Abstract
Despite the notable prevalence and comorbidity of tobacco cigarette dependence and chronic pain, relatively little is known about potential mechanisms of action. Research has emphasized the utility of identifying core underlying dimensions that reflect shared etiological processes, and it has been posited that anxiety-relevant transdiagnostic factors may be particularly important to understanding pain-smoking comorbidity. This review examined the empirical literature linking pain-related fear (fear of pain and activities that elicit pain), pain-related anxiety (anxious responses to pain), and anxiety sensitivity (degree to which the experience of anxiety is expected to have deleterious consequences) to both chronic pain and tobacco cigarette smoking. We then integrated this literature to inform a conceptual model explicating the function of anxiety-relevant transdiagnostic factors in pain-tobacco smoking comorbidity. Finally, we drew upon this conceptual model to highlight novel clinical implications and inform future research.
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Ahmed, S. H., & Koob, G. F. (2005). Transition to drug addiction: A negative reinforcement model based on an allostatic decrease in reward function. Psychopharmacology (Berl), 180(3), 473–490.
Asmundson, G. J. (1999). Anxiety sensitivity and chronic pain: Empirical findings, clinical implications, and future directions. Anxiety sensitivity, 1999, 269–285.
Asmundson, G. J., & Norton, G. R. (1995). Anxiety sensitivity in patients with physically unexplained chronic back pain: A preliminary report. Behaviour Research and Therapy, 33(7), 771–777.
Asmundson, G. J., Norton, P. J., & Veloso, F. (1999). Anxiety sensitivity and fear of pain in patients with recurring headaches. Behaviour Research and Therapy, 37(8), 703–713.
Assayag, Y., Bernstein, A., Zvolensky, M. J., Steeves, D., & Stewart, S. S. (2012). Nature and role of change in anxiety sensitivity during NRT-aided cognitive-behavioral smoking cessation treatment. Cognitive Behaviour Therapy, 41(1), 51–62.
Avallone, K. M., & McLeish, A. C. (2015). Anxiety sensitivity as a mediator of the association between asthma and smoking. Journal of Asthma, 52(5), 498–504.
Bailey, K. M., Carleton, R. N., Vlaeyen, J. W., & Asmundson, G. J. (2010). Treatments addressing pain-related fear and anxiety in patients with chronic musculoskeletal pain: A preliminary review. Cognitive Behaviour Therapy, 39(1), 46–63.
Baker, T. B., Piper, M. E., McCarthy, D. E., Majeskie, M. R., & Fiore, M. C. (2004). Addiction motivation reformulated: An affective processing model of negative reinforcement. Psychological Review, 111(1), 33–51. https://doi.org/10.1037/0033-295X.111.1.33.
Bakhshaie, J., Kulesz, P. A., Garey, L., Langdon, K. J., Businelle, M. S., Leventhal, A. M., et al. (2018). A prospective investigation of the synergistic effect of change in anxiety sensitivity and dysphoria on tobacco withdrawal. Journal of Consulting and Clinical Psychology, 86(1), 69.
Bakhshaie, J., Zvolensky, M. J., Langdon, K. J., Leventhal, A. M., Smits, J. A., Allan, N., et al. (2016). Anxiety sensitivity class membership moderates the effects of pre-quit reduction in anxiety sensitivity on quit-day tobacco craving. Journal of Anxiety Disorders, 39, 79–87.
Battista, S. R., Stewart, S. H., Fulton, H. G., Steeves, D., Darredeau, C., & Gavric, D. (2008). A further investigation of the relations of anxiety sensitivity to smoking motives. Addictive Behaviors, 33(11), 1402–1408.
Bishop, K. L., Holm, J. E., Borowiak, D. M., & Wilson, B. A. (2001). Perceptions of pain in women with headache: A laboratory investigation of the influence of pain-related anxiety and fear. Headache: The Journal of Head and Face Pain, 41(5), 494–499.
Boersma, K., & Linton, S. J. (2006). Expectancy, fear and pain in the prediction of chronic pain and disability: A prospective analysis. European Journal of Pain, 10(6), 551–551.
Boogaard, S., Heymans, M. W., De Vet, H., Peters, M. L., Loer, S. A., Zuurmond, W., et al. (2015). Predictors of persistent neuropathic pain—A systematic review. Pain Physician, 18(5), 433–457.
Boswell, J. F., Farchione, T. J., Sauer-Zavala, S., Murray, H. W., Fortune, M. R., & Barlow, D. H. (2013). Anxiety sensitivity and interoceptive exposure: A transdiagnostic construct and change strategy. Behavior Therapy, 44(3), 417–431.
Broman-Fulks, J. J., Berman, M. E., Rabian, B. A., & Webster, M. J. (2004). Effects of aerobic exercise on anxiety sensitivity. Behaviour Research and Therapy, 42(2), 125–136.
Brown, R. A., Kahler, C. W., Zvolensky, M. J., Lejuez, C., & Ramsey, S. E. (2001). Anxiety sensitivity: Relationship to negative affect smoking and smoking cessation in smokers with past major depressive disorder. Addictive Behaviors, 26(6), 887–899.
Brown, R. A., Lejuez, C. W., Kahler, C. W., & Strong, D. R. (2002). Distress tolerance and duration of past smoking cessation attempts. Journal of Abnormal Psychology, 111(1), 180–185. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/11866171.
Brown, R. A., Reed, K. P., Bloom, E. L., Minami, H., Strong, D. R., Lejuez, C. W., et al. (2013). Development and preliminary randomized controlled trial of a distress tolerance treatment for smokers with a history of early lapse. Nicotine & Tobacco Research. 15, 2005–2015
Carleton, R. N., Abrams, M. P., Asmundson, G. J., Antony, M. M., & McCabe, R. E. (2009). Pain-related anxiety and anxiety sensitivity across anxiety and depressive disorders. Journal of Anxiety Disorders, 23(6), 791–798.
Carleton, R. N., & Asmundson, G. J. (2009). The multidimensionality of fear of pain: Construct independence for the Fear of Pain Questionnaire-Short Form and the Pain Anxiety Symptoms Scale-20. The Journal of Pain, 10(1), 29–37.
Crombez, G., Eccleston, C., Baeyens, F., Van Houdenhove, B., & Van Den Broeck, A. (1999). Attention to chronic pain is dependent upon pain-related fear. Journal of Psychosomatic Research, 47(5), 403–410.
Crombez, G., Vlaeyen, J. W., Heuts, P. H., & Lysens, R. (1999). Pain-related fear is more disabling than pain itself: Evidence on the role of pain-related fear in chronic back pain disability. Pain, 80(1–2), 329–339.
Dhingra, L. K., Homel, P., Grossman, B., Chen, J., Scharaga, E., Calamita, S., et al. (2014). Ecological momentary assessment of smoking behavior in persistent pain patients. The Clinical Journal of Pain, 30(3), 205–213.
Ditre, J. W., & Brandon, T. H. (2008). Pain as a motivator of smoking: Effects of pain induction on smoking urge and behavior. Journal of Abnormal Psychology, 117(2), 467.
Ditre, J. W., Brandon, T. H., Zale, E. L., & Meagher, M. M. (2011). Pain, nicotine, and smoking: Research findings and mechanistic considerations. Psychological Bulletin, 137(6), 1065.
Ditre, J. W., Heckman, B. W., Butts, E. A., & Brandon, T. H. (2010). Effects of expectancies and coping on pain-induced motivation to smoke. Journal of Abnormal Psychology, 119(3), 524.
Ditre, J. W., Heckman, B. W., Zale, E. L., Kosiba, J. D., & Maisto, S. A. (2016). Acute analgesic effects of nicotine and tobacco in humans: A meta-analysis. Pain. https://doi.org/10.1097/j.pain.0000000000000572.
Ditre, J. W., Kosiba, J. D., Zale, E. L., Zvolensky, M. J., & Maisto, S. A. (2016). Chronic pain status, nicotine withdrawal, and expectancies for smoking cessation among lighter smokers. Annals of Behavioral Medicine, 50(3), 427–435.
Ditre, J. W., Langdon, K. J., Kosiba, J. D., Zale, E. L., & Zvolensky, M. J. (2015). Relations between pain-related anxiety, tobacco dependence, and barriers to quitting among a community-based sample of daily smokers. Addictive Behaviors, 42, 130–135. https://doi.org/10.1016/j.addbeh.2014.11.032.
Ditre, J. W., Zale, E. L., Heckman, B. W., & Hendricks, P. S. (2017). A measure of perceived pain and tobacco smoking interrelations: Pilot validation of the pain and smoking inventory. Cognitive Behaviour Therapy, 46(4), 339–351.
Ditre, J. W., Zale, E. L., Kosiba, J. D., & Zvolensky, M. J. (2013). A pilot study of pain-related anxiety and smoking-dependence motives among persons with chronic pain. Experimental and Clinical Psychopharmacology, 21(6), 443–449. https://doi.org/10.1037/a0034174.
Ditre, J. W., Zale, E. L., LaRowe, L. R., Kosiba, J. D., & De Vita, M. J. (2018). Nicotine deprivation increases pain intensity, neurogenic inflammation, and mechanical hyperalgesia among daily tobacco smokers. Journal of Abnormal Psychology. https://doi.org/10.1037/abn0000353.
Edwards, R., Augustson, E. M., & Fillingim, R. (2000). Sex-specific effects of pain-related anxiety on adjustment to chronic pain. The Clinical Journal of Pain, 16(1), 46–53.
Esteve, M. R., & Camacho, L. (2008). Anxiety sensitivity, body vigilance and fear of pain. Behaviour Research and Therapy, 46(6), 715–727.
Feldner, M. T., Zvolensky, M. J., Babson, K., Leen-Feldner, E. W., & Schmidt, N. B. (2008). An integrated approach to panic prevention targeting the empirically supported risk factors of smoking and anxiety sensitivity: Theoretical basis and evidence from a pilot project evaluating feasibility and short-term efficacy. Journal of Anxiety Disorders, 22(7), 1227–1243.
Flink, I. K., Nicholas, M. K., Boersma, K., & Linton, S. J. (2009). Reducing the threat value of chronic pain: A preliminary replicated single-case study of interoceptive exposure versus distraction in six individuals with chronic back pain. Behaviour Research and Therapy, 47(8), 721–728.
Gonzalez, A., Hogan, J., McLeish, A. C., & Zvolensky, M. J. (2010). An evaluation of pain-related anxiety among daily cigarette smokers in terms of negative and positive reinforcement smoking outcome expectancies. Addictive Behaviors, 35(6), 553–557. https://doi.org/10.1016/j.addbeh.2010.01.005.
Gonzalez, A., Zvolensky, M. J., Hogan, J., McLeish, A. C., & Weibust, K. S. (2011). Anxiety sensitivity and pain-related anxiety in the prediction of fear responding to bodily sensations: A laboratory test. Journal of Psychosomatic Research, 70(3), 258–266.
Gonzalez, A., Zvolensky, M. J., Vujanovic, A. A., Leyro, T. M., & Marshall, E. C. (2008). An evaluation of anxiety sensitivity, emotional dysregulation, and negative affectivity among daily cigarette smokers: Relation to smoking motives and barriers to quitting. Journal of Psychiatric Research, 43(2), 138–147.
Hayes, S. C., Wilson, K. G., Gifford, E. V., Follette, V. M., & Strosahl, K. (1996). Experiential avoidance and behavioral disorders: A functional dimensional approach to diagnosis and treatment. Journal of Consulting and Clinical Psychology, 64(6), 1152.
Haynes, S. N., & O’Brien, W. H. (1990). Functional analysis in behavior therapy. Clinical Psychology Review, 10(6), 649–668.
Hooten, W. M., Shi, Y., Gazelka, H. M., & Warner, D. O. (2011). The effects of depression and smoking on pain severity and opioid use in patients with chronic pain. Pain, 152(1), 223–229. https://doi.org/10.1016/j.pain.2010.10.045
Hooten, W. M., Townsend, C. O., Bruce, B. K., Schmidt, J. E., Kerkvliet, J. L., Patten, C. A., et al. (2009). Effects of smoking status on immediate treatment outcomes of multidisciplinary pain rehabilitation. Pain Medicine, 10(2), 347–355. https://doi.org/10.1111/j.1526-4637.2008.00494.x.
Hughes, J. R., & Hatsukami, D. (1986). Signs and symptoms of tobacco withdrawal. Archives of General Psychiatry, 43(3), 289–294.
IOM. (2011). Relieving pain in America: A blueprint for transforming prevention, care, education, and research. Washington, DC: The National Academies Press.
Jamal, A., King, B. A., Neff, L. J., Whitmill, J., Babb, S. D., & Graffunder, C. M. (2016). Current cigarette smoking among adults—United States, 2005–2015. MMWR Morbidity and Mortality Weekly Report, 65, 1205–1211. https://doi.org/10.15585/mmwr.mm6544a2.
Johnson, K. A., Farris, S. G., Schmidt, N. B., Smits, J. A., & Zvolensky, M. J. (2013). Panic attack history and anxiety sensitivity in relation to cognitive-based smoking processes among treatment-seeking daily smokers. Nicotine & Tobacco Research, 15(1), 1–10.
Johnson, K. A., Farris, S. G., Schmidt, N. B., & Zvolensky, M. J. (2012). Anxiety sensitivity and cognitive-based smoking processes: Testing the mediating role of emotion dysregulation among treatment-seeking daily smokers. Journal of Addictive Diseases, 31(2), 143–157.
Johnson, K. A., Zvolensky, M. J., Marshall, E. C., Gonzalez, A., Abrams, K., & Vujanovic, A. A. (2008). Linkages between cigarette smoking outcome expectancies and negative emotional vulnerability. Addictive Behaviors. 33(11), 1416–1424. https://doi.org/10.1016/j.addbeh.2008.05.001
Kassel, J. D., & Unrod, M. (2000). Smoking, anxiety, and attention: support for the role of nicotine in attentionally mediated anxiolysis. Journal of Abnormal Psychology, 109(1), 161.
Keogh, E., & Birkby, J. (1999). The effect of anxiety sensitivity and gender on the experience of pain. Cognition & Emotion, 13(6), 813–829.
Keogh, E., Book, K., Thomas, J., Giddins, G., & Eccleston, C. (2010). Predicting pain and disability in patients with hand fractures: Comparing pain anxiety, anxiety sensitivity and pain catastrophizing. European Journal of Pain, 14(4), 446–451.
Keogh, E., & Cochrane, M. (2002). Anxiety sensitivity, cognitive biases, and the experience of pain. The Journal of Pain, 3(4), 320–329.
Keogh, E., Ellery, D., Hunt, C., & Hannent, I. (2001). Selective attentional bias for pain-related stimuli amongst pain fearful individuals. Pain, 91(1–2), 91–100.
Keogh, E., Hamid, R., Hamid, S., & Ellery, D. (2004). Investigating the effect of anxiety sensitivity, gender and negative interpretative bias on the perception of chest pain. Pain, 111(1–2), 209–217.
Khantzian, E. J. (1997). The self-medication hypothesis of substance use disorders: A reconsideration and recent applications. Harvard Review of Psychiatry, 4(5), 231–244.
Klages, U., Kianifard, S., Ulusoy, Ö, & Wehrbein, H. (2006). Anxiety sensitivity as predictor of pain in patients undergoing restorative dental procedures. Community Dentistry and Oral Epidemiology, 34(2), 139–145.
Kosiba, J. D., Zale, E. L., & Ditre, J. W. (2018). Associations between pain intensity and urge to smoke: Testing the role of negative affect and pain catastrophizing. Drug & Alcohol Dependence, 187, 100–108. https://doi.org/10.1016/j.drugalcdep.2018.01.037.
Lang, A. J., Sorrell, J. T., Rodgers, C. S., & Lebeck, M. M. (2006). Anxiety sensitivity as a predictor of labor pain. European Journal of Pain, 10(3), 263–263.
Langdon, K. J., Farris, S. G., Øverup, C. S., & Zvolensky, M. J. (2015). Associations between anxiety sensitivity, negative affect, and smoking during a self-guided smoking cessation attempt. Nicotine & Tobacco Research, 18(5), 1188–1195.
LaRowe, L. R., Farris, S. G., Zvolensky, M. J., & Ditre, J. W. (in press). Associations between past-month pain and distress intolerance among daily cigarette smokers. Journal of Studies on Alcohol and Drugs.
LaRowe, L. R., Langdon, K. J., Zvolensky, M. J., Zale, E. L., & Ditre, J. W. (2017). Pain-related anxiety as a predictor of early lapse and relapse to cigarette smoking. Experimental and Clinical Psychopharmacology, 25(4), 255–264. https://doi.org/10.1037/pha0000127.
Leahy, R. L. (1996). Cognitive therapy: Basic principles and applications. Northvale, NJ: Jason Aronson Inc.
Leeuw, M., Goossens, M. E., Linton, S. J., Crombez, G., Boersma, K., & Vlaeyen, J. W. (2007). The fear-avoidance model of musculoskeletal pain: Current state of scientific evidence. Journal of Behavioral Medicine, 30(1), 77–94.
Leventhal, A. M., & Zvolensky, M. J. (2015). Anxiety, depression, and cigarette smoking: A transdiagnostic vulnerability framework to understanding emotion—Smoking comorbidity. Psychological Bulletin, 141(1), 176.
Leyro, T. M., Zvolensky, M. J., Vujanovic, A. A., & Bernstein, A. (2008). Anxiety sensitivity and smoking motives and outcome expectancies among adult daily smokers: Replication and extension. Nicotine & Tobacco Research, 10(6), 985–994.
Lumley, M. A., Cohen, J. L., Borszcz, G. S., Cano, A., Radcliffe, A. M., Porter, L. S., et al. (2011). Pain and emotion: A biopsychosocial review of recent research. Journal of Clinical Psychology, 67(9), 942–968.
McCabe, R. E., Chudzik, S. M., Antony, M. M., Young, L., Swinson, R. P., & Zolvensky, M. J. (2004). Smoking behaviors across anxiety disorders. Journal of Anxiety Disorders, 18(1), 7–18.
McCracken, L., Gross, R., & Eccleston, C. (2002). Multimethod assessment of treatment process in chronic low back pain: Comparison of reported pain-related anxiety with directly measured physical capacity. Behaviour Research and Therapy, 40(5), 585–594.
McCracken, L. M., & Dhingra, L. (2002). A short version of the Pain Anxiety Symptoms Scale (PASS-20): Preliminary development and validity. Pain Research and Management, 7(1), 45–50. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/16231066.
McCracken, L. M., Faber, S. D., & Janeck, A. S. (1998). Pain-related anxiety predicts non-specific physical complaints in persons with chronic pain. Behaviour Research and Therapy, 36(6), 621–630.
McCracken, L. M., & Gross, R. T. (1993). Does anxiety affect coping with chronic pain? Clinical Journal of Pain, 9(4), 253–259.
McCracken, L. M., & Gross, R. T. (1998). The role of pain-related anxiety reduction in the outcome of multidisciplinary treatment for chronic low back pain: Preliminary results. Journal of Occupational Rehabilitation, 8(3), 179–189.
McCracken, L. M., Gross, R. T., Aikens, J., & Carnrike, C. L. M. Jr. (1996). The assessment of anxiety and fear in persons with chronic pain: A comparison of instruments. Behaviour Research and Therapy, 34(11–12), 927–933. https://doi.org/10.1016/s0005-7967(96)00057-5.
McCracken, L. M., Gross, R. T., Sorg, P. J., & Edmands, T. A. (1993). Prediction of pain in patients with chronic low back pain: Effects of inaccurate prediction and pain-related anxiety. Behaviour Research and Therapy, 31(7), 647–652. https://doi.org/10.1016/0005-7967(93)90117-D.
McCracken, L. M., Zayfert, C., & Gross, R. T. (1992). The Pain Anxiety Symptoms Scale: Development and validation of a scale to measure fear of pain. Pain, 50(1), 67–73. https://doi.org/10.1016/0304-3959(92)90113-P.
McEvoy, P. M., Nathan, P., & Norton, P. J. (2009). Efficacy of transdiagnostic treatments: A review of published outcome studies and future research directions. Journal of Cognitive Psychotherapy, 23(1), 20.
McLeish, A. C., Zvolensky, M. J., Bonn-Miller, M. O., & Bernstein, A. (2006). Perceived health moderates the association between smoking rate and panic vulnerability variables among daily smokers. Depression and Anxiety, 23(5), 257–265.
Michna, E., Ross, E. L., Hynes, W. L., Nedeljkovic, S. S., Soumekh, S., Janfaza, D., et al. (2004). Predicting aberrant drug behavior in patients treated for chronic pain: Importance of abuse history. Journal of Pain and Symptom Management, 28(3), 250–258. https://doi.org/10.1016/j.jpainsymman.2004.04.007.
Morissette, S. B., Brown, T. A., Kamholz, B. W., & Gulliver, S. B. (2006). Differences between smokers and nonsmokers with anxiety disorders. Journal of Anxiety Disorders, 20(5), 597–613.
Mullane, J. C., Stewart, S. H., Rhyno, E., Steeves, D., Watt, M., & Eisner, A. (2008). Anxiety, sensitivity and difficulties with smoking cessation. In A. M. Columbus (Ed.), Advances in psychology research (Vol. 54, pp. 141–155). Hauppauge, NY: Nova Science Publishers.
Nolen-Hoeksema, S., & Watkins, E. R. (2011). A heuristic for developing transdiagnostic models of psychopathology: Explaining multifinality and divergent trajectories. Perspectives on Psychological Science, 6(6), 589–609.
Norton, P. J., & Asmundson, G. J. (2004). Anxiety sensitivity, fear, and avoidance behavior in headache pain. Pain, 111(1–2), 218–223.
O’connor, R. M., Farrow, S., & Colder, C. R. (2008). Clarifying the anxiety sensitivity and alcohol use relation: Considering alcohol expectancies as moderators. Journal of Studies on Alcohol and Drugs, 69(5), 765–772.
Ocañez, K. L., Kathryn McHugh, R., & Otto, M. W. (2010). A meta-analytic review of the association between anxiety sensitivity and pain. Depression and Anxiety, 27(8), 760–767.
Ochsner, K. N., Ludlow, D. H., Knierim, K., Hanelin, J., Ramachandran, T., Glover, G. C., & Mackey, S. C. (2006). Neural correlates of individual differences in pain-related fear and anxiety. Pain, 120(1–2), 69–77.
Orhurhu, V. J., Pittelkow, T. P., & Hooten, W. M. (2015). Prevalence of smoking in adults with chronic pain. Tobacco Induced Diseases, 13(1), 17. https://doi.org/10.1186/s12971-015-0042-y.
Parkerson, H. A., & Asmundson, G. J. (2016). The role of pain intensity and smoking expectancies on smoking urge and behavior following experimental pain induction. Drug & Alcohol Dependence, 164, 166–171.
Patterson, A. L., Gritzner, S., Resnick, M. P., Dobscha, S. K., Turk, D. C., & Morasco, B. J. (2012). Smoking cigarettes as a coping strategy for chronic pain is associated with greater pain intensity and poorer pain-related function. Journal of Pain, 13(3), 285–292. https://doi.org/10.1016/j.jpain.2011.11.008.
Peters, M. L., Vlaeyen, J. W., & Weber, W. E. (2005). The joint contribution of physical pathology, pain-related fear and catastrophizing to chronic back pain disability. Pain, 113(1–2), 45–50.
Reiss, S. (1985). Theoretical issues in behavior therapy. New York, NY: Academic Press.
Reiss, S. (1991). Expectancy model of fear, anxiety, and panic. Clinical Psychology Review, 11(2), 141–153.
Reiss, S., Peterson, R. A., Gursky, D. M., & McNally, R. J. (1986). Anxiety sensitivity, anxiety frequency and the prediction of fearfulness. Behaviour Research and Therapy, 24(1), 1–8.
Shiri, R., Karppinen, J., Leino-Arjas, P., Solovieva, S., & Viikari-Juntura, E. (2010). The association between smoking and low back pain: A meta-analysis. The American Journal of Medicine. 123(1), 87.e7–87.e35.
Simons, L. E., Elman, I., & Borsook, D. (2014). Psychological processing in chronic pain: A neural systems approach. Neuroscience & Biobehavioral Reviews, 39, 61–78.
Smits, J. A., Zvolensky, M. J., Davis, M. L., Rosenfield, D., Marcus, B. H., Church, T. S., et al. (2016). The efficacy of vigorous-intensity exercise as an aid to smoking cessation in adults with high anxiety sensitivity: A randomized controlled trial. Psychosomatic Medicine, 78(3), 354.
Stewart, S. H., & Asmundson, G. J. (2006). Anxiety sensitivity and its impact on pain experiences and conditions: A state of the art. Cognitive Behaviour Therapy, 35(4), 185–188.
Sugiyama, D., Nishimura, K., Tamaki, K., Tsuji, G., Nakazawa, T., Morinobu, A., et al. (2010). Impact of smoking as a risk factor for developing rheumatoid arthritis: A meta-analysis of observational studies. Annals of the Rheumatic Diseases, 69(01), 70–81.
Sullivan, M. J., Bishop, S. R., & Pivik, J. (1995). The pain catastrophizing scale: Development and validation. Psychological Assessment, 7(4), 524.
Taylor, S., & Cox, B. J. (1998). An expanded anxiety sensitivity index: Evidence for a hierarchic structure in a clinical sample. Journal of Anxiety Disorders, 12(5), 463–483.
Taylor, S., Zvolensky, M. J., Cox, B. J., Deacon, B., Heimberg, R. G., Ledley, D. R., et al. (2007). Robust dimensions of anxiety sensitivity: Development and initial validation of the Anxiety Sensitivity Index-3. Psychological Assessment, 19(2), 176–188. https://doi.org/10.1037/1040-3590.19.2.176.
Tiffany, S. T., & Carter, B. L. (1998). Is craving the source of compulsive drug use? Journal of Psychopharmacology, 12(1), 23–30.
Turk, D. C., & Okifuji, A. (2001). Pain terms and taxonomies of pain. In J. D. Loeser, C. R. Chapman, D. C. Turk & S. H. Butler (Eds.), Bonica’s management of pain (3 edn.). Hagerstown: Lippincott Williams & Wilkins.
Turk, D. C., & Wilson, H. D. (2010). Fear of pain as a prognostic factor in chronic pain: Conceptual models, assessment, and treatment implications. Current Pain and Headache Reports, 14(2), 88–95.
US Department of Health and Human Services. (2014). The health consequences of smoking—50 years of progress: A report of the Surgeon General (p. 17). Atlanta, GA: US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health.
Vlaeyen, J. W., Kole-Snijders, A. M., Rotteveel, A. M., Ruesink, R., & Heuts, P. H. (1995). The role of fear of movement/(re) injury in pain disability. Journal of Occupational Rehabilitation, 5(4), 235–252.
Vlaeyen, J. W., & Linton, S. J. (2000). Fear-avoidance and its consequences in chronic musculoskeletal pain: A state of the art. Pain, 85(3), 317–332. https://doi.org/10.1016/S0304-3959(99)00242-0.
Vowles, K. E., Zvolensky, M. J., Gross, R. T., & Sperry, J. A. (2004). Pain-related anxiety in the prediction of chronic low-back pain distress. Journal of Behavioral Medicine, 27(1), 77–89.
Waddell, G., Newton, M., Henderson, I., Somerville, D., & Main, C. J. (1993). A Fear-Avoidance Beliefs Questionnaire (FABQ) and the role of fear-avoidance beliefs in chronic low back pain and disability. Pain, 52(2), 157–168.
Watt, M. C., Stewart, S. H., Lefaivre, M. J., & Uman, L. S. (2006). A brief cognitive-behavioral approach to reducing anxiety sensitivity decreases pain-related anxiety. Cognitive Behaviour Therapy, 35(4), 248–256.
Zale, E. L., & Ditre, J. W. (2015). Pain-related fear, disability, and the fear-avoidance model of chronic pain. Current Opinion in Psychology, 5, 24–30.
Zale, E. L., Ditre, J. W., Dorfman, M. L., Heckman, B. W., & Brandon, T. H. (2014). Smokers in pain report lower confidence and greater difficulty quitting. Nicotine & Tobacco Research. https://doi.org/10.1093/ntr/ntu077.
Zale, E. L., Maisto, S. A., & Ditre, J. W. (2016). Anxiety and depression in bidirectional relations between pain and smoking: Implications for smoking cessation. Behavior Modification, 40(1–2), 7–28.
Zinbarg, R. E., Barlow, D. H., & Brown, T. A. (1997). Hierarchical structure and general factor saturation of the Anxiety Sensitivity Index: Evidence and implications. Psychological Assessment, 9(3), 277.
Zvolensky, M., Bonn-Miller, M., Bernstein, A., & Marshall, E. (2006). Anxiety sensitivity and abstinence duration to smoking. Journal of Mental Health, 15(6), 659–670.
Zvolensky, M., Rosenfield, D., Garey, L., Kauffman, B., Langdon, K., Powers, M. et al. (2018). Does exercise aid smoking cessation through reductions in anxiety sensitivity and dysphoria? Health Psychology. https://doi.org/10.1037/hea0000588.
Zvolensky, M. J., Bogiaizian, D., Salazar, P. L., Farris, S. G., & Bakhshaie, J. (2014). An anxiety sensitivity reduction smoking-cessation program for Spanish-speaking smokers (Argentina). Cognitive and Behavioral Practice, 21(3), 350–363.
Zvolensky, M. J., Farris, S. G., Leventhal, A. M., & Schmidt, N. B. (2014). Anxiety sensitivity mediates relations between emotional disorders and smoking. Psychology of Addictive Behaviors, 28(3), 912.
Zvolensky, M. J., Feldner, M. T., Leen-Feldner, E., Bonn-Miller, M. O., McLeish, A. C., & Gregor, K. (2004). Evaluating the role of anxiety sensitivity in smoking outcome expectancies among regular smokers. Cognitive Therapy and Research, 28(4), 473–486.
Zvolensky, M. J., Garey, L., Allan, N. P., Farris, S. G., Raines, A. M., Smits, J. A., et al. (2018). Effects of anxiety sensitivity reduction on smoking abstinence: An analysis from a panic prevention program. Journal of Consulting and Clinical Psychology, 86(5), 474.
Zvolensky, M. J., Goodie, J. L., McNeil, D. W., Sperry, J. A., & Sorrell, J. T. (2001). Anxiety sensitivity in the prediction of pain-related fear and anxiety in a heterogeneous chronic pain population. Behaviour Research and Therapy, 39(6), 683–696.
Zvolensky, M. J., Lejuez, C., Kahler, C. W., & Brown, R. A. (2003). Integrating an interoceptive exposure-based smoking cessation program into the cognitive-behavioral treatment of panic disorder: Theoretical relevance and case demonstration. Cognitive and Behavioral Practice, 10(4), 347–357.
Zvolensky, M. J., McMillan, K., Gonzalez, A., & Asmundson, G. J. (2009). Chronic pain and cigarette smoking and nicotine dependence among a representative sample of adults. Nicotine & Tobacco Research, 11(12), 1407–1414. https://doi.org/10.1093/ntr/ntp153.
Zvolensky, M. J., Stewart, S. H., Vujanovic, A. A., Gavric, D., & Steeves, D. (2009). Anxiety sensitivity and anxiety and depressive symptoms in the prediction of early smoking lapse and relapse during smoking cessation treatment. Nicotine & Tobacco Research, 11(3), 323–331.
Zvolensky, M. J., Yartz, A. R., Gregor, K., Gonzalez, A., & Bernstein, A. (2008). Interoceptive exposure-based cessation intervention for smokers high in anxiety sensitivity: A case series. Journal of Cognitive Psychotherapy, 22(4), 346–365. https://doi.org/10.1891/0889-8391.22.4.346.
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Lisa R. LaRowe, Michael J. Zvolensky, & Joseph W. Ditre declare that they have no conflict of interest.
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LaRowe, L.R., Zvolensky, M.J. & Ditre, J.W. The Role of Anxiety-Relevant Transdiagnostic Factors in Comorbid Chronic Pain and Tobacco Cigarette Smoking. Cogn Ther Res 43, 102–113 (2019). https://doi.org/10.1007/s10608-018-9957-y
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DOI: https://doi.org/10.1007/s10608-018-9957-y