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Neonatal gastrointestinal perforation in Japan: a nationwide survey

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Abstract

Purpose

The purpose of this study is to identify the current clinical features of neonatal gastrointestinal perforation in Japan.

Methods

A questionnaire about cases of neonatal gastrointestinal perforation treated in recent 5 years was sent to participating institutions of the Japanese Society of Pediatric Surgeons (JSPS).

Results

Five hundred and thirty-six neonates with gastrointestinal perforation were treated. They consisted of 42 patients with gastric rupture/perforation (GR), 33 patients with intestinal atresia/stenosis (IA), 3 patients with malrotation (ML), 118 patients with necrotizing enterocolitis (NEC), 160 patients with focal intestinal perforation (FIP), 46 patients with meconium-related ileus (MRI), 77 patients with meconium peritonitis (MP), and 57 patients with other conditions. The total mortality rate was 20.5 %. The mortality rates of the patients with GR, IA, ML, NEC, FIP, MRI, and MP were 9.5, 9.1, 0, 33.1, 20.6, 28.2, and 9.1 %, respectively. In 263 cases involving extremely low-birth-weight neonates (ELBW), 108 died (mortality rate 41.1 %). The mortality rates for ELBW with GR, NEC, FIP, MRI, MP, and other conditions were 27.3 % (3/11), 58.5 % (48/82), 21.6 % (24/111), 70.6 % (24/34), 57.1 % (4/7), and 27.8 % (5/18), respectively.

Conclusions

The mortality rates for ELBW decreased from 62.8 % in the previous survey to 41.1 % by the time of this survey.

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Acknowledgments

We thank the staff of the accredited and affiliated pediatric surgery institutions for their cooperation.

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Authors and Affiliations

  1. Committee of Academic Surveys and Advanced Medical Science, Japanese Society of Pediatric Surgeons, Tokyo, Japan

    Masahito Sato, Yoshinori Hamada, Miyuki Kohno, Kazuya Ise, Keiichi Uchida, Hiromi Ogata, Hiroaki Masuyama, Yoshiki Morotomi, Masao Yasufuku & Motoshi Wada

  2. Department of Pediatric Surgery, Kitano Hospital, The Tazuke Kofukai Medical Research Institute, 2-4-20, Ohgimachi, Kita-ku, Osaka, 530-8480, Japan

    Masahito Sato

Authors
  1. Masahito Sato
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  2. Yoshinori Hamada
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  3. Miyuki Kohno
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  4. Kazuya Ise
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  5. Keiichi Uchida
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  6. Hiromi Ogata
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  7. Hiroaki Masuyama
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  8. Yoshiki Morotomi
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  9. Masao Yasufuku
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  10. Motoshi Wada
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Corresponding author

Correspondence to Masahito Sato.

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The authors declare that they have no conflicts of interest.

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Cite this article

Sato, M., Hamada, Y., Kohno, M. et al. Neonatal gastrointestinal perforation in Japan: a nationwide survey. Pediatr Surg Int 33, 33–41 (2017). https://doi.org/10.1007/s00383-016-3985-z

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  • DOI: https://doi.org/10.1007/s00383-016-3985-z

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