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The Effectiveness of Single-Anastomosis Duodenoileal Bypass with Sleeve Gastrectomy/One Anastomosis Duodenal Switch (SADI-S/OADS): an Updated Systematic Review

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Abstract

Single-anastomosis duodenoileal bypass with sleeve gastrectomy/one anastomosis duodenal switch (SADI-S/OADS) was developed as a bariatric operation with reduced overall morbidity and lasting weight loss results. We performed a systematic review of the literature, including 14 studies reporting on weight loss, comorbidity resolution, postoperative complications, and nutritional deficiencies following SADI-S. Twelve months after SADI-S, the mean total body weight lost ranged from 21.5 to 41.2%, with no weight regain being observed after 24 months. The comorbidity resolution rate was 72.6% for diabetes, 77.2% for dyslipidemia, and 59.0% for hypertension cases. The need for reoperation was the most common postoperative complication. While several patients developed nutrient deficiencies, SADI-S seems to be an overall safe and effective bariatric operation.

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Authors and Affiliations

  1. Derby Royal Hospital, University Hospitals of Derby and Burton NHS Trust, Derby, UK

    Dimitrios Spinos

  2. Surgery Working Group, Society of Junior Doctors, Athens, Greece

    Dimitrios Spinos, Konstantinos Skarentzos, Stepan M. Esagian & Konstantinos P. Economopoulos

  3. Department of Medicine, School of Health Sciences, Democritus University of Thrace, Alexandroupolis, Greece

    Konstantinos Skarentzos

  4. Department of Surgery, Duke University Medical Center, 2301 Erwin Rd, Durham, NC, 27710, USA

    Keri A. Seymour & Konstantinos P. Economopoulos

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  1. Dimitrios Spinos
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Correspondence to Konstantinos P. Economopoulos.

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Spinos, D., Skarentzos, K., Esagian, S.M. et al. The Effectiveness of Single-Anastomosis Duodenoileal Bypass with Sleeve Gastrectomy/One Anastomosis Duodenal Switch (SADI-S/OADS): an Updated Systematic Review. OBES SURG 31, 1790–1800 (2021). https://doi.org/10.1007/s11695-020-05188-7

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