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Acute renal failure is not a “cute” renal failure!

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References

  1. Levy EM, Viscoli CM, Horwitz RI (1996) The effect of acute renal failure on mortality. A cohort analysis. JAMA 275:1489–1494

    CAS  PubMed  Google Scholar 

  2. Chertow GM, Levy EM, Hammermeister KE, Grover F, Daley J (1998) Independent association between acute renal failure and mortality following cardiac surgery. Am J Med 104:343–348

    CAS  PubMed  Google Scholar 

  3. Metnitz PG, Krenn CG, Steltzer H, Lang T, Ploder J, Lenz K, Le Gall JR, Druml W (2002) Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients. Crit Care Med 30:2051–2058

    Google Scholar 

  4. Kellum JA, Angus DC (2002) Patients are dying of acute renal failure. Crit Care Med 30:2156–2157

    Article  PubMed  Google Scholar 

  5. Rabb H, Daniels F, O’Donnell M, Haq M, Saba SR, Keane W, Tang WW (2000) Pathophysiological role of T lymphocytes in renal ischemia-reperfusion injury in mice. Am J Physiol Renal Physiol 279:F525–531

    CAS  PubMed  Google Scholar 

  6. Kramer AA, Postler G, Salhab KF, Mendez C, Carey LC, Rabb H (1999) Renal ischemia/reperfusion leads to macrophage-mediated increase in pulmonary vascular permeability. Kidney Int 55:2362–2367

    Article  CAS  PubMed  Google Scholar 

  7. Yokota N, Daniels F, Crosson J, Rabb H (2002) Protective effect of T cell depletion in murine renal ischemia-reperfusion injury. Transplantation 74:759–763

    Article  CAS  PubMed  Google Scholar 

  8. Harper SJ, Tomson CR, Bates DO (2002) Human uremic plasma increases microvascular permeability to water and proteins in vivo. Kidney Int 61:1416–1422

    Article  CAS  PubMed  Google Scholar 

  9. Kelly KJ (2003) Distant effects of experimental renal ischemia/reperfusion injury. J Am Soc Nephrol 14:1549–1558

    CAS  PubMed  Google Scholar 

  10. Meldrum KK, Meldrum DR, Meng X, Ao L, Harken AH (2002) TNF-alpha-dependent bilateral renal injury is induced by unilateral renal ischemia-reperfusion. Am J Physiol Heart Circ Physiol 282:H540–546

    CAS  PubMed  Google Scholar 

  11. Imai Y, Parodo J, Kajikawa O, de Perrot M, Fischer S, Edwards V, Cutz E, Liu M, Keshavjee S, Martin TR, Marshall JC, Ranieri VM, Slutsky AS (2003) Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome. JAMA 289:2104–2112

    Article  PubMed  Google Scholar 

  12. Suter PM (2002) MV causes lung inflammation and systemic immune depression. A balance of fire and ice. Intensive Care Med 28:383–385

    CAS  PubMed  Google Scholar 

  13. Gormley SM, McBride WT, Armstrong MA, McClean E, MacGowan SW, Campalani G, McMurray TJ (2002) Plasma and urinary cytokine homeostasis and renal function during cardiac surgery without cardiopulmonary bypass. Cytokine 17:61–65

    Article  CAS  PubMed  Google Scholar 

  14. Haag-Weber M, Horl WH (1996) Dysfunction of polymorphonuclear leukocytes in uremia. Semin Nephrol 16:192–201

    CAS  PubMed  Google Scholar 

  15. Cohen G, Haag-Weber M, Horl WH (1997) Immune dysfunction in uremia. Kidney Int Suppl 62:S79–82

    CAS  PubMed  Google Scholar 

  16. Druml W (2001) Nutritional management of acute renal failure. Am J Kidney Dis 37:S89–94

    CAS  PubMed  Google Scholar 

  17. Van den Berghe G, Wouters PJ, Bouillon R, Weekers F, Verwaest C, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P (2003) Outcome benefit of intensive insulin therapy in the critically ill: insulin dose versus glycemic control. Crit Care Med 31:359–366

    PubMed  Google Scholar 

  18. Woodrow G, Turney JH (1992) Cause of death in acute renal failure. Nephrol Dial Transplant 7:230–234

    CAS  PubMed  Google Scholar 

  19. Cook D, Heyland D, Griffith L, Cook R, Marshall J, Pagliarello J (1999) Risk factors for clinically important upper gastrointestinal bleeding in patients requiring mechanical ventilation. Canadian Critical Care Trials Group. Crit Care Med 27:2812–2817

    Google Scholar 

  20. Fiaccadori E, Maggiore U, Clima B, Melfa L, Rotelli C, Borghetti A (2001) Incidence, risk factors and prognosis of gastrointestinal hemorrhage complicating acute renal failure. Kidney Int 59:1510–1519

    Article  CAS  PubMed  Google Scholar 

  21. Druml W (1999) Metabolic aspects of continuous renal replacement therapies. Kidney Int Suppl 72:S56–61

    CAS  PubMed  Google Scholar 

  22. Metnitz GH, Fischer M, Bartens C, Steltzer H, Lang T, Druml W (2000) Impact of acute renal failure on antioxidant status in multiple organ failure. Acta Anaesthesiol Scand 44:236–240

    Article  CAS  PubMed  Google Scholar 

  23. Vogt B, Ferrari P, Schonholzer C, Marti HP, Mohaupt M, Wiederkehr M, Cereghetti C, Serra A, Huynh-Do U, Uehlinger D, Frey FJ (2001) Prophylactic hemodialysis after radiocontrast media in patients with renal insufficiency is potentially harmful. Am J Med 111:692–698

    CAS  PubMed  Google Scholar 

  24. Fissell WH, Lou L, Abrishami S, Buffington DA, Humes HD (2003) Bioartificial kidney ameliorates gram-negative bacteria-induced septic shock in uremic animals. J Am Soc Nephrol 14:454–461

    PubMed  Google Scholar 

  25. Gettings LG, Reynolds HN, Scalea T (1999) Outcome in post-traumatic acute renal failure when continuous renal replacement therapy is applied early vs. late. Intensive Care Med 25:805–813

    CAS  PubMed  Google Scholar 

  26. Ronco C, Bellomo R, Homel P, Brendolan A, Dan M, Piccinni P, La Greca G (2000) Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomised trial. Lancet 356:26–30

    CAS  PubMed  Google Scholar 

  27. Bouman CS, Oudemans-Van Straaten HM, Tijssen JG, Zandstra DF, Kesecioglu J (2002) Effects of early high-volume continuous venovenous hemofiltration on survival and recovery of renal function in intensive care patients with acute renal failure: a prospective, randomized trial. Crit Care Med 30:2205–2211

    Article  PubMed  Google Scholar 

  28. Evanson JA, Ikizler TA, Wingard R, Knights S, Shyr Y, Schulman G, Himmelfarb J, Hakim RM (1999) Measurement of the delivery of dialysis in acute renal failure. Kidney Int 55:1501–1508

    Article  CAS  PubMed  Google Scholar 

  29. Schiffl H, Lang SM, Fischer R (2002) Daily hemodialysis and the outcome of acute renal failure. N Engl J Med 346:305–310

    Google Scholar 

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  1. Department of Medicine III, Division of Nephrology, Vienna General Hospital, Währinger Gürtel 18–20, 1090, Vienna, Austria

    Wilfred Druml

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  1. Wilfred Druml
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Correspondence to Wilfred Druml.

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Druml, W. Acute renal failure is not a “cute” renal failure!. Intensive Care Med 30, 1886–1890 (2004). https://doi.org/10.1007/s00134-004-2344-z

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  • DOI: https://doi.org/10.1007/s00134-004-2344-z

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