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Spinal Cord Stimulation in Cluster Headache

  • Trigeminal Autonomic Cephalalgias (M Matharu, Section Editor)
  • Published:
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Abstract

Neurostimulation techniques for the treatment of primary headache syndromes, particularly for chronic cluster headache (CCH), have received much interest in the recent years. Occipital nerve stimulation (ONS) has yielded favourable clinical results, and is becoming a routine treatment for refractory chronic cluster headache in specialized centres. Meanwhile, other promising techniques, such as spinal cord stimulation (SCS) or sphenopalatine ganglion stimulation, are emerging. This article reviews the current state of clinical research for neurostimulation techniques for chronic cluster headache, and particularly the pros and cons of SCS and ONS.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Silberstein SD, Olesen J, Bousser MG, Diener HC, Dodick D, First M, et al. The International Classification of Headache Disorders, 2nd Edition (ICHD-II)—revision of criteria for 8.2 Medication-overuse headache. Cephalalgia. 2005;25(6):460–5. doi:10.1111/j.1468-2982.2005.00878.x.

    Article  PubMed  CAS  Google Scholar 

  2. Dodick DW, Capobianco DJ. Treatment and management of cluster headache. Curr Pain Headache Rep. 2001;5(1):83–91.

    Article  PubMed  CAS  Google Scholar 

  3. Ekbom K, Lindgren L, Nilsson BY, Hardebo JE, Waldenlind E. Retro-Gasserian glycerol injection in the treatment of chronic cluster headache. Cephalalgia. 1987;7(1):21–7.

    Article  PubMed  CAS  Google Scholar 

  4. Sweet WH. Surgical treatment of chronic cluster headache. Headache. 1988;28(10):669–70.

    Article  PubMed  CAS  Google Scholar 

  5. Mathew NT, Hurt W. Percutaneous radiofrequency trigeminal gangliorhizolysis in intractable cluster headache. Headache. 1988;28(5):328–31.

    Article  PubMed  CAS  Google Scholar 

  6. Donnet A, Valade D, Regis J. Gamma knife treatment for refractory cluster headache: prospective open trial. J Neurol Neurosurg Psychiatry. 2005;76(2):218–21. doi:10.1136/jnnp.2004.041202.

    Article  PubMed  CAS  Google Scholar 

  7. Donnet A, Tamura M, Valade D, Regis J. Trigeminal nerve radiosurgical treatment in intractable chronic cluster headache: unexpected high toxicity. Neurosurgery. 2006;59(6):1252–7. doi:10.1227/01.NEU.0000245612.86484.7. discussion 7.

    Article  PubMed  Google Scholar 

  8. McClelland 3rd S, Tendulkar RD, Barnett GH, Neyman G, Suh JH. Long-term results of radiosurgery for refractory cluster headache. Neurosurgery. 2006;59(6):1258–62. doi:10.1227/01.NEU.0000245614.94108.4B. discussion 62–3.

    PubMed  Google Scholar 

  9. McClelland 3rd S, Barnett GH, Neyman G, Suh JH. Repeat trigeminal nerve radiosurgery for refractory cluster headache fails to provide long-term pain relief. Headache. 2007;47(2):298–300. doi:10.1111/j.1526-4610.2006.00701.x.

    Article  PubMed  Google Scholar 

  10. Green MW. Long-term follow-up of chronic cluster headache treated surgically with trigeminal tractotomy. Headache. 2003;43(5):479–81.

    Article  PubMed  Google Scholar 

  11. Kirkpatrick PJ, O’Brien MD, MacCabe JJ. Trigeminal nerve section for chronic migrainous neuralgia. Br J Neurosurg. 1993;7(5):483–90.

    Article  PubMed  CAS  Google Scholar 

  12. Jarrar RG, Black DF, Dodick DW, Davis DH. Outcome of trigeminal nerve section in the treatment of chronic cluster headache. Neurology. 2003;60(8):1360–2.

    Article  PubMed  CAS  Google Scholar 

  13. Rowed DW. Chronic cluster headache managed by nervus intermedius section. Headache. 1990;30(7):401–6.

    Article  PubMed  CAS  Google Scholar 

  14. Morgenlander JC, Wilkins RH. Surgical treatment of cluster headache. J Neurosurg. 1990;72(6):866–71. doi:10.3171/jns.1990.72.6.0866.

    Article  PubMed  CAS  Google Scholar 

  15. Solomon S, Apfelbaum RI. Surgical decompression of the facial nerve in the treatment of chronic cluster headache. Arch Neurol. 1986;43(5):479–82.

    Article  PubMed  CAS  Google Scholar 

  16. Felisati G, Arnone F, Lozza P, Leone M, Curone M, Bussone G. Sphenopalatine endoscopic ganglion block: a revision of a traditional technique for cluster headache. Laryngoscope. 2006;116(8):1447–50. doi:10.1097/01.mlg.0000227997.48020.44.

    Article  PubMed  Google Scholar 

  17. • Sanders M, Zuurmond WW. Efficacy of sphenopalatine ganglion blockade in 66 patients suffering from cluster headache: a 12- to 70-month follow-up evaluation. J Neurosurg. 1997;87(6):876–80. doi:10.3171/jns.1997.87.6.0876. A large study on radiofrequency treatment in episodic and in chronic CH.

    Article  PubMed  CAS  Google Scholar 

  18. Lad SP, Lipani JD, Gibbs IC, Chang SD, Adler Jr JR, Henderson JM. Cyberknife targeting the pterygopalatine ganglion for the treatment of chronic cluster headaches. Neurosurgery. 2007;60(3):E580–1. doi:10.1227/01.NEU.0000255348.33582.DE. discussioin E1.

    Article  PubMed  Google Scholar 

  19. • Goadsby PJ, Schoenen J, Ferrari MD, Silberstein SD, Dodick D. Towards a definition of intractable headache for use in clinical practice and trials. Cephalalgia. 2006;26(9):1168–70. doi:10.1111/j.1468-2982.2006.01173.x. The widely accepted definition of intractable headache to which in most clinical trials is referred to.

    Article  PubMed  CAS  Google Scholar 

  20. •• May A, Bahra A, Buchel C, Frackowiak RS, Goadsby PJ. Hypothalamic activation in cluster headache attacks. Lancet. 1998;352(9124):275–8. doi:10.1016/S0140-6736(98)02470-2. The first report of hypothalamic activation during CH attacks, an observation that later led to the advent of DBS for CCH.

    Article  PubMed  CAS  Google Scholar 

  21. Sprenger T, Boecker H, Tolle TR, Bussone G, May A, Leone M. Specific hypothalamic activation during a spontaneous cluster headache attack. Neurology. 2004;62(3):516–7.

    Article  PubMed  CAS  Google Scholar 

  22. Franzini A, Ferroli P, Leone M, Broggi G. Stimulation of the posterior hypothalamus for treatment of chronic intractable cluster headaches: first reported series. Neurosurgery. 2003;52(5):1095–9. discussion 9–101.

    Article  PubMed  Google Scholar 

  23. Leone M. Deep brain stimulation in headache. Lancet Neurol. 2006;5(10):873–7. doi:10.1016/S1474-4422(06)70575-0.

    Article  PubMed  Google Scholar 

  24. Leone M, Proietti Cecchini A, Franzini A, Broggi G, Cortelli P, Montagna P, et al. Lessons from 8 years’ experience of hypothalamic stimulation in cluster headache. Cephalalgia. 2008;28(7):787–97. doi:10.1111/j.1468-2982.2008.01627.x. discussion 98.

    Article  PubMed  CAS  Google Scholar 

  25. Schoenen J, Di Clemente L, Vandenheede M, Fumal A, De Pasqua V, Mouchamps M, et al. Hypothalamic stimulation in chronic cluster headache: a pilot study of efficacy and mode of action. Brain. 2005;128(Pt 4):940–7. doi:10.1093/brain/awh411.

    Article  PubMed  CAS  Google Scholar 

  26. Fontaine D, Lazorthes Y, Mertens P, Blond S, Geraud G, Fabre N, et al. Safety and efficacy of deep brain stimulation in refractory cluster headache: a randomized placebo-controlled double-blind trial followed by a 1-year open extension. J Headache Pain. 2010;11(1):23–31. doi:10.1007/s10194-009-0169-4.

    Article  PubMed  CAS  Google Scholar 

  27. Matharu MS, Zrinzo L. Deep brain stimulation in cluster headache: hypothalamus or midbrain tegmentum? Curr Pain Headache Rep. 2010;14(2):151–9. doi:10.1007/s11916-010-0099-5.

    Article  PubMed  Google Scholar 

  28. Matharu MS, Zrinzo L. Deep brain stimulation in cluster headache. Expert Rev Neurother. 2011;11(4):473–5. doi:10.1586/ern.11.35.

    Article  PubMed  Google Scholar 

  29. • Weiner RL, Reed KL. Peripheral Neurostimulation for Control of Intractable Occipital Neuralgia. Neuromodulation. 1999;2(3):217–21. In this study, occipital nerve stimulation was described for the first time.

    Article  PubMed  CAS  Google Scholar 

  30. Schwedt TJ, Dodick DW, Hentz J, Trentman TL, Zimmerman RS. Occipital nerve stimulation for chronic headache–long-term safety and efficacy. Cephalalgia. 2007;27(2):153–7. doi:10.1111/j.1468-2982.2007.01272.x.

    Article  PubMed  CAS  Google Scholar 

  31. Schwedt TJ, Dodick DW, Trentman TL, Zimmerman RS. Occipital nerve stimulation for chronic cluster headache and hemicrania continua: pain relief and persistence of autonomic features. Cephalalgia. 2006;26(8):1025–7. doi:10.1111/j.1468-2982.2006.01142.x.

    Article  PubMed  CAS  Google Scholar 

  32. Matharu M, Watkins L, Shanahan P. Treatment of medically intractable SUNCT and SUNA with occipital nerve stimulation. J Neurol Neurosurg Psychiatry. 2010;81:e51–e2.

    Article  Google Scholar 

  33. Burns B, Watkins L, Goadsby PJ. Treatment of medically intractable cluster headache by occipital nerve stimulation: long-term follow-up of eight patients. Lancet. 2007;369(9567):1099–106. doi:10.1016/S0140-6736(07)60328-6.

    Article  PubMed  Google Scholar 

  34. Burns B, Watkins L, Goadsby PJ. Treatment of intractable chronic cluster headache by occipital nerve stimulation in 14 patients. Neurology. 2009;72(4):341–5. doi:10.1212/01.wnl.0000341279.17344.c9.

    Article  PubMed  CAS  Google Scholar 

  35. Magis D, Allena M, Bolla M, De Pasqua V, Remacle JM, Schoenen J. Occipital nerve stimulation for drug-resistant chronic cluster headache: a prospective pilot study. Lancet Neurol. 2007;6(4):314–21. doi:10.1016/S1474-4422(07)70058-3.

    Article  PubMed  Google Scholar 

  36. Magis D, Gerardy PY, Remacle JM, Schoenen J. Sustained effectiveness of occipital nerve stimulation in drug-resistant chronic cluster headache. Headache. 2011;51(8):1191–201. doi:10.1111/j.1526-4610.2011.01973.x.

    Article  PubMed  Google Scholar 

  37. de Quintana-Schmidt C, Casajuana-Garreta E, Molet-Teixido J, Garcia-Bach M, Roig C, Clavel-Laria P, et al. Stimulation of the occipital nerve in the treatment of drug-resistant cluster headache. Rev Neurol. 2010;51(1):19–26.

    Article  PubMed  Google Scholar 

  38. Tronnier V, Rasche D. Subcutaneous peripheral stimulation of the greater occipital nerve for the treatment of chronic headache syndromes. Schmerz. 2010;24(5):441–8. doi:10.1007/s00482-010-0970-7.

    Article  PubMed  CAS  Google Scholar 

  39. Fontaine D, Christophe Sol J, Raoul S, Fabre N, Geraud G, Magne C, et al. Treatment of refractory chronic cluster headache by chronic occipital nerve stimulation. Cephalalgia. 2011;31(10):1101–5. doi:10.1177/0333102411412086.

    Article  PubMed  Google Scholar 

  40. Mueller OM, Gaul C, Katsarava Z, Diener HC, Sure U, Gasser T. Occipital nerve stimulation for the treatment of chronic cluster headache—lessons learned from 18 months experience. Cent Eur Neurosurg. 2011;72(2):84–9. doi:10.1055/s-0030-1270476.

    Article  PubMed  CAS  Google Scholar 

  41. Ibarra E. Neuromodulación del Ganglio Esfenopalatino para Aliviar los Síntomas de la Cefalea en Racimos. Reporte de un Caso. Boletín El Dolor. 2007;46(16):12–8.

    Google Scholar 

  42. • Ansarinia M, Rezai A, Tepper SJ, Steiner CP, Stump J, Stanton-Hicks M, et al. Electrical stimulation of sphenopalatine ganglion for acute treatment of cluster headaches. Headache. 2010;50(7):1164–74. doi:10.1111/j.1526-4610.2010.01661.x. This study describes electrical stimulation of the SPG, a technique for treatment of acute CH.

    Article  PubMed  Google Scholar 

  43. Tepper SJ, Rezai A, Narouze S, Steiner C, Mohajer P, Ansarinia M. Acute treatment of intractable migraine with sphenopalatine ganglion electrical stimulation. Headache. 2009;49(7):983–9. doi:10.1111/j.1526-4610.2009.01451.x.

    Article  PubMed  Google Scholar 

  44. •• Shealy CN, Mortimer JT, Reswick JB. Electrical inhibition of pain by stimulation of the dorsal columns: preliminary clinical report. Anesth Analg. 1967;46(4):489–91. The first report of dorsal column stimulation.

    Article  PubMed  CAS  Google Scholar 

  45. •• Cameron T. Safety and efficacy of spinal cord stimulation for the treatment of chronic pain: a 20-year literature review. J Neurosurg. 2004;100(3 Suppl Spine):254–67. A comprehensive and detailed review on outcome and complication rate of SCS.

    PubMed  Google Scholar 

  46. Meglio M, Cioni B, Rossi GF. Spinal cord stimulation in management of chronic pain. A 9-year experience. J Neurosurg. 1989;70(4):519–24. doi:10.3171/jns.1989.70.4.0519.

    Article  PubMed  CAS  Google Scholar 

  47. De La Porte C, Van de Kelft E. Spinal cord stimulation in failed back surgery syndrome. Pain. 1993;52(1):55–61.

    Article  Google Scholar 

  48. Hassenbusch SJ, Stanton-Hicks M, Covington EC. Spinal cord stimulation versus spinal infusion for low back and leg pain. Acta Neurochir Suppl. 1995;64:109–15.

    Article  PubMed  CAS  Google Scholar 

  49. Ohnmeiss DD, Rashbaum RF, Bogdanffy GM. Prospective outcome evaluation of spinal cord stimulation in patients with intractable leg pain. Spine (Phila Pa 1976). 1996;21(11):1344–50. discussion 51.

    Article  CAS  Google Scholar 

  50. •• Kumar K, Taylor RS, Jacques L, Eldabe S, Meglio M, Molet J, et al. Spinal cord stimulation versus conventional medical management for neuropathic pain: a multicentre randomised controlled trial in patients with failed back surgery syndrome. Pain. 2007;132(1–2):179–88. doi:10.1016/j.pain.2007.07.028. An international multicentre RCT that showed that SCS provides pain relief and improves health-related quality of life and functional capacity in patients with neuropathic pain secondary to failed back surgery syndrome.

    Article  PubMed  Google Scholar 

  51. Kemler MA, Reulen JP, Barendse GA, van Kleef M, de Vet HC, van den Wildenberg FA. Impact of spinal cord stimulation on sensory characteristics in complex regional pain syndrome type I: a randomized trial. Anesthesiology. 2001;95(1):72–80.

    Article  PubMed  CAS  Google Scholar 

  52. Harke H, Gretenkort P, Ladleif HU, Rahman S. Spinal cord stimulation in sympathetically maintained complex regional pain syndrome type I with severe disability. A prospective clinical study. Eur J Pain. 2005;9(4):363–73. doi:10.1016/j.ejpain.2004.09.003.

    Article  PubMed  Google Scholar 

  53. Kemler MA, de Vet HC, Barendse GA, van den Wildenberg FA, van Kleef M. Spinal cord stimulation for chronic reflex sympathetic dystrophy–five-year follow-up. N Engl J Med. 2006;354(22):2394–6. doi:10.1056/NEJMc055504.

    Article  PubMed  CAS  Google Scholar 

  54. Harke H, Gretenkort P, Ladleif HU, Koester P, Rahman S. Spinal cord stimulation in postherpetic neuralgia and in acute herpes zoster pain. Anesth Analg. 2002;94(3):694–700. table of contents.

    Article  PubMed  Google Scholar 

  55. •• Mannheimer C, Eliasson T, Augustinsson LE, Blomstrand C, Emanuelsson H, Larsson S, et al. Electrical stimulation versus coronary artery bypass surgery in severe angina pectoris: the ESBY study. Circulation. 1998;97(12):1157–63. The ESBY study showed that coronary arterial bypass grafting and SCS appear to be equivalent methods in terms of symptom relief in this group of patients.

    Article  PubMed  CAS  Google Scholar 

  56. Ubbink DT, Vermeulen H. Spinal cord stimulation for non-reconstructable chronic critical leg ischaemia. Cochrane Database Syst Rev. 2005;(3):CD004001. doi:10.1002/14651858.CD004001.pub2.

  57. Bennett D, Alo K, Oakley J, Feler C. Spinal Cord Stimulation for Complex Regional. Pain Syndrome I [RSD]: a Retrospective. Multicenter Experience from 1995 to 1998 of 101 Patients. Neuromodulation. 1999;2(3):202–10.

    Article  PubMed  CAS  Google Scholar 

  58. Forouzanfar T, Kemler MA, Weber WE, Kessels AG, van Kleef M. Spinal cord stimulation in complex regional pain syndrome: cervical and lumbar devices are comparably effective. Br J Anaesth. 2004;92(3):348–53. doi:10.1093/bja/aeh072.

    Article  PubMed  CAS  Google Scholar 

  59. Francaviglia N, Silvestro C, Maiello M, Bragazzi R, Bernucci C. Spinal cord stimulation for the treatment of progressive systemic sclerosis and Raynaud’s syndrome. Br J Neurosurg. 1994;8(5):567–71.

    Article  PubMed  CAS  Google Scholar 

  60. Simpson BA, Bassett G, Davies K, Herbert C, Pierri M. Cervical spinal cord stimulation for pain: a report on 41 patients. Neuromodulation. 2003;6(1):20–6. doi:10.1046/j.1525-1403.2003.03003.x.

    Article  PubMed  Google Scholar 

  61. Wolter T, Kieselbach K. Cervical spinal cord stimulation: an analysis of 23 patients with long-term follow-up. Pain Physician. 2012;15(3):203–12.

    PubMed  Google Scholar 

  62. Vallejo R, Kramer J, Benyamin R. Neuromodulation of the cervical spinal cord in the treatment of chronic intractable neck and upper extremity pain: a case series and review of the literature. Pain Physician. 2007;10(2):305–11.

    PubMed  Google Scholar 

  63. • Tomycz ND, Deibert CP, Moossy JJ. Cervicomedullary junction spinal cord stimulation for head and facial pain. Headache. 2011;51(3):418–25. doi:10.1111/j.1526-4610.2010.01829.x. This study describes long-term results of cervicomedullary junction stimulation, a technique that comes very near to hcSCS. In contrast to hcSCS, the authors used paddle electrodes that they implanted under general anesthesia via laminotomy C1.

    Article  PubMed  Google Scholar 

  64. • Wolter T, Kaube H, Mohadjer M. High cervical epidural neurostimulation for cluster headache: case report and review of the literature. Cephalalgia. 2008;28(10):1091–4. doi:10.1111/j.1468-2982.2008.01661.x. The first case report of hcSCS for CCH.

    Article  PubMed  CAS  Google Scholar 

  65. • Wolter T, Kiemen A, Kaube H. High cervical spinal cord stimulation for chronic cluster headache. Cephalalgia. 2011;31(11):1170–80. doi:10.1177/0333102411412627. The first series of hc SCS for CCH.

    Article  PubMed  Google Scholar 

  66. •• Linderoth B, Meyerson BA. Spinal cord stimulation: exploration of the physiological basis of a widely used therapy. Anesthesiology. 2010;113(6):1265–7. doi:10.1097/ALN.0b013e3181fcf590. A comprehensive and condensed article about the physiological mechanisms of action of SCS.

    Article  PubMed  Google Scholar 

  67. Yakhnitsa V, Linderoth B, Meyerson BA. Spinal cord stimulation attenuates dorsal horn neuronal hyperexcitability in a rat model of mononeuropathy. Pain. 1999;79(2–3):223–33.

    Article  PubMed  CAS  Google Scholar 

  68. Linderoth B, Stiller CO, Gunasekera L, O’Connor WT, Ungerstedt U, Brodin E. Gamma-aminobutyric acid is released in the dorsal horn by electrical spinal cord stimulation: an in vivo microdialysis study in the rat. Neurosurgery. 1994;34(3):484–8. discussion 8–9.

    Article  PubMed  CAS  Google Scholar 

  69. Stiller CO, Cui JG, O’Connor WT, Brodin E, Meyerson BA, Linderoth B. Release of gamma-aminobutyric acid in the dorsal horn and suppression of tactile allodynia by spinal cord stimulation in mononeuropathic rats. Neurosurgery. 1996;39(2):367–74. discussion 74–5.

    Article  PubMed  CAS  Google Scholar 

  70. Cui JG, Meyerson BA, Sollevi A, Linderoth B. Effect of spinal cord stimulation on tactile hypersensitivity in mononeuropathic rats is potentiated by simultaneous GABA(B) and adenosine receptor activation. Neurosci Lett. 1998;247(2–3):183–6.

    Article  PubMed  CAS  Google Scholar 

  71. Schechtmann G, Song Z, Ultenius C, Meyerson BA, Linderoth B. Cholinergic mechanisms involved in the pain relieving effect of spinal cord stimulation in a model of neuropathy. Pain. 2008;139(1):136–45. doi:10.1016/j.pain.2008.03.023.

    Article  PubMed  CAS  Google Scholar 

  72. El-Khoury C, Hawwa N, Baliki M, Atweh SF, Jabbur SJ, Saade NE. Attenuation of neuropathic pain by segmental and supraspinal activation of the dorsal column system in awake rats. Neuroscience. 2002;112(3):541–53.

    Article  PubMed  CAS  Google Scholar 

  73. Bartsch T, Goadsby PJ. Stimulation of the greater occipital nerve induces increased central excitability of dural afferent input. Brain. 2002;125(Pt 7):1496–509.

    Article  PubMed  Google Scholar 

  74. Kerr FW, Olafson RA. Trigeminal and cervical volleys. Convergence on single units in the spinal gray at C-1 and C-2. Arch Neurol. 1961;5:171–8.

    Article  PubMed  CAS  Google Scholar 

  75. Holsheimer J, Barolat G, Struijk JJ, He J. Significance of the spinal cord position in spinal cord stimulation. Acta Neurochir Suppl. 1995;64:119–24.

    Article  PubMed  CAS  Google Scholar 

  76. Holsheimer J, den Boer JA, Struijk JJ, Rozeboom AR. MR assessment of the normal position of the spinal cord in the spinal canal. AJNR Am J Neuroradiol. 1994;15(5):951–9.

    PubMed  CAS  Google Scholar 

  77. Turner JA, Loeser JD, Deyo RA, Sanders SB. Spinal cord stimulation for patients with failed back surgery syndrome or complex regional pain syndrome: a systematic review of effectiveness and complications. Pain. 2004;108(1–2):137–47. doi:10.1016/j.pain.2003.12.016.

    Article  PubMed  Google Scholar 

  78. Taylor RS, Van Buyten JP, Buchser E. Spinal cord stimulation for chronic back and leg pain and failed back surgery syndrome: a systematic review and analysis of prognostic factors. Spine (Phila Pa 1976). 2005;30(1):152–60.

    Google Scholar 

  79. Barolat G, Peacock WJ, Staudt LA. Pain and spasticity. In: EC B, editor. Spine surgery: Techniques, complication avoidance, and management. 2nd ed. Philadelphia: Elsevier Churchill Livingstone; 2005. p. 1239–52.

    Google Scholar 

  80. Meyer SC, Swartz K, Johnson JP. Quadriparesis and spinal cord stimulation: case report. Spine (Phila Pa 1976). 2007;32(19):E565–8. doi:10.1097/BRS.0b013e31814541dc.

    Article  Google Scholar 

  81. Smith CC, Lin JL, Shokat M, Dosanjh SS, Casthely D. A report of paraparesis following spinal cord stimulator trial, implantation and revision. Pain Physician. 2010;13(4):357–63.

    PubMed  Google Scholar 

  82. Rosenow JM, Stanton-Hicks M, Rezai AR, Henderson JM. Failure modes of spinal cord stimulation hardware. J Neurosurg Spine. 2006;5(3):183–90. doi:10.3171/spi.2006.5.3.183.

    Article  PubMed  Google Scholar 

  83. Brewer AC, Trentman TL, Ivancic MG, Vargas BB, Rebecca AM, Zimmerman RS, et al. Long-term outcome in occipital nerve stimulation patients with medically intractable primary headache disorders. Neuromodulation. 2012. doi:10.1111/j.1525-1403.2012.00490.x.

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Conflict of Interest

Dr. Tilman Wolter reported receiving a travel grant from Boston Scientific.

Dr. Holger Kaube reported no conflicts of interest relevant to this article.

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This article is part of the Topical Collection on Trigeminal Autonomic Cephalalgias

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Wolter, T., Kaube, H. Spinal Cord Stimulation in Cluster Headache. Curr Pain Headache Rep 17, 324 (2013). https://doi.org/10.1007/s11916-013-0324-0

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