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Treatment of osteopenia
Reviews in Endocrine and Metabolic Disorders Open Access 28 June 2011
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References
Mashiba T et al. (2005) The effects of suppressed bone remodeling by bisphosphonates on microdamage accumulation and degree of mineralization in the cortical bone of dog rib. J Bone Miner Metab 23 (Suppl): 36–42
Komatsubara S et al. (2004) Suppressed bone turnover by long-term bisphosphonate treatment accumulates microdamage but maintains intrinsic material properties in cortical bone of dog rib. J Bone Miner Res 19: 999–1005
Komatsubara S et al. (2003) Long-term treatment of incadronate disodium accumulates microdamage but improves the trabecular bone microarchitecture in dog vertebra. J Bone Miner Res 18: 512–520
Burr DB et al. (2003) Tissue mineralization is increased following 1-year treatment with high doses of bisphosphonates in dogs. Bone 33: 960–969
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The synopsis was written by Vicky Heath, Associate Editor, Nature Clinical Practice.
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The author has received research support and consultation fees from the following companies: Amgen, Bayer, Chugai, Eli Lilly, GlaxoSmithKline, Gry-Pharma, Merck Sharpe & Dohme, Novartis, Nycomed, Organon, OttoBock, Pfizer, Procter & Gamble, Roche, Schering, Servier, Symarc, Teva, and Wyeth.
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Felsenberg, D. Osteonecrosis of the jaw—a potential adverse effect of bisphosphonate treatment. Nat Rev Endocrinol 2, 662–663 (2006). https://doi.org/10.1038/ncpendmet0348
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DOI: https://doi.org/10.1038/ncpendmet0348
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