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Efficacy of laparoscopy-assisted distal gastrectomy for gastric cancer in the elderly

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Abstract

Background

To date, it has been unclear whether laparoscopy-assisted distal gastrectomy (LADG) is a suitable treatment for elderly patients with early gastric cancer. This study retrospectively compared surgical outcomes between elderly and nonelderly patients with gastric cancer.

Methods

The study group was comprised of 211 patients who underwent distal gastrectomy between April 2000 and March 2007. Of these, 130 patients (26 aged ≥75 years and 104 aged <75 years) underwent LADG, and the remaining 81 patients underwent conventional open distal gastrectomy (ODG). Short- and long-term patient outcomes were evaluated.

Results

The operation time was significantly longer in the LADG group than in the ODG group (262.6 versus 234.3 min, p = 0.005), but the other short-term outcomes did not differ between the two groups. When performed by an experienced surgeon, blood loss was significantly reduced, while operation time for LADG was similar to that for ODG. Within the LADG group, incidences of comorbid disease and lymph-node metastasis were significantly greater, the histological tumor type was significantly more differentiated, and the macroscopically depressed tumor type was less common in elderly patients. However, the incidence of postoperative morbidity did not differ between the elderly and nonelderly groups (11.5% versus 3.8%, p = 0.1201), and there was no significant difference in postoperative course. Logistic regression analysis showed that body mass index, but not chronological age, was an independent predictive factor of postoperative morbidity (odds ratio = 3.674, p = 0.045). There were no significant differences in overall or disease-specific survival between elderly and nonelderly patients.

Conclusion

LADG is an effective treatment for elderly patients with early gastric cancer if it is performed by an experienced surgeon. A high-volume study is needed to confirm this rationale.

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Authors and Affiliations

  1. Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57 Urafune-cho, Minami-ku, Yokohama, 232-0024, Japan

    Chikara Kunisaki, Hirochika Makino, Ryo Takagawa, Takashi Oshima & Yasuhiko Nagano

  2. Department of Gastroenterological Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan

    Hidetaka A. Ono, Hirotoshi Akiyama & Hiroshi Shimada

Authors
  1. Chikara Kunisaki
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  2. Hirochika Makino
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  3. Ryo Takagawa
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  4. Takashi Oshima
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  5. Yasuhiko Nagano
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  6. Hidetaka A. Ono
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  7. Hirotoshi Akiyama
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  8. Hiroshi Shimada
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Correspondence to Chikara Kunisaki.

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Kunisaki, C., Makino, H., Takagawa, R. et al. Efficacy of laparoscopy-assisted distal gastrectomy for gastric cancer in the elderly. Surg Endosc 23, 377–383 (2009). https://doi.org/10.1007/s00464-008-9949-1

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  • DOI: https://doi.org/10.1007/s00464-008-9949-1

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