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COPI-mediated Transport

  • Topical Review
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Abstract

COPI-coated vesicles are protein and liquid carriers that mediate transport within the early secretory pathway. In this Topical Review, we present their main protein components and discuss current models for cargo sorting. Finally, we describe the striking similarities that exist between the COPI system and the two other characterized types of vesicular carriers: COPII- and clathrin-coated vesicles.

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Acknowledgments

The authors acknowledge Patricia McCabe for carefully proofreading the manuscript. We apologize to those authors who have publications relevant to the COPI-dependent transport that were not cited in this review due to space limitations. Moreover, in many cases, review articles were cited instead of the original literature, owing to space limitations.

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  1. Biochemie Zentrum, University of Heidelberg, Im Neuenheimer Feld 328, D-69120, Heidelberg, Germany

    J. Béthune, F. Wieland & J. Moelleken

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  1. J. Béthune
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Correspondence to J. Béthune.

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Béthune, J., Wieland, F. & Moelleken, J. COPI-mediated Transport. J Membrane Biol 211, 65–79 (2006). https://doi.org/10.1007/s00232-006-0859-7

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