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National outcomes and uptake of laparoscopic gastrectomy for cancer in England

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Abstract

Background

Gastrectomy remains the mainstay of curative treatment for gastric cancer, yet it is associated with significant postoperative mortality. The laparoscopic approach has been introduced in an attempt to improve surgical outcomes. This study examines the uptake of laparoscopic gastrectomy in England and quantifies postoperative mortality and morbidity following gastrectomy for cancer.

Methods

A population-based study of a national administrative database was undertaken. Patients undergoing gastrectomy for cancer in any National Health Services hospital in England between April 2000 and March 2010 were included. The main outcome measures were mortality, morbidity and length of stay.

Results

A total of 10,713 patients underwent gastrectomy, of which 10,233 (95.5 %) underwent open gastrectomy (OG), and 480 (4.5 %) underwent laparoscopic gastrectomy (LG). There was no significant difference in 30-day in-hospital mortality between OG and LG (5.6 % vs. 4.8 %; p = 0.461). Medical complications occurred in 2,311 (22.6 %) and 120 (25 %) patients from OG and LG groups respectively (p = 0.217). Patients in the LG groups had a shorter hospital stay than OG with median (interquartile range) of 11 (8–17) versus 14 (11–19) days respectively (p < 0.001). Readmission and reoperation rates were 10.2 versus 12.1 % (p = 0.175) and 4 versus 4.6 % (p = 0.523) for OG and LG respectively.

Conclusions

LG is increasingly being performed in England. Postoperative morbidity and mortality of LG is similar to that of OG, but it is associated with a shorter hospital stay. Data from randomised controlled trials evaluating long term survival and patients’ reported outcomes are essential before the final judgement on the value of LG in the management of gastric cancer.

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Disclosures

  Ravikrishna Mamidanna, Alex M, Almoudaris, Omar Faiz, and George Hanna have no conflict of interest or financial ties to report. Paul Aylin and Alex Bottle are part of the Dr. Foster Unit at Imperial College, which is affiliated with the Centre for Patient Safety and Service Quality at Imperial College Healthcare NHS Trust funded by the National Institute of Health Research. The Unit is largely funded by a research grant from Dr. Foster Intelligence (an independent health service research organisation).

Ethics approval

  We have approval under Section 251 (formerly Section 60) granted by the National Information Governance Board for Health and Social Care (formerly the Patient Information Advisory Group). We have had approval for using these data for research from the South East Research Ethics Committee.

Author information

Authors and Affiliations

  1. Department of Surgery and Cancer, Imperial College, St Mary’s Hospital, South Wharf Road, London, W21NY, UK

    Ravikrishna Mamidanna, Alex M. Almoudaris & Omar Faiz

  2. Dr. Foster Unit, Department of Primary Care and Social Medicine, Imperial College, 1st Floor Jarvis House, 12 Smithfield Street, London, EC1A 9LA, UK

    Alex Bottle & Paul Aylin

  3. Division of Surgery, Imperial College London, 10th Floor, QEQM Building, St Mary’s Hospital, South Wharf Road, London, W21NY, UK

    George B. Hanna

Authors
  1. Ravikrishna Mamidanna
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  4. Paul Aylin
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  5. Omar Faiz
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  6. George B. Hanna
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Corresponding author

Correspondence to George B. Hanna.

Appendix

Appendix

See Tables 6 and 7.

Table 6 Medical comorbidities and complications with ICD-10 diagnosis codes
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Table 7 Subgroup analyses: unadjusted short term outcomes following elective partial and total gastrectomy for cancer
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Mamidanna, R., Almoudaris, A.M., Bottle, A. et al. National outcomes and uptake of laparoscopic gastrectomy for cancer in England. Surg Endosc 27, 3348–3358 (2013). https://doi.org/10.1007/s00464-013-2916-5

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  • DOI: https://doi.org/10.1007/s00464-013-2916-5

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