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State-of-the-art approach for bone sarcomas

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Abstract

Bone sarcomas are a variety of non-epithelial, malignant neoplasms of bone. The most common bone sarcomas are osteosarcoma, Ewing’s sarcoma, and chondrosarcoma. The approach to a patient with a suspected bone sarcoma from initial examination to the histological diagnosis and classification is staging. Staging is of critical importance, in order to classify different treatment options and point out which combination of them is more suitable depending on the severity of the tumor in every individual patient. Staging should include medical history, physical and imaging examination, and biopsy. This article presents the current approach for staging, principles of biopsy, tumor classification, treatment, and follow-up of patients with bone sarcomas.

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None of the authors have any financial and personal relationships with other people or organizations that could inappropriately influence (bias) their work.

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Authors and Affiliations

  1. First Department of Orthopaedics, ATTIKON University Hospital, Athens University Medical School, 41 Ventouri Street, Holargos, 15562, Athens, Greece

    Andreas F. Mavrogenis, Christos Vottis & Panayiotis J. Papagelopoulos

  2. Department of Orthopaedics, Istituto Ortopedico Rizzoli, Bologna, Italy

    Andrea Angelini & Pietro Ruggieri

  3. Department of Radiology and Interventional Radiology, Istituto Ortopedico Rizzoli, Bologna, Italy

    Eugenio Rimondi & Giuseppe Rossi

  4. Department of Medical Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy

    Emanuela Palmerini

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  1. Andreas F. Mavrogenis
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  2. Andrea Angelini
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Correspondence to Andreas F. Mavrogenis.

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Mavrogenis, A.F., Angelini, A., Vottis, C. et al. State-of-the-art approach for bone sarcomas. Eur J Orthop Surg Traumatol 25, 5–15 (2015). https://doi.org/10.1007/s00590-014-1468-2

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