagbhata’s Astanga Hrdayam. Vol. 1. Varanasi: Chaukhambha Orientalia; 2001: 53-57
  Google Scholar
• 30 Sushruta An english translation of the Sushruta Samhita. Vol. 1 of 3: Sutrasthanam. London: Forgotten Books; 2018
  Google Scholar
• 31 Dhruva A, Hecht FM, Miaskowski C. et al Correlating traditional ayurvedic and modern medical perspectives on cancer: Results of a qualitative study. Altern Complement Med 2014; 20 (05) 364-370 DOI: 10.1089/acm.2013.0259.
  CrossrefPubMedGoogle Scholar
• 32 Patel D, Mansoori A. Cancer – an ayurvedic perspective. IJARPB 2012; 02 (02) 179-195
  Google Scholar
• 33 Matthes H, Schad F, Hofheinz R-D. Integrative Onkologie: Ein Beratungsmanual für Ärzte und Apotheker. Stuttgart: Wissenschaftliche Verlagsgesellschaft; 2022
  Google Scholar
• 34 Sahu R, Vinayka J. Samprapti and it's clinical importance. JETIR 2022; 09 (10) b1-b4
  Google Scholar
• 35 Chauhan A, Semwal DK, Mishra SP. et al Ayurvedic concept of shatkriyakala: A traditional knowledge of cancer pathogenesis and therapy. J Integr Med 2017; 15 (02) 88-94 DOI: 10.1016/S2095-4964(17)60311-X.
  CrossrefPubMedGoogle Scholar
• 36 Gupta HH. Stellenwert von Ayurveda und Yoga in der Onkologie. ZKM 2016; 08 (02) 31-35 DOI: 10.1055/s-0036-1582000.
  Article in Thieme ConnectGoogle Scholar
• 37 Metri K, Bhargav H, Chowdhury P. et al Ayurveda for chemo-radiotherapy induced side effects in cancer patients. J Stem Cells 2013; 08 (02) 115
  Google Scholar
• 38 Rastogi S. Ayurvedic principles of food and nutrition: Translating theory into evidence-based practice, in ayurvedic science of food and nutrition. Berlin: Springer; 2013: 3-14
  Google Scholar
• 39 Ayush MO.. Cancer (o.D.). Im Internet. https://namayush.gov.in/sites/all/themes/webcms/images/org_str/CANCER.pdf Stand: 15.04.2024
  Google Scholar
• 40 Murthy Srikantha K. Vagbhata’s astanga hrdayam – text, English translation, notes, appendix and indices. Varanasi: Chowkhamba Krishnadas Academy; 2000
  Google Scholar
• 41 Micke O, Hübner J, Münstedt K. Ayurveda. Der Onkologe 2009; 15: 792-798 DOI: 10.1007/s00761-009-1655-7.
  CrossrefGoogle Scholar
• 42 Bhandari M, Ravipati AS, Reddy N. et al Traditional ayurvedic medicines: Pathway to develop anti-cancer drugs. J Mol Pharm Org Process Res 2015; 03 (03) 130 DOI: 10.4172/2329-9053.1000130.
  CrossrefGoogle Scholar
• 43 May K, Jeitler M, Murthy V. et al A case report of acute hepatitis involving the medicinal herb tinospora cordifolia along with other variables. J Integr Complement Med 2023; 29 (05) 327-333 DOI: 10.1089/jicm.2022.0755.
  CrossrefPubMedGoogle Scholar
• 44 Kammler G. Yoga in der Komplementärmedizin bei Krebs. Im Fokus Onkologie 2022; 25 (03) 3
  CrossrefGoogle Scholar
• 45 Cramer H, Haller H. Yoga in der supportiven Onkologie: Wie ist die Evidenz?. Deutsche Zeitschrift für Onkologie 2020; 52 (04) 148-151 DOI: 10.1055/a-1276-6333.
  Article in Thieme ConnectGoogle Scholar
• 46 Mackenzie MJ, Carlson LE, Speca M. Mindfulness-based stress reduction (MBSR) in oncology: Rationale and review. JEBIM 2005; 02: 139-145 DOI: 10.2165/01197065-200502030-00005.
  CrossrefGoogle Scholar
• 47 Jain M, Mishra A, Yadav V. et al Long-term yogic intervention decreases serum interleukins IL-10 and IL-1β and improves cancer-related fatigue and functional scale during radiotherapy/chemotherapy in breast cancer patients: A randomized control study. Support Care Cancer 2022; 31 (01) 6 DOI: 10.1007/s00520-022-07487-4.
  CrossrefPubMedGoogle Scholar
• 48 Hilfiker R, Meichtry A, Eicher M. et al Exercise and other non-pharmaceutical interventions for cancer-related fatigue in patients during or after cancer treatment: A systematic review incorporating an indirect-comparisons meta-analysis. Br J Sports Med 2018; 52 (10) 651-658 DOI: 10.1136/bjsports-2016-096422.
  CrossrefPubMedGoogle Scholar
• 49 Baliga MS, Dsouza JJ. Amla (Emblica officinalis gaertn), a wonder berry in the treatment and prevention of cancer. Eur J Cancer Prev 2011; 20 (03) 225-239 DOI: 10.1097/CEJ.0b013e32834473f4.
  CrossrefPubMedGoogle Scholar
• 50 Vyas P, Thakar AB, Baghel MS. et al Efficacy of Rasayana Avaleha as adjuvant to radiotherapy and chemotherapy in reducing adverse effects. Ayu 2010; 31 (04) 417-423 DOI: 10.4103/0974-8520.82029.
  CrossrefPubMedGoogle Scholar
• 51 Bhat PM, Umale H, Lahankar M. Amalaki: A review on functional and pharmacological properties. JPP 2019; 08 (03) 4378-4382
  Google Scholar
• 52 Dutta R, Khalil R, Green R. et al Withania Somnifera (Ashvagandha) and withaferin a: Potential in integrative oncology. Int J Mol Sci 2019; 20 (21) 5310 DOI: 10.3390/ijms20215310.
  CrossrefPubMedGoogle Scholar
• 53 Dhama K, Rekha K, Swati S. et al Medicinal and beneficial health applications of Tinospora cordifolia (Guduchi): A miraculous herb countering various diseases/disorders and its immunomodulatory effects. Recent Pat Endocr Metab Immune Drug Discov 2017; 10 (02) 96-111 DOI: 10.2174/1872214811666170301105101.
  CrossrefPubMedGoogle Scholar
• 54 Beriwal VK, Singh B, Thapliyal S. et al A clinical evaluation of Guduchi (Tinospora cordifolia) and Yashtimadhu (Glycyrrhiza glabra) as chemopreventive agent in cancer treatment. ASJO 2019; 05 (02) 064-071 DOI: 10.1055/s-0039-3401639.
  Article in Thieme ConnectGoogle Scholar
• 55 Yadav V, Krishnan A, Vohora D. A systematic review on Piper longum L.: Bridging traditional knowledge and pharmacological evidence for future translational research. J Ethnopharmacol 2020; 30 (247) 112255 DOI: 10.1016/j.jep.2019.112255.
  CrossrefPubMedGoogle Scholar
• 56 Macit MS, Koyuncu S, Kocaadam-Bozkurt B. et al Evaluation of ginger (Zingiber officinale roscoe) on energy metabolism and obesity: Systematic review and meta-analysis. Food Rev Int 2019; 35 (07) 685-706 DOI: 10.1080/87559129.2019.1608556.
  CrossrefGoogle Scholar
• 57 Peterson CT Rodionov DA, Iablokov SN. et al Prebiotic potential of culinary spices used to support digestion and bioabsorption. Evid Based Complement Alternat Med 2019; 2019: 8973704 DOI: 10.1155/2019/8973704.
  CrossrefPubMedGoogle Scholar
• 58 Sreenivasan S, Krishnakumar S. Synergistic effect of curcumin in combination with anticancer agents in human retinoblastoma cancer cell lines. Curr Eye Res 2015; 40 (11) 1153-1165 DOI: 10.3109/02713683.2014.987870.
  CrossrefPubMedGoogle Scholar
• 59 Bandey I, Chiou SH, Huang AP. et al Progranulin promotes temozolomide resistance of glioblastoma by orchestrating DNA repair and tumor stemness. Oncogene 2015; 34 (14) 1853-1864 DOI: 10.1038/onc.2014.92.
  CrossrefPubMedGoogle Scholar
• 60 Naidoo DB, Chuturgoon AA, Phulukdaree A. et al Centella asiatica modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC's). BMC Complement Altern Med 2017; 17 (01) 377 DOI: 10.1186/s12906-017-1865-2.
  CrossrefPubMedGoogle Scholar
• 61 Kumari I, Kaurav H, Choudhary G.. Rubia cordifolia (Manjishtha): A review based upon its ayurvedic and medicinal uses. HJHS 2021; 06 (02) 17-28 DOI: 10.22270/hjhs.v6i2.96.
  CrossrefGoogle Scholar
• 62 Khundrakpam A, Sivakami PS. Phytonutrient rich medicinal plant “Centella asiatica” as brain enhancing potential – A review. IJSR 2016; 05 (03) 1984-1987
  Google Scholar
• 63 Mishra S, Aeri V, Gaur PK. et al Phytochemical, therapeutic, and ethnopharmacological overview for a traditionally important herb: Boerhavia diffusa linn. Biomed Res Int 2014; 2014: 808302 DOI: 10.1155/2014/808302.
  CrossrefPubMedGoogle Scholar
• 64 Palatty PL, Azmidah A, Rao S. et al Topical application of a sandal wood oil and turmeric based cream prevents radiodermatitis in head and neck cancer patients undergoing external beam radiotherapy: A pilot study. Br J Radiol 2014; 87 1038 20130490 DOI: 10.1259/bjr.20130490.
  CrossrefPubMedGoogle Scholar
• 65 Prasad S, Srivastava SK. Oxidative stress and cancer: Chemopreventive and therapeutic role of triphala. Antioxidants (Basel) 2020; 09 (01) 72 DOI: 10.3390/antiox9010072.
  CrossrefPubMedGoogle Scholar
• 66 Baliga MS. Triphala, ayurvedic formulation for treating and preventing cancer: A review. J Altern Complement Med 2010; 16 (12) 1301-1308 DOI: 10.1089/acm.2009.0633.
  CrossrefPubMedGoogle Scholar