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Therapie der Osteoporose beim geriatrischen Patienten

Osteoporotic treatment options in geriatric patients

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Zusammenfassung

Aufgrund des demographischen Wandels ist es zu einer deutlichen Zunahme der osteoporotischen Frakturen gekommen. Gerade den geriatrischen Patienten drohen nach einer Fraktur Funktionseinschränkungen sowie Verlust der Selbstständigkeit und Lebensqualität. Trotz der schwerwiegenden medizinischen und sozioökonomischen Folgen der Osteoporose gibt es in der Versorgung und Prävention noch gravierende Mängel. Im vorliegenden Review werden die aktuellen Möglichkeiten der medikamentösen, nichtmedikamentösen und operativen Therapie bei geriatrischen Patienten aufgezeigt und anhand der Datenlage diskutiert.

Abstract

Due to the demographic changes of the last few decades, there has been a significant increase in the number of osteoporotic fractures. After a fracture, geriatric patients are at particularly high risk for an increase of their functional impairments as well as a loss of independence and quality of life. In spite of the severe medical and socioeconomic consequences of fragility fractures, osteoporotic treatment and prevention are still insufficient. Based on the current literature, the pharmacological and nonpharmacological treatment options as well as new surgical techniques for geriatric patients are reviewed.

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Interessenkonflikt

Der korrespondierende Autor gibt für sich und seine Koautoren folgende Beziehungen an: M. Gosch erhält Vortraghonorare von den Firmen Amgen GmbH, Eli Lilly GmbH, Servier Asustria, Roche Austria; P. Pietschmann erhält Forschungsunterstützungen und/oder Honorare von den Firmen Amgen GmbH, Eli Lilly GmbH, Leo Pharma, Merck, Sharp Dohme GmbH, Nycomed Pharma, Novartis Pharma, Roche Austria, Servier Austria, Institute des Recherches Internationales Servier, Shire, Sanofi Aventis; bei den anderen Koautoren besteht kein Interessenkonflikt.

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Authors and Affiliations

  1. Abteilung für Innere Medizin und Akutgeriatrie, Landeskrankenhaus Hochzirl, Hochzirl 1, 6170, Zirl, Österreich

    M. Gosch MAS, M. Lechleitner, U. Benvenuti-Falger & B. Joosten-Gstrein

  2. Universitätsklinik für Unfallchirurgie, Innsbruck, Österreich

    C. Kammerlander & T. Roth

  3. Institut für Physikalische Medizin und Rehabilitation, SMZ Sophienspital, Wien, Österreich

    K. Pils

  4. Institut für Pathophysiologie und Allergieforschung, Zentrum für Pathophysiologie, Infektiologie und Immunologie, Universität Wien, Wien, Österreich

    P. Pietschmann

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  1. M. Gosch MAS
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  2. C. Kammerlander
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  3. K. Pils
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  4. M. Lechleitner
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  5. U. Benvenuti-Falger
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  6. T. Roth
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  7. B. Joosten-Gstrein
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  8. P. Pietschmann
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Correspondence to M. Gosch MAS.

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Gosch, M., Kammerlander, C., Pils, K. et al. Therapie der Osteoporose beim geriatrischen Patienten. Z Gerontol Geriat 45, 417–429 (2012). https://doi.org/10.1007/s00391-012-0336-0

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