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Diffusion-weighted imaging in pediatric body magnetic resonance imaging

  • Pediatric Body MRI
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Abstract

Diffusion-weighted MRI is being increasingly used in pediatric body imaging. Its role is still emerging. It is used for detection of tumors and abscesses, differentiation of benign and malignant tumors, and detection of inflamed bowel segments in inflammatory bowel disease in children. It holds great promise in the assessment of therapy response in body tumors, with apparent diffusion coefficient (ADC) value as a potential biomarker. Significant overlap of ADC values of benign and malignant processes and less reproducibility of ADC measurements are hampering its widespread use in clinical practice. With standardization of the technique, diffusion-weighted imaging (DWI) is likely to be used more frequently in clinical practice. We discuss the principles and technique of DWI, selection of b value, qualitative and quantitative assessment, and current status of DWI in evaluation of disease processes in the pediatric body.

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Authors and Affiliations

  1. Department of Diagnostic Imaging, The Hospital for Sick Children, Department of Medical Imaging, University of Toronto, 555 University Ave., Toronto, ON, M5G 1X8, Canada

    Govind B. Chavhan & Pablo Caro-Dominguez

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  1. Govind B. Chavhan
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  2. Pablo Caro-Dominguez
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Correspondence to Govind B. Chavhan.

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Chavhan, G.B., Caro-Dominguez, P. Diffusion-weighted imaging in pediatric body magnetic resonance imaging. Pediatr Radiol 46, 847–857 (2016). https://doi.org/10.1007/s00247-016-3573-3

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  • DOI: https://doi.org/10.1007/s00247-016-3573-3

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